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N-BOC-3-Aminopiperidine

N-BOC-3-Aminopiperidine structure

CAS No.: 184637-48-7

Chemical Name:: N-BOC-3-Aminopiperidine

Synonyms: TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE;1-BOC-3-AMINOPIPERIDINE;Azacycloheptane, 3-amino-1-t-butoxycarbonyl-;N-BOC-3-AMinopiperid;3-AMINO-1-N-BOC-PIPERIDINE;3-Amino-1-Boc-piperidine,97%;N-BOC-3-Aminopiperidine USP/EP/BP;1-BOC-3-AMINOPIPERIDINE HYDROCHLORIDE;3-AMINO-1-TERTBUTOXYCARBONYL-PIPERIDINE;3-amino-1-piperidinecarboxylic acid tert-butyl ester

CBNumber:: CB0211321

Molecular Formula:: C10H20N2O2

Molecular Weight:: 200.28

MDL Number:: MFCD01861219

MOL File:: 184637-48-7.mol

Last updated:2025-07-24 18:13:40

Product description	Number	Pack Size	Price
3-Amino-1-tert-butoxycarbonylpiperidine >97.0%(GC)(T)	A2314	1g	$27
3-Amino-1-tert-butoxycarbonylpiperidine >97.0%(GC)(T)	A2314	5g	$107
1-Boc-3-aminopiperidine	B621143	500mg	$60
1-Boc-3-aminopiperidine citric acid salt	228677	250mg	$273
1-Boc-3-aminopiperidine	FB31217	100g	$290
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N-BOC-3-Aminopiperidine Properties

Melting point	181-182°C
Boiling point	277.3±33.0 °C(Predicted)
Density	1.02
refractive index	1.4710-1.4750
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	clear liquid
pka	10.35±0.20(Predicted)
color	Colorless to Light yellow
optical activity	Consistent with structure
Water Solubility	Slightly soluble in water.
Sensitive	Air Sensitive
InChI	InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3
InChIKey	AKQXKEBCONUWCL-UHFFFAOYSA-N
SMILES	N1(C(OC(C)(C)C)=O)CCCC(N)C1
CAS DataBase Reference	184637-48-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes

Xn,Xi

Risk Statements

22-36/37/38-51

Safety Statements

26-39-37

HazardClass

IRRITANT

HS Code

29335990

NFPA 704

	0
2		0

N-BOC-3-Aminopiperidine price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	A2314	3-Amino-1-tert-butoxycarbonylpiperidine >97.0%(GC)(T)	184637-48-7	1g	$27	2025-07-31	Buy
TCI Chemical	A2314	3-Amino-1-tert-butoxycarbonylpiperidine >97.0%(GC)(T)	184637-48-7	5g	$107	2025-07-31	Buy
TRC	B621143	1-Boc-3-aminopiperidine	184637-48-7	500mg	$60	2021-12-16	Buy
Usbiological	228677	1-Boc-3-aminopiperidine citric acid salt	184637-48-7	250mg	$273	2021-12-16	Buy
Biosynth Carbosynth	FB31217	1-Boc-3-aminopiperidine	184637-48-7	100g	$290	2021-12-16	Buy

Product number	Packaging	Price	Buy
A2314	1g	$27	Buy
A2314	5g	$107	Buy
B621143	500mg	$60	Buy
228677	250mg	$273	Buy
FB31217	100g	$290	Buy

N-BOC-3-Aminopiperidine Chemical Properties,Uses,Production

Uses

3-Amino-1-Boc-piperidine is used as an organic chemical synthesis intermediate.

Synthesis

54012-73-6

24424-99-5

144243-24-3

184637-48-7

In a 200 mL four-necked flask equipped with a stirrer, pH sensor, and two dropping funnels, 90 g of ethanol and 10.0 g (0.1 mol) of 3-aminopiperidine were added and stirred at 10 to 15 °C. 21.8 g (0.1 mol) di-tert-butyl dicarbonate was slowly added through one dropping funnel while 17.6 g (0.11 mol) 25% aqueous sodium hydroxide was added dropwise through the other dropping funnel, and the dropping rate was controlled to maintain the pH of the reaction system between 11.8 and 12.2. The titration process was completed in about 1 hour. Upon completion of the reaction, the composition of the reaction mixture was analyzed and confirmed to contain 6% unreacted 3-aminopiperidine, 91.5% of the target product 3-amino-1-tert-butoxycarbonylpiperidine and 1.1% of the by-product 3-tert-butoxycarbonylaminopiperidine.

References

[1] Patent: EP1460061, 2004, A1. Location in patent: Page 6-7

N-BOC-3-Aminopiperidine synthesis

Synthesis of N-BOC-3-Aminopiperidine from 1-BENZYL-3-N-BOC-AMINOPIPERIDINE

N-BOC-3-Aminopiperidine Preparation Products And Raw materials

Raw materials

(9H-FLUOREN-9-YL)METHYL 3-((TERT-BUTOXYCARBONYL)AMINO)PIPERIDINE-1-CARBOXYLATE Benzyl 3-(tert-Butoxycarbonylamino)piperidine-1-carboxylate 3-(BOC-AMINO)PYRIDINE 1-BENZYL-3-N-BOC-AMINOPIPERIDINE 3-Aminopyridine

3-AMINOPIPERIDINE Di-tert-butyl dicarbonate Sodium hydroxide Ethanol DL-Glutamic acid

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Preparation Products

1-BOC-3-AMINOPIPERIDINE 1-Benzyl-3-aminopiperidine 1-(Methylsulfonyl)-3-piperidinaMine Trifluoroacetate

