ChemicalBook >> CAS DataBase List >>NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT
![NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT Structure](CAS/20150408/GIF/172733-42-5.gif)
- CAS No.
- 172733-42-5
- Chemical Name:
- NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT
- Synonyms
- LY 315920Na;LY 315920 sodium;Varespladib sodium;LY315920 sodiuM salt;VARESPLADIB SODIUM (LY315920 SODIUM SALT);NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT;[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid monosodium salt
- CBNumber:
- CB01475683
- Molecular Formula:
- C21H21N2NaO5
- Molecular Weight:
- 404.4
- MDL Number:
- MOL File:
- 172733-42-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:46
| form | Solid |
|---|---|
| color | Off-white to light yellow |
| FDA UNII | F6M52CDT0W |
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | XGA73342 | Varespladib sodium | 172733-42-5 | 50mg | $789 | 2026-06-05 | Buy |
| Biosynth | XGA73342 | Varespladib sodium | 172733-42-5 | 100mg | $1261 | 2026-06-05 | Buy |
| ChemScene | CS-0024932 | Varespladib sodium 98.83% | 172733-42-5 | 5mg | $119 | 2026-06-04 | Buy |
| ChemScene | CS-0024932 | Varespladib sodium 98.83% | 172733-42-5 | 10mg | $206 | 2026-06-04 | Buy |
| ChemScene | CS-0024932 | Varespladib sodium 98.83% | 172733-42-5 | 25mg | $412 | 2026-06-04 | Buy |
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT Chemical Properties,Uses,Production
Uses
Treatment of sepsis (sPLA2inhibitor).
in vivo
Varespladib sodium treatment inhibits human sPLA2-induced release of thromboxane A2 (TXA2) from isolated guinea pig lung bronchoalveolar lavage cells with an IC50 of 0.79 μM. And the ED50 for Varespladib sodium is 16.1 mg/kg[1].
| Animal Model: | Male Hartley guinea pigs (300-500 g)[1] |
| Dosage: | 3 mg/kg, 10 mg/kg, and 30 mg/kg |
| Administration: | Intravenous injection (Pharmacokinetic study) |
| Result: | Consistent inhibition of sPLA2 activity in BAL fluid was observed. Reduced the human sPLA2-induced generation of TXA2 on BAL cells from guinea pigs. |
IC 50
sPLA2: 9 nM (IC50)
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT Preparation Products And Raw materials
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT Suppliers
Global( 10)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| NCE Biomedical Co.,Ltd. | 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 | China | 1490 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Lanzhou Angeli Biochemical Technology Co., Ltd. | 0931-8235634 13321316780 | 1455540579@qq.com | China | 957 | 55 |
| ChengDu TongChuangYuan Pharmaceutical Co.Ltd | 028-83379370 13880556291 | tcy@tcypharm.com | China | 8696 | 58 |
| Jinan Kabotang Biological Technology Co.,Ltd. | 0531-61320525 15866703830 | figo.gao@foxmail.com | China | 7600 | 58 |
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9867 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
172733-42-5(NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT)Related Search:
NATRIUM[(1-BENZYL-2-ETHYL-3-OXAMOYLINDOOL-4-YL)OXY]ACETAAT
LY315920 sodiuM salt
[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid monosodium salt
LY 315920 sodium
LY 315920Na
Varespladib sodium
VARESPLADIB SODIUM (LY315920 SODIUM SALT)
172733-42-5
C21H20N2O5Na
