4-Nitrophenyl acetate
- CAS No.
- 830-03-5
- Chemical Name:
- 4-Nitrophenyl acetate
- Synonyms
- P-NITROPHENYL ACETATE;4-Nitropheyl acetate;NSC 2633;p-nitrophenyl;4-Nitrophenylacetat;p-Acetoxynitrobenzen;p-nitrophenolacetate;Lecithin Impurity 14;p-Nitrobenzeneacetate;p-Nitrophenol acetate
- CBNumber:
- CB5200306
- Molecular Formula:
- C8H7NO4
- Molecular Weight:
- 181.15
- MDL Number:
- MFCD00007326
- MOL File:
- 830-03-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 75-77 °C (lit.) |
|---|---|
| Boiling point | 314.24°C (rough estimate) |
| Density | 1.4283 (rough estimate) |
| vapor pressure | 1.28Pa at 20℃ |
| refractive index | 1.5468 (estimate) |
| storage temp. | -20°C |
| solubility | 0.53g/l |
| form | Powder |
| color | Green |
| Water Solubility | Insoluble in water. |
| BRN | 515874 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChI | 1S/C8H7NO4/c1-6(10)13-8-4-2-7(3-5-8)9(11)12/h2-5H,1H3 |
| InChIKey | QAUUDNIGJSLPSX-UHFFFAOYSA-N |
| SMILES | [N+](=O)([O-])c1ccc(cc1)OC(=O)C |
| LogP | 1.58 at 25℃ and pH6.83 |
| CAS DataBase Reference | 830-03-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | I902J0QH9S |
| EPA Substance Registry System | Acetic acid, 4-nitrophenyl ester (830-03-5) |
| UNSPSC Code | 12352204 |
| NACRES | NA.32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS03,GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H272-H317-H318 | |||||||||
| Precautionary statements | P210-P220-P261-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | F,C | |||||||||
| Risk Statements | 11-34 | |||||||||
| Safety Statements | 24/25-45-36/37/39-26-16 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AJ1150000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29153900 | |||||||||
| Storage Class | 5.1B - Oxidizing hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Ox. Sol. 3 Skin Sens. 1 |
|||||||||
| Toxicity | LD50 ivn-mus: 180 mg/kg CSLNX* NX#00217 | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Nitrophenyl acetate price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N8130 | 4-Nitrophenyl acetate esterase substrate | 830-03-5 | 5g | $73.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | N8130 | 4-Nitrophenyl acetate esterase substrate | 830-03-5 | 10g | $90.8 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.43075 | 4-Nitrophenyl acetate for synthesis | 830-03-5 | 25g | $176 | 2026-04-30 | Buy |
| TCI Chemical | A0040 | 4-Nitrophenyl Acetate >98.0%(GC) | 830-03-5 | 25g | $146 | 2026-04-30 | Buy |
| TCI Chemical | A0040 | 4-Nitrophenyl Acetate >98.0%(GC) | 830-03-5 | 100g | $480 | 2026-04-30 | Buy |
4-Nitrophenyl acetate Chemical Properties,Uses,Production
Chemical Properties
off-white or beige powder
Uses
4-Nitrophenyl Acetate have been used as a substrate to study for the enzymatic activity of Carbonic Anhydrase III isolated from bovine skeletal muscle.
Uses
4-Nitrophenyl acetate is used with iodoacetic acid for reductive cleavage of methionine-containing peptides. It is also used as a substrate that has been used in assays for esterase and lipase activity. Inorganic complexes have been evaluated for their methanolysis or hydrolysis activity using p-nitrophenyl acetate.
Definition
ChEBI: An acetate ester resulting from the formal condensation of the hydroxy group of 4-nitrophenol with the carboxy group of acetic acid.
Synthesis Reference(s)
Synthesis, p. 991, 1981 DOI: 10.1055/s-1981-29674
Safety Profile
Poison by intravenous route. Whenheated to decomposition it emits toxic fumes of NOx.
Purification Methods
Recrystallise the ester from absolute EtOH [Moss et al. J Am Chem Soc 108 5520 1986]. [Beilstein 6 IV 1298.]
4-Nitrophenyl acetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sichuan Kulinan Technology Co., Ltd | 400-1166-196 18981987031 | cdhxsj@163.com | China | 11674 | 57 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
View Lastest Price from 4-Nitrophenyl acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | 4-NITROPHENYL ACETATE
830-03-5
|
$75.00-100.00 | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2019-07-10 | 4-NITROPHENYL ACETATE
830-03-5
|
$1.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 4-NITROPHENYL ACETATE
830-03-5
- $75.00-100.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 4-NITROPHENYL ACETATE
830-03-5
- $1.00
- 99%
- Career Henan Chemical Co