N-BOC-3-Aminopiperidine Suppliers

Global( 290)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29852	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2176	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10239	58

Supplier	Advantage
Chembon Pharmaceutical Co., Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Accela ChemBio Inc.	58
Changzhou Ditong Chemical Co.,Ltd	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Hubei Ipure Biology Co., Ltd	58

View Lastest Price from N-BOC-3-Aminopiperidine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2021-08-12	N-BOC-3-Aminopiperidine 184637-48-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2021-07-02	3-Amino-1-tert-butoxycarbonylpiperidine 184637-48-7	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	N-BOC-3-Aminopiperidine 184637-48-7	US $1.00 / KG	1KG	98%	500kg	Career Henan Chemical Co

N-BOC-3-Aminopiperidine
184637-48-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

3-Amino-1-tert-butoxycarbonylpiperidine
184637-48-7
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

N-BOC-3-Aminopiperidine
184637-48-7
US $1.00 / KG
98%
Career Henan Chemical Co

N-BOC-3-Aminopiperidine Spectrum

N-BOC-3-Aminopiperidine(184637-48-7)¹HNMR

184637-48-7(N-BOC-3-Aminopiperidine)Related Search:

4-Amino-1-Boc-piperidine tert-Butanol Tris(trimethylsilyl)phosphate 6-Aminocaproic acid tert-Butyl peroxyacetate

BUTYL OLEATE 3-Aminopyridine Glycine Diethylene glycol monobutyl ether 1-Aminopiperidine

Butyl acetate Cyhalofop-butyl Haloperidol ALTRENOGEST Buprofezin

Tris(hydroxymethyl)aminomethane N-BOC-1,2,3,6-TETRAHYDROPYRIDINE N-Boc-4-iodopiperidine

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3-AMINO-1-BOC-PIPERIDINE X HCL N-Boc-3-piperidinamine 1-Boc-3-aminopiperidinecitricacid 1-BOC-3-aminopiperdine 1-Boc-3-aminopiperidine ,97% N-BOC-3-AMinopiperidine(HCl) N-BOC-3-AMinopiperid 3-Amino-1-Boc-piperidine tert-Butyl 3-Amino-1-piperidinecarboxylate 3-Amino-1-piperidinecarboxylic Acid tert-Butyl Ester 3(R)-[(tert-butoxycarbonyl)-aMino]piperidine tert-Butyl 3-aminopiperidine-1-carboxylate, 3-Amino-1-(tert-butoxycarbonyl)piperidine 3-amino-1-piperidinecarboxylic acid tert-butyl ester Azacycloheptane, 3-amino-1-t-butoxycarbonyl- 3-Amino-1-Boc-piperidine,97% TERT-BUTYL 3-AMINOPIPERIDINE-1-CARBOXYLATE N-1-BOC-3-AMINOPIPERIDINE N-BOC-3-AMINOPIPERIDINE DL-3-AMINO-1-N-BOC-PIPERIDINE (+/-)-1-BOC-3-AMINO-PIPERIDINE 1-BOC-3-AMINOPIPERIDINE 1-BOC-3-AMINOPIPERIDINE CITRIC ACID SALT 1-N-BOC-3-AMINOPIPERIDINE 1-PIPERIDINECARBOXYLIC ACID, 3-AMINO-, 1,1-DIMETHYLETHYL ESTER 3-AMINOPIPERIDINE, 1-BOC PROTECTED HYDROCHLORIDE 3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-AMINOPIPERIDINE, N1-BOC PROTECTED 3-AMINO-1-TERT-BUTOXYCARBONYL-PIPERIDINE HCL 3-AMINO-1-TERT-BUTOXYCARBONYL-PIPERIDINE HYDROCHLORIDE 3-AMINO-1-TERTBUTOXYCARBONYL-PIPERIDINE (+/-)-3-AMINO-1-BOC-PIPERIDINE 3-AMINO-1-BOC-PIPERIDINE HCL (+/-)-3-AMINO-1-N-BOC-PIPERIDINE 3-AMINO-1-N-BOC-PIPERIDINE (+/-)-3-AMINO-1-N-BOC-PIPERIDINE HYDROCHLORIDE 3-AMINO-1-N-BOC-PIPERIDINE HYDROCHLORIDE 3-AMINO-4-BOC-PIPERIDINE 1-Boc-3-amniopiperidine 3-Aminopiperidine, N1-BOC protected 97% Boc-3-Aminopiperidine dihydrochloride 1-Piperidinecarboxylicacid,3-amino-,1,1-dimethylethylester(9CI) 1-BOC-3-AMINOPIPERIDINE HYDROCHLORIDE 1-BOC-3-AMINOPIPERIDINE / 3-AMINO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 3-AMINO-1-BOC-PIPERIDINE X HCL, 3-AMINO-1-TERT-BUTOXYCARBONYL-PIPERIDINE X HCL >98% 3-Amino-1-tert-butoxycarbonylpiperidine > Linagliptin Impurity 102 Alogliptin Impurity 80 (+/-)-3-Amino-1-n-boc-piperidine citric acid salt ert-Butyl3-aminopiperidine-1-carboxylate tert-Butyl 3-Amino-1-piperidinecarboxylate N-BOC-3-Aminopiperidine USP/EP/BP 1-Piperidinecarboxylic acid, 3-amino-, 1,1-dimethylethyl ester (9CI, ACI) 3-amino-1-Piperidinecarboxylic acid 1,1-dimethylethyl ester (9CI ACI) N -B0C-3- Aminopiperidine CAS:184637-48-7 184637-48-7 C10H20N2O2xHCl C10H20N2O2C6H8O7 Piperidines Chiral Reagent