L-N5-(1-Iminopropyl) ornithine (hydrochloride)
- CAS No.
- 150403-96-6
- Chemical Name:
- L-N5-(1-Iminopropyl) ornithine (hydrochloride)
- Synonyms
- Methyl-L-NIO Ηydrochloride;FADRJPGCWHNIBW-RGMNGODLSA-N;Methyl-L-NIO (hydrochloride);L-N5-(1-Iminopropyl) ornithine (hydrochloride)
- CBNumber:
- CB02454221
- Molecular Formula:
- C8H18ClN3O2
- Molecular Weight:
- 0
- MDL Number:
- MFCD10567090
- MOL File:
- 150403-96-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
L-N5-(1-Iminopropyl) ornithine (hydrochloride) price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10010252 | Methyl-L-NIO (hydrochloride) ≥98% | 150403-96-6 | 5mg | $71 | 2026-04-30 | Buy |
| Cayman Chemical | 10010252 | Methyl-L-NIO (hydrochloride) ≥98% | 150403-96-6 | 10mg | $131 | 2026-04-30 | Buy |
| Cayman Chemical | 10010252 | Methyl-L-NIO (hydrochloride) ≥98% | 150403-96-6 | 25mg | $308 | 2026-04-30 | Buy |
| Cayman Chemical | 10010252 | Methyl-L-NIO (hydrochloride) ≥98% | 150403-96-6 | 50mg | $547 | 2026-04-30 | Buy |
| ChemScene | CS-0179737 | Methyl-L-NIO hydrochloride | 150403-96-6 | 1mg | $61 | 2026-06-04 | Buy |
L-N5-(1-Iminopropyl) ornithine (hydrochloride) Chemical Properties,Uses,Production
Description
Nitric oxide synthase (NOS) catalyzes the conversion of L-
Uses
Methyl-L-NIO (compound 2d) hydrochloride is a potential selective inhibitor (IC50: 70 μM) of dimethylarginine dimethylaminohydrolase hDDAH. Methyl-L-NIO also has inhibitory activity against NO synthase. The inhibition rates of Methyl-L-NIO on different isoforms of NO synthase at a concentration of 100 μM are 77% (nNOS), 20% (eNOS), and 72% (iNOS) respectively; the inhibition rates at a concentration of 1 mM are 100% (nNOS), 85% (eNOS), 100% (iNOS)[1].
References
[1] Kotthaus J, et al. Structure–activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads[J]. Bioorganic & medicinal chemistry, 2008, 16(24): 10205-10209.
L-N5-(1-Iminopropyl) ornithine (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
L-N5-(1-Iminopropyl) ornithine (hydrochloride) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 29717 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
