ChemicalBook >> CAS DataBase List >>1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- structure

CAS No.: 2226227-77-4

Chemical Name:: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-

Synonyms: ML471;1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)-

CBNumber:: CB014686445

Molecular Formula:: C13H20N6O6S

Molecular Weight:: 388.4

MDL Number:

MOL File:: 2226227-77-4.mol

MSDS File:: SDS

Last updated:2025-04-17 18:22:24

Request For Quotation

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Properties

Boiling point	707.4±70.0 °C(predicted)
Density	1.93±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	9.15±0.70(predicted)

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Chemical Properties, Uses, Production

Uses

ML471 is an oral active parasite tyrosyl-tRNA synthetase (PfTyrRS) inhibitor and can be used for study of malaria[1].

References

[1] Stanley C. Xie, et al. A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo. Posted July 23, 2024.

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-[5-O-(aminosulfonyl)-β-D-ribofuranosyl]-3-(1-methylethyl)- ML471 2226227-77-4