Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>4-Bromo-3-methoxybenzoic acid

4-Bromo-3-methoxybenzoic acid

4-Bromo-3-methoxybenzoic acid Structure
4-Bromo-3-methoxybenzoic acid structure
CAS No.
56256-14-5
Chemical Name:
4-Bromo-3-methoxybenzoic acid
Synonyms
4-BROMO-3-METHOXYBEN;2-Bromo-5-carboxyanisole;4-Bromo-3-methoxybenzoic acid;3-methoxy-4-bromobenzoic acid;Benzoic acid, 4-bromo-3-methoxy-;4-BROMO-3-METHOXYBENZOIC ACID 98;4-Bromo-3-methoxybenzoic acid 98%;Daridorexant Hydrochloride Impurity 153;2-Bromo-5-carboxyanisole, 4-Bromo-m-anisic acid;4-Bromo-3-methoxybenzoic acid ISO 9001：2015 REACH
CBNumber:
CB3500440
Molecular Formula:
C8H7BrO3
Molecular Weight:
231.04
MDL Number:
MFCD08436017
MOL File:
56256-14-5.mol
MSDS File:
SDS
Last updated:2026-05-28 02:30:47
Request For Quotation

4-Bromo-3-methoxybenzoic acid Properties

Melting point 221-224
Boiling point 333.7±27.0 °C(Predicted)
Density 1.625±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form crystalline solid
pka 3.85±0.10(Predicted)
color Off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
RIDADR  UN2811
Hazard Note  Irritant/Keep Cold
HS Code  2918999090

4-Bromo-3-methoxybenzoic acid price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 63219 4-BROMO-3-METHOXYBENZOIC ACID 97% 56256-14-5 25G $57 2026-04-30 Buy
Activate Scientific AS32408 4-Bromo-3-methoxybenzoic acid 97% 56256-14-5 5g $31 2026-06-04 Buy
Activate Scientific AS32408 4-Bromo-3-methoxybenzoic acid 97% 56256-14-5 25g $109 2026-06-04 Buy
Activate Scientific AS32408 4-Bromo-3-methoxybenzoic acid 97% 56256-14-5 100g $328 2026-06-04 Buy
AK Scientific X2799 4-Bromo-3-methoxybenzoic acid 98%(HPLC) 56256-14-5 1g $16 2026-06-04 Buy
Product number Packaging Price Buy
63219 25G $57 Buy
AS32408 5g $31 Buy
AS32408 25g $109 Buy
AS32408 100g $328 Buy
X2799 1g $16 Buy

4-Bromo-3-methoxybenzoic acid Chemical Properties,Uses,Production

Uses

4-Bromo-3-methoxybenzoic acid is an important fine organic chemical product, widely used in pharmaceuticals, pesticides, fragrances, petrochemicals and other fields. With the development of science and technology, it is playing an increasingly important role in the synthesis of drugs, liquid crystals and other fields.

Chemical Properties

off-white powder

Synthesis

METHYL 4-BROMO-3-METHOXYBENZOATE

17100-63-9

4-Bromo-3-methoxybenzoic acid

56256-14-5

General procedure for the synthesis of 4-bromo-3-methoxybenzoic acid from methyl 4-bromo-3-methoxybenzoate: To a stirred solution of methyl 4-bromo-3-methoxybenzoate (11.2 g) in THF (130 mL) was added methanol (45 mL), water (45 mL), and a 1 M aqueous lithium hydroxide (140 mL) in sequence. The reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the solvent was removed by rotary evaporator under reduced pressure. Water was added to the residue, followed by the dropwise addition of 1 N hydrochloric acid while cooling in an ice bath until the pH of the mixture reached 4. The precipitated solid product was collected by diafiltration, washed with water and dried under reduced pressure to give 10.1 g of the title compound 4-bromo-3-methoxybenzoic acid, which was used in the subsequent reaction without further purification.1H-NMR (300 MHz. DMSO-d6): δ[ppm] = 3.87 (s, 3H), 7.42 (dd, 1H), 7.50 (d, 1H), 7.68 (d, 1H), 13.21 (br s, 1H).

References

[1] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 2267 - 2273
[2] Patent: US2003/45557, 2003, A1
[3] Patent: WO2011/64328, 2011, A1. Location in patent: Page/Page column 79-80
[4] Patent: WO2012/143329, 2012, A1. Location in patent: Page/Page column 89
[5] Patent: WO2013/87579, 2013, A1. Location in patent: Page/Page column 96; 97

4-Bromo-3-methoxybenzoic acid Preparation Products And Raw materials

Raw materials

Methyl 4-bromo-3-methoxybenzoate Methanol Water Lithium hydroxide Tetrahydrofuran

Preparation Products

4-Bromo-3-methoxybenzoic acid Suppliers

Global( 165)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Harvest Chemical Industrial Co., Ltd. 15721252604 17321035817 sales@harvest-chem.com China 2829 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Supplier Advantage
J & K SCIENTIFIC LTD. 76
PharmaBlock Sciences (Nanjing),Inc. 55
Energy Chemical 61
Wuhan Chemwish Technology Co., Ltd 56
Beijing Ouhe Technology Co., Ltd 60
Accela ChemBio Co.,Ltd. 64
Shanghai Harvest Chemical Industrial Co., Ltd. 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Shanghai yirong biology science and technology co., ltd 60

View Lastest Price from 4-Bromo-3-methoxybenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-3-methoxybenzoic acid pictures 2019-07-06 4-Bromo-3-methoxybenzoic acid
56256-14-5
 $1.00 1KG 98% 200kg Career Henan Chemical Co

4-Bromo-3-methoxybenzoic acid Spectrum

4-Bromo-3-methoxybenzoic acid(56256-14-5)1HNMR

56256-14-5(4-Bromo-3-methoxybenzoic acid)Related Search:

4-Bromo-3,5-dimethoxybenzoic acid Methyl 2-bromo-5-methoxybenzoate Methyl 4-bromo-3-methoxybenzoate 2,4-Dibromo-3-(difluoromethoxy)benzoic acid 4-Amino-5-bromo-2-methoxybenzenecarboxylic acid
2-Bromo-5-methoxybenzoic acid 3-Bromo-4-methoxybenzoic acid Methyl 4-bromo-2-methoxybenzoate 98 3-Bromo-2-methoxybenzoic acid ethyl 3-bromo-5-methoxybenzoate
Methyl 4-acetamido-5-bromo-2-methoxybenzoate 5-Bromo-2-methoxybenzoic acid 4-Bromo-3-methoxybenzoic acid tert-Butyl 4-bromo-3-methoxybenzoate 98 Methyl 3-bromo-4-methoxybenzoate 98
tert-Butyl 3-benzyloxy-4-bromobenzoate 3-(Benzyloxy)-4-bromobenzoic acid 98 Methyl 3-(benzyloxy)-4-bromobenzoate 98

1of4

2-Bromo-5-carboxyanisole, 4-Bromo-m-anisic acid 4-Bromo-3-methoxybenzoic acid 2-Bromo-5-carboxyanisole 4-BROMO-3-METHOXYBENZOIC ACID 98 4-Bromo-3-methoxybenzoic acid 98% 4-BROMO-3-METHOXYBEN Benzoic acid, 4-bromo-3-methoxy- 4-Bromo-3-methoxybenzoic acid ISO 9001：2015 REACH 3-methoxy-4-bromobenzoic acid Daridorexant Hydrochloride Impurity 153 56256-14-5 Acids & Esters Anisoles, Alkyloxy Compounds & Phenylacetates Bromine Compounds blocks Bromides Carboxes