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TCS 46B

TCS 46B Structure
TCS 46B structure
CAS No.
302799-86-6
Chemical Name:
TCS 46B
Synonyms
TCS 46B;1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one;5-(3-(4-benzylpiperidin-1-yl)prop-1-yn-1-yl)-1H-benzo[d]imidazol-2(3H)-one;5-(3-(4-Benzylpiperidin-1-yl)prop-1-yn-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]-
CBNumber:
CB02453446
Molecular Formula:
C22H23N3O
Molecular Weight:
345.44
MDL Number:
MFCD09971137
MOL File:
302799-86-6.mol
MSDS File:
SDS
Last updated:2026-04-16 17:44:27
Product description Number Pack Size Price
TCS46b ≥98%(HPLC) 2782 10 $179
TCS46b ≥98%(HPLC) 2782 50 $662
TCS46b T012625 25mg $265
TCS 46b 466895 10mg $418
TCS 46b 256882 10mg $432
Request For Quotation

TCS 46B Properties

Boiling point 440.4±38.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Store at RT
solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
form Powder
pka 11.51±0.30(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

TCS 46B price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Tocris 2782 TCS46b ≥98%(HPLC) 302799-86-6 10 $179 2021-12-16 Buy
Tocris 2782 TCS46b ≥98%(HPLC) 302799-86-6 50 $662 2021-12-16 Buy
TRC T012625 TCS46b 302799-86-6 25mg $265 2021-12-16 Buy
Usbiological 466895 TCS 46b 302799-86-6 10mg $418 2021-12-16 Buy
Usbiological 256882 TCS 46b 302799-86-6 10mg $432 2021-12-16 Buy
Product number Packaging Price Buy
2782 10 $179 Buy
2782 50 $662 Buy
T012625 25mg $265 Buy
466895 10mg $418 Buy
256882 10mg $432 Buy

TCS 46B Chemical Properties,Uses,Production

Uses

TCS 46b is a subtype-selective NR1A/NR2B NMDA receptor antagonist.

Biological Activity

Orally active, subtype-selective NR1A/NR2B NMDA receptor antagonist (IC 50 values are 5.3, 35000 and > 100000 nM for NR1A/2B, NR1A/2A and NR1A/2C receptor subtypes respectively). Potentiates the effect of L-DOPA in 6-OHDA-lesioned rats following oral administration.

in vivo

TCS 46b (Compound 46b; 10 and 30 mg/kg; p.o. or i.p.; once) potentiates the effects of L-DOPA in the 6-OHDA-lesioned rat[1].

Animal Model:SpragueDawley rats, 6-hydroxydopamine-lesioned (6-OHDA) rat model[1]
Dosage:10 and 30 mg/kg
Administration:PO or IP, once
Result:Showed significant potentiation of the effects of L-DOPA in this model.

TCS 46B Preparation Products And Raw materials

Raw materials

Preparation Products

TCS 46B Suppliers

Global( 44)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32467 58
Chemtour Biotech Co., Ltd 		+8617327281506 market@chemtour.com China 1521 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69
Bide Pharmatech Ltd. 400-400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4817 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 86249 60
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Chemtour Biotech Co., Ltd 		58
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Bide Pharmatech Ltd. 60
Shanghai Lollane Biological Technology Co.,Ltd. 55
EMMX Biotechnology LLC 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
ShangHai Biochempartner Co.,Ltd 62

View Lastest Price from TCS 46B manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TCS 46b pictures 2026-04-16 TCS 46b
302799-86-6
 US $39.00-106.00 / mg 99.81% 10g TargetMol Chemicals Inc.
  • TCS 46b pictures
  • TCS 46b
    302799-86-6
  • US $39.00-106.00 / mg
  • 99.81%
  • TargetMol Chemicals Inc.

TCS 46B Spectrum

TCS 46B(302799-86-6)1HNMR

302799-86-6(TCS 46B)Related Search:

N-BUTYL-3-PHENYLPROP-2-YN-1-AMINE TCS 46B
TCS 46B 1,3-Dihydro-5-[3-[4-(phenylmethyl)-1-2H-benzimidazol-2-one 2H-Benzimidazol-2-one, 1,3-dihydro-5-[3-[4-(phenylmethyl)-1-piperidinyl]-1-propyn-1-yl]- 5-(3-(4-benzylpiperidin-1-yl)prop-1-yn-1-yl)-1H-benzo[d]imidazol-2(3H)-one 5-(3-(4-Benzylpiperidin-1-yl)prop-1-yn-1-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one 302799-86-6