2-Bromo-5-hydroxymethyl-anisole
- CAS No.
- 17100-64-0
- Chemical Name:
- 2-Bromo-5-hydroxymethyl-anisole
- Synonyms
- (4-broMo-3-Methoxyphenyl)Methanol;2-Bromo-5-hydroxymethyl-anisole;4-Bromo-3-methoxybenzyl alcohol;Benzyl alcohol, 4-bromo-3-methoxy-;Benzenemethanol, 4-bromo-3-methoxy-
- CBNumber:
- CB01519637
- Molecular Formula:
- C8H9BrO2
- Molecular Weight:
- 217.06
- MDL Number:
- MFCD11053671
- MOL File:
- 17100-64-0.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2909498090 |
2-Bromo-5-hydroxymethyl-anisole price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| AstaTech | 63215 | 2-BROMO-5-HYDROXYMETHYL-ANISOLE 97% | 17100-64-0 | 1G | $63 | 2026-04-30 | Buy |
| AstaTech | 63215 | 2-BROMO-5-HYDROXYMETHYL-ANISOLE 97% | 17100-64-0 | 5G | $237 | 2026-04-30 | Buy |
| AstaTech | 63215 | 2-BROMO-5-HYDROXYMETHYL-ANISOLE 97% | 17100-64-0 | 25G | $889 | 2026-04-30 | Buy |
| Apolloscientific | OR400176 | 4-Bromo-3-methoxybenzyl alcohol 98% | 17100-64-0 | 250mg | $25 | 2026-06-04 | Buy |
| Apolloscientific | OR400176 | 4-Bromo-3-methoxybenzyl alcohol 98% | 17100-64-0 | 1g | $69 | 2026-06-04 | Buy |
2-Bromo-5-hydroxymethyl-anisole Chemical Properties, Uses, Production
Synthesis
6971-51-3
17100-64-0
The general procedure for the synthesis of 2-bromo-5-hydroxymethyl anisole from m-methoxybenzyl alcohol was as follows: to a solution of 3-methoxybenzyl alcohol (20.0 g, 145 mmol) in tetrahydrofuran (THF, 400 mL) was added N-bromosuccinimide (NBS, 26 g, 146 mmol). The reaction mixture was stirred at room temperature for 8 hours. After the reaction was completed, ether (500 mL) was added to dilute and the mixture was washed with deionized water (3 x 100 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to afford 2-bromo-5-hydroxymethyl anisole (31.2 g, 99% yield), and the product was used directly in the next reaction without further purification.
References
[1] Patent: US9725406, 2017, B1. Location in patent: Page/Page column 7-8
[2] Tetrahedron, 2005, vol. 61, # 49, p. 11692 - 11696
[3] Patent: US2018/208604, 2018, A1. Location in patent: Paragraph 0201-0203
[4] Patent: US2010/4159, 2010, A1. Location in patent: Page/Page column 59; 64
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 3, p. 1010 - 1014
2-Bromo-5-hydroxymethyl-anisole Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromo-5-hydroxymethyl-anisole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9509 | 58 |
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| Changzhou Tianrui Pharmaceutical Technology Co., Ltd. | 0519-85386832 13382812559 | sales@cztrchem.com | China | 1211 | 56 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
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