ChemicalBook >> CAS DataBase List >>DESTRUXIN A
DESTRUXIN A
- CAS No.
- 6686-70-0
- Chemical Name:
- DESTRUXIN A
- Synonyms
- 3-Ethenylcyclo(D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-βAla-);DESTRUXIN A;destruxin A from metarhizium anisopliae;Destruxin A from Metarrhizium anisopliae;Destruxin A, 98%, from Metarhizium anisopliae;Destruxin A from Metarrhizium anisopliae;Destruxin A from Metarrhizium anisopliae >=98% (HPLC);Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl];N-[N-[(R)-2-Hydroxy-1-oxo-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone;N-[N-[(2R)-1-Oxo-2-hydroxy-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
- CBNumber:
- CB0148047
- Molecular Formula:
- C29H47N5O7
- Molecular Weight:
- 577.71
- MDL Number:
- MFCD01736100
- MOL File:
- 6686-70-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 17:21:55
| Melting point | 188-189 °C |
|---|---|
| Boiling point | 875.6±65.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Acetonitrile: Soluble; DMF: Soluble; DMSO: Soluble |
| form | A powder |
| pka | 13.53±0.70(Predicted) |
| color | White to off-white |
| biological source | Metarrhizium anisopliae |
| InChIKey | XIYSEKITPHTMJT-UTJJDKHZSA-N |
| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CC=C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C1=O |
| EWG's Food Scores | 1 |
| FDA UNII | 255H1K2LFG |
| UNSPSC Code | 12352200 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-48 | |||||||||
| Safety Statements | 26-36-45 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | HH1500000 | |||||||||
| HS Code | 2933790090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
DESTRUXIN A price More Price(21)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D4921 | Destruxin A from Metarrhizium anisopliae ≥98% (HPLC) | 6686-70-0 | 1mg | $1030 | 2026-04-30 | Buy |
| Cayman Chemical | 20428 | Destruxin A ≥96% | 6686-70-0 | 1mg | $590 | 2026-04-30 | Buy |
| Cayman Chemical | 20428 | Destruxin A ≥96% | 6686-70-0 | 5mg | $2064 | 2026-04-30 | Buy |
| Cayman Chemical | 20428 | Destruxin A ≥96% | 6686-70-0 | 5 mg | $2009 | 2024-03-01 | Buy |
| Biosynth | BD162717 | Destruxin A | 6686-70-0 | 1mg | $960.82 | 2026-06-04 | Buy |
DESTRUXIN A Chemical Properties, Uses, Production
Uses
Destruxin A from Metarrhizium anisopliae has been used for immersion and inoculation bioassay in Rhipicephalus (Boophilus) microplus. It has been used as a transport inhibitor in Drosophila melanogaster.
Biochem/physiol Actions
Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects. May suppress the insect immune response. Possesses an inhibitory activity on leukemic cell proliferation, decreasing the number of cells in G2/M phase. It is virustatic against arboviruses.
in vivo
Destruxin A (injection; 86 μM; single dose) can specifically inhibit the humoral immune response of Drosophila melanogaster, making the flies more susceptible to bacterial infections[3].
DESTRUXIN A Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 42)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 | shenlinxing@macklin.cn | China | 15775 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Qingdao IniKem BioPharmaTech Co.,Ltd | 0532-58268781 18561687109 | sales@inikem.com | China | 299 | 55 |
| Alabiotech Inc. | 001-619-354-5251 | sales@alabiotech-e.com | United States | 972 | 60 |
| Alpha Biopharmaceuticals Co., Ltd | 0411-39042497 | sales@alphabiopharm.com | China | 1951 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19904 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
6686-70-0 (DESTRUXIN A) Related Search:
N-[N-[(2R)-1-Oxo-2-hydroxy-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
N-[N-[(R)-2-Hydroxy-1-oxo-4-pentenyl]-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-]-β-alanine lactone
Destruxin A from Metarrhizium anisopliae
Destruxin A, 98%, from Metarhizium anisopliae
DESTRUXIN A
destruxin A from metarhizium anisopliae
Cyclo[N-methyl-L-alanyl-β-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl]
Destruxin A from Metarrhizium anisopliae >=98% (HPLC)
Destruxin A from Metarrhizium anisopliae
3-Ethenylcyclo(D-Lac-L-Pro-L-Ile-N-methyl-L-Val-N-methyl-L-Ala-βAla-)
6686-70-0
C29H47N5O7
Apoptosis and Cell Cycle
BioChemical
Cell Biology
Cell Signaling and Neuroscience
Cell Cycle
Cell Cycle Regulators
Apoptosis and Cell Cycle
Cell Cycle
Cell Cycle Regulators
