4-Chloro-2-methylphenylboronic acid
- CAS No.
- 209919-30-2
- Chemical Name:
- 4-Chloro-2-methylphenylboronic acid
- Synonyms
- AKOS BRN-0229;4-CHLORO-2-METHYLPHENYL;2-Borono-5-chlorotoluene;4-chloro-o-tolylboronic acid;4-CHLORO-O-TOLUENEBORONIC ACID;4-Chloro-2-Methylphenylboronic;(4-chloro-2-methylphenyl)boronicaci;4-Chloro-2-methylphenylboronic acid;4-CHLORO-2-METHYLBENZENEBORONIC ACID;(2-Methyl-4-chlorophenyl)boronic acid
- CBNumber:
- CB0146513
- Molecular Formula:
- C7H8BClO2
- Molecular Weight:
- 170.4
- MDL Number:
- MFCD02683107
- MOL File:
- 209919-30-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 193-195°C |
|---|---|
| Boiling point | 314.9±52.0 °C(Predicted) |
| Density | 1.26±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 8.47±0.58(Predicted) |
| color | White to Almost white |
| InChIKey | SRXXSLUUAWHGBZ-UHFFFAOYSA-N |
| CAS DataBase Reference | 209919-30-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
4-Chloro-2-methylphenylboronic acid price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | C2577 | 4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride) | 209919-30-2 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | C2577 | 4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride) | 209919-30-2 | 5g | $85 | 2026-04-30 | Buy |
| Usbiological | 270306 | 4-Chloro-2-methylphenylboronic acid Asreported | 209919-30-2 | 10g | $355 | 2026-06-03 | Buy |
| Usbiological | 270306 | 4-Chloro-2-methylphenylboronic acid Asreported | 209919-30-2 | 25g | $529 | 2026-06-03 | Buy |
| Usbiological | 270306 | 4-Chloro-2-methylphenylboronic acid Asreported | 209919-30-2 | 50g | $725 | 2026-06-03 | Buy |
4-Chloro-2-methylphenylboronic acid Chemical Properties, Uses, Production
Chemical Properties
White solid
Uses
suzuki reaction
Synthesis
14495-51-3
209919-30-2
The general procedure for the synthesis of 2-methyl-4-chlorophenylboronic acid from 2-bromo-5-chlorotoluene was as follows: first, 13.3 mL (0.1 mol) of 2-bromo-5-chlorotoluene was dissolved in 200 mL of anhydrous tetrahydrofuran (THF), followed by the addition of 27.7 mL (0.12 mol) of triisopropyl borate. After cooling the reaction mixture to -78°C in a dry ice-acetone bath, 48 mL (0.12 mol) of 2.5 M n-butyllithium (n-BuLi, dissolved in hexane) was added slowly dropwise over a period of 1 hour. After completion of the dropwise addition, the dry ice-acetone bath was removed. 150 mL of 3N hydrochloric acid (HCl) was added to the reaction mixture and the resulting mixture was stirred for 1 hour. Subsequently, the separated aqueous layer was extracted twice with 100 mL of ethyl acetate. The organic layers were combined, washed with saturated brine solution and dried with anhydrous magnesium sulfate (MgSO). After removal of the solvent by filtration under reduced pressure, the residue was recrystallized by 10% ethyl acetate/hexane solvent mixture to give 13.8 g (81% yield) of 2-methyl-4-chlorophenylboronic acid as a white solid. The product was characterized by 1H NMR (300 MHz, CDCl) with chemical shifts of δ 8.07 (dd, 1H, J = 5.7 Hz, 2.8 Hz), 7.28-7.26 (m, 2H), 2.76 (s, 3H).
References
[1] Patent: WO2005/123054, 2005, A1. Location in patent: Page/Page column 23
4-Chloro-2-methylphenylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
4-Chloro-2-methylphenylboronic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Maya High Purity Chemicals | +86 (573) 82222445 (0)18006601000 452520369 | sales@maya-r.com | China | 11693 | 57 |
View Latest Price from 4-Chloro-2-methylphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
|
1G | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2025-04-04 | 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
 |
2023-03-20 | 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
|
1kg | 98.0%min | 100kg | LY Global chemicals co.,ltd . |
-
- 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
- $0.00
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
- $0.00
- 98.0%min
- LY Global chemicals co.,ltd .
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