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4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- structure

CAS No.: 1772823-37-6

Chemical Name:: 4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-

Synonyms: GSK-3 inhibitor 6;4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]-

CBNumber:: CB014685206

Molecular Formula:: C21H17FN4O2

Molecular Weight:: 376.38

MDL Number:

MOL File:: 1772823-37-6.mol

Last updated:2025-04-18 09:51:25

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4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Properties

Boiling point	565.3±50.0 °C(predicted)
Density	1.411±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	11.47±0.70(predicted)

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Chemical Properties, Uses, Production

Uses

GSK-3 inhibitor 6 (2) is a CNS penetrated GSK-3 inhibitor, with IC50 values of 29 nM and 24 nM for GSK-3α and GSK-3β, respectively[1].

References

[1] Surendra Reddy Gundam, et al. Synthesis and preliminary evaluation of novel PET probes for GSK-3 imaging. Sci Rep. 2024 Jul 10;14(1):15960. DOI:10.1038/s41598-024-65943-z

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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4-Pyridinecarboxamide, 2-[(cyclopropylcarbonyl)amino]-N-[4-(4-fluorophenyl)-3-pyridinyl]- GSK-3 inhibitor 6 1772823-37-6