P-nitrophenyl butyrate
- CAS No.
- 2635-84-9
- Chemical Name:
- P-nitrophenyl butyrate
- Synonyms
- PNP-Butyrate;4-Nitrophenol butyrate;P-NITROPHENYL BUTYRATE;4-NITROPHENYL BUTYRATE;PARA-NITROPHENYLBUTYRATE;(4-nitrophenyl) butanoate;4-Nitrophenyl butyrate >=98%;BUTYRIC ACID 4-NITROPHENYL ESTER;Butanoic acid p-nitrophenyl ester;Butanoic acid, 4-nitrophenyl ester
- CBNumber:
- CB0202840
- Molecular Formula:
- C10H11NO4
- Molecular Weight:
- 209.2
- MDL Number:
- MFCD00047734
- MOL File:
- 2635-84-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 184-185 °C |
|---|---|
| Density | 1.19 g/mL at 20 °C(lit.) |
| storage temp. | -20°C |
| solubility | chloroform: 0.1 g/mL, clear, faintly yellow |
| form | A neat oil |
| color | Colorless to light yellow |
| BRN | 1879729 |
| InChI | InChI=1S/C10H11NO4/c1-2-3-10(12)15-9-6-4-8(5-7-9)11(13)14/h4-7H,2-3H2,1H3 |
| InChIKey | DVDUMIQZEUTAGK-UHFFFAOYSA-N |
| SMILES | C(OC1=CC=C([N+]([O-])=O)C=C1)(=O)CCC |
| FDA UNII | 42RWS6BQC4 |
| UNSPSC Code | 12352204 |
| NACRES | NA.83 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H317 |
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P362+P364 |
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 43 |
| Safety Statements | 36/37 |
| WGK Germany | 3 |
| HS Code | 29156000 |
| Storage Class | 10 - Combustible liquids |
| Hazard Classifications | Skin Sens. 1 |
P-nitrophenyl butyrate price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N9876 | 4-Nitrophenyl butyrate ≥98% | 2635-84-9 | 1g | $85.6 | 2026-04-30 | Buy |
| Sigma-Aldrich | N9876 | 4-Nitrophenyl butyrate ≥98% | 2635-84-9 | 5g | $305 | 2026-04-30 | Buy |
| TCI Chemical | N1316 | 4-Nitrophenyl Butyrate min. 97.0 % | 2635-84-9 | 1G | $59 | 2026-04-30 | Buy |
| TCI Chemical | N1316 | 4-Nitrophenyl Butyrate min. 97.0 % | 2635-84-9 | 5G | $204 | 2026-04-30 | Buy |
| Cayman Chemical | 25439 | 4-Nitrophenyl Butyrate ≥95% | 2635-84-9 | 1g | $54 | 2026-04-30 | Buy |
P-nitrophenyl butyrate Chemical Properties, Uses, Production
Description
P-nitrophenyl butyrate also kown as 4-nitrophenyl butyrate, is a probe for lipase activity. It is hydrolyzed by lipase in the water ambient condition, giving rise to p-nitrophenol and butyric acid. P-nitrophenol actually occurs in the anionic form, p-nitrophenolate, giving a yellowish coloration and absorbing light at 410 nm in an alkaline buffer such as Tris-HCl pH 7.5.
Uses
4-Nitrophenyl butyrate is a substrate for esterase, and lipase enzyme. Hydrolysis of 4-nitrophenyl butyrate by these enzymes releases the chromophore, 4-nitrophenolate which is spectrophotometrically analysed at 415 nm.
Definition
ChEBI: P-nitrophenyl butyrate is a butyrate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of butyric acid. It is a butyrate ester and a C-nitro compound. It is functionally related to a 4-nitrophenol.
References
[1] POHANKA M. Biosensors and Bioassays Based on Lipases, Principles and Applications, a Review.[J]. Molecules, 2019. DOI:10.3390/molecules24030616.
[2] WENTING SHANG. Enzymatic hydrolysis of p-nitrophenyl butyrate in CO2-based micelle systems[J]. Journal of chemical technology and biotechnology, 2013, 89 9: 1324-1329. DOI:10.1002/jctb.4246.
[3] SIGRUN H. STERRI Frode F Bjrn A Johnsen. A radiochemical assay method for carboxylesterase, and comparison of enzyme activity towards the substrates methyl [1-14C] butyrate and 4-nitrophenyl butyrate[J]. Biochemical pharmacology, 1985, 34 15: Pages 2779-2785. DOI:10.1016/0006-2952(85)90579-9.
[4] BISHNU PRASAD PANDEY. Bergenia pacumbis from Nepal, an astonishing enzymes inhibitor.[J]. BMC Complementary Medicine and Therapies, 2020: 198. DOI:10.1186/s12906-020-02989-2.
P-nitrophenyl butyrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29977 | 65 |
| Nanjing Dulai Biotechnology Co., Ltd. | 025-84699383-8003;025-846993838003-8003 18013301590 | njduly@126.com | China | 3293 | 55 |
| Wuxi Zhangkun Biochemical Technology Co., Ltd. | +86 0510-85629785 | China | 2321 | 58 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| ShangHai D&B Biological Science and Technology Co.Ltd | 400-008-9730,021-54359730 400-008-9730 | info@chemxyz.com | China | 3642 | 60 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632; | sales@reading-chemicals.com | China | 15165 | 58 |
View Latest Price from P-nitrophenyl butyrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | P-nitrophenyl butyrate
2635-84-9
|
1KG | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-01 | P-NITROPHENYL BUTYRATE
2635-84-9
|
$1.00 | 1KG | 95-99% | 1ton | Career Henan Chemical Co |
-
- P-nitrophenyl butyrate
2635-84-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- P-NITROPHENYL BUTYRATE
2635-84-9
- $1.00
- 95-99%
- Career Henan Chemical Co
