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4-CHLORO-2-METHYLPHENYLBORONIC ACID

4-CHLORO-2-METHYLPHENYLBORONIC ACID structure

CAS No.: 209919-30-2

Chemical Name:: 4-CHLORO-2-METHYLPHENYLBORONIC ACID

Synonyms: AKOS BRN-0229;4-CHLORO-2-METHYLPHENYL;2-Borono-5-chlorotoluene;4-chloro-o-tolylboronic acid;4-CHLORO-O-TOLUENEBORONIC ACID;4-Chloro-2-Methylphenylboronic;4-CHLORO-2-METHYLPHENYLBORONIC ACID;(4-chloro-2-methylphenyl)boronicaci;4-CHLORO-2-METHYLBENZENEBORONIC ACID;(2-Methyl-4-chlorophenyl)boronic acid

CBNumber:: CB0146513

Molecular Formula:: C7H8BClO2

Molecular Weight:: 170.4

MDL Number:: MFCD02683107

MOL File:: 209919-30-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:46

Product description	Number	Pack Size	Price
4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride)	C2577	1g	$29
4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride)	C2577	5g	$85
4-Chloro-2-methylphenylboronic acid	270306	10g	$355
4-Chloro-2-methylphenylboronicacid	C587458	250mg	$55
4-Chloro-2-methylphenylboronicacid,98% 98%	28643	1G	$11.2

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4-CHLORO-2-METHYLPHENYLBORONIC ACID Properties

Melting point	193-195°C
Boiling point	314.9±52.0 °C(Predicted)
Density	1.26±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Methanol
pka	8.47±0.58(Predicted)
form	powder to crystal
color	White to Almost white
InChIKey	SRXXSLUUAWHGBZ-UHFFFAOYSA-N
CAS DataBase Reference	209919-30-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H335-H315-H319

Precautionary statements

P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

26-36/37/39-36

HazardClass

IRRITANT

HS Code

29319090

NFPA 704

	0
2		0

4-CHLORO-2-METHYLPHENYLBORONIC ACID price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	C2577	4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride)	209919-30-2	1g	$29	2026-03-19	Buy
TCI Chemical	C2577	4-Chloro-2-methylphenylboronic Acid (contains varying amounts of Anhydride)	209919-30-2	5g	$85	2026-03-19	Buy
Usbiological	270306	4-Chloro-2-methylphenylboronic acid	209919-30-2	10g	$355	2021-12-16	Buy
TRC	C587458	4-Chloro-2-methylphenylboronicacid	209919-30-2	250mg	$55	2021-12-16	Buy
Chem-Impex	28643	4-Chloro-2-methylphenylboronicacid,98% 98%	209919-30-2	1G	$11.2	2021-12-16	Buy

Product number	Packaging	Price	Buy
C2577	1g	$29	Buy
C2577	5g	$85	Buy
270306	10g	$355	Buy
C587458	250mg	$55	Buy
28643	1G	$11.2	Buy

4-CHLORO-2-METHYLPHENYLBORONIC ACID Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

suzuki reaction

Synthesis

14495-51-3

209919-30-2

The general procedure for the synthesis of 2-methyl-4-chlorophenylboronic acid from 2-bromo-5-chlorotoluene was as follows: first, 13.3 mL (0.1 mol) of 2-bromo-5-chlorotoluene was dissolved in 200 mL of anhydrous tetrahydrofuran (THF), followed by the addition of 27.7 mL (0.12 mol) of triisopropyl borate. After cooling the reaction mixture to -78°C in a dry ice-acetone bath, 48 mL (0.12 mol) of 2.5 M n-butyllithium (n-BuLi, dissolved in hexane) was added slowly dropwise over a period of 1 hour. After completion of the dropwise addition, the dry ice-acetone bath was removed. 150 mL of 3N hydrochloric acid (HCl) was added to the reaction mixture and the resulting mixture was stirred for 1 hour. Subsequently, the separated aqueous layer was extracted twice with 100 mL of ethyl acetate. The organic layers were combined, washed with saturated brine solution and dried with anhydrous magnesium sulfate (MgSO). After removal of the solvent by filtration under reduced pressure, the residue was recrystallized by 10% ethyl acetate/hexane solvent mixture to give 13.8 g (81% yield) of 2-methyl-4-chlorophenylboronic acid as a white solid. The product was characterized by 1H NMR (300 MHz, CDCl) with chemical shifts of δ 8.07 (dd, 1H, J = 5.7 Hz, 2.8 Hz), 7.28-7.26 (m, 2H), 2.76 (s, 3H).

References

[1] Patent: WO2005/123054, 2005, A1. Location in patent: Page/Page column 23

4-CHLORO-2-METHYLPHENYLBORONIC ACID Preparation Products And Raw materials

Raw materials

Tetrahydrofuran Triisopropyl borate 1-Bromo-4-chloro-2-methylbenzene n-Butyllithium Hydrochloric acid

Water Hexane

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Preparation Products

3-(4-Chloro-2-methylphenyl)benzoic acid

4-CHLORO-2-METHYLPHENYLBORONIC ACID Suppliers

Global( 192)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29830	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Richest Group Ltd	18017061086	oled@richest-group.com	CHINA	5600	58
Antai Fine Chemical Technology Co.,Limited	18503026267	info@antaichem.com	CHINA	9636	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8828	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
AFINE CHEMICALS LIMITED	+86-0571-85134551	sales@afinechem.com	China	15083	58
Alfa Chemistry		info@alfa-chemistry.com	United States	2344	58

Supplier	Advantage
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Richest Group Ltd	58
Antai Fine Chemical Technology Co.,Limited	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58
AFINE CHEMICALS LIMITED	58
Alfa Chemistry	58

View Lastest Price from 4-CHLORO-2-METHYLPHENYLBORONIC ACID manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-04-04	4-CHLORO-2-METHYLPHENYLBORONIC ACID 209919-30-2	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2023-03-20	4-CHLORO-2-METHYLPHENYLBORONIC ACID 209919-30-2	US $0.00 / kg	1kg	98.0%min	100kg	LY Global chemicals co.,ltd .
2021-08-12	4-CHLORO-2-METHYLPHENYLBORONIC ACID 209919-30-2	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
US $0.00 / kg
98.0%min
LY Global chemicals co.,ltd .

4-CHLORO-2-METHYLPHENYLBORONIC ACID
209919-30-2
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

209919-30-2(4-CHLORO-2-METHYLPHENYLBORONIC ACID)Related Search:

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AKOS BRN-0229 4-CHLORO-O-TOLUENEBORONIC ACID 4-CHLORO-2-METHYLBENZENEBORONIC ACID 4-CHLORO-2-METHYLPHENYLBORONIC ACID 4-Chloro-2-Methylphenylboronic 4-chloro-o-tolylboronic acid 4-Chloro-2-methylphenylboronic acid ,98% 4-Chloro-2-Methylphenylboronic Acid (contains varying aMounts of Anhydride) 4-Chloro-2-methylbenzeneboronic Acid 4-Chloro-o-tolylboronic Acid 2-Borono-5-chlorotoluene (2-Methyl-4-chlorophenyl)boronic acid 4-CHLORO-2-METHYLPHENYL Boronic acid, B-(4-chloro-2-methylphenyl)- (4-chloro-2-methylphenyl)boronicaci 4-Chloro-2-methylphenylboronic acid - [C2228] 209919-30-2 C7H8ClBO2 Aryl Boronic acid Organoborons blocks BoronicAcids