Methyl 3-bromo-5-(bromomethyl)benzoate
- CAS No.
- 877624-40-3
- Chemical Name:
- Methyl 3-bromo-5-(bromomethyl)benzoate
- Synonyms
- Methyl 3-bromo-5-(bromomethyl)benzoate;3-Bromo-5-bromomethyl-benzoic acid methyl ester;Benzoic acid, 3-bromo-5-(bromomethyl)-, methyl ester
- CBNumber:
- CB02455576
- Molecular Formula:
- C9H8Br2O2
- Molecular Weight:
- 307.97
- MDL Number:
- MFCD11044991
- MOL File:
- 877624-40-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H302-H335-H318 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501 |
| HS Code | 2916399090 |
Methyl 3-bromo-5-(bromomethyl)benzoate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CKB62440 | Methyl 3-bromo-5-(bromomethyl)benzoate | 877624-40-3 | 2.5g | $324.5 | 2026-06-04 | Buy |
| Activate Scientific | AS42238 | Methyl 3-bromo-5-(bromomethyl)benzoate 98% | 877624-40-3 | 1g | $108 | 2026-06-04 | Buy |
| Activate Scientific | AS42238 | Methyl 3-bromo-5-(bromomethyl)benzoate 98% | 877624-40-3 | 5g | $316 | 2026-06-04 | Buy |
| Activate Scientific | AS42238 | Methyl 3-bromo-5-(bromomethyl)benzoate 98% | 877624-40-3 | 25g | $1026 | 2026-06-04 | Buy |
| Matrix Scientific | 102647 | Methyl 3-bromo-5-(bromomethyl)benzoate | 877624-40-3 | 1.00g | $67 | 2026-05-18 | Buy |
Methyl 3-bromo-5-(bromomethyl)benzoate Chemical Properties,Uses,Production
Synthesis
307353-32-8
877624-40-3
General procedure for the synthesis of methyl 3-bromo-5-(bromomethyl)benzoate from methyl 3-bromo-5-(hydroxymethyl)benzoate: methyl 3-bromo-5-(hydroxymethyl)benzoate (2.0 g, 8.2 mmol) was mixed with triphenylphosphine (4.28 g, 16.3 mmol) in tetrahydrofuran (20 mL) and the mixture was cooled down to 0°C. The reaction was completed by the addition of N-bromosuccinimidamide (3.05 g, 17.1 mmol). Subsequently, N-bromosuccinimide (3.05 g, 17.1 mmol) was added in batches and the reaction mixture was allowed to gradually warm up to room temperature. After 16 h of reaction, the reaction mixture was diluted with ethyl acetate, washed sequentially with saturated sodium bicarbonate solution (2×) and brine (2×), the organic phase was dried with anhydrous sodium sulfate and concentrated under reduced pressure. Purification by silica gel column chromatography (eluent: 10% ethyl acetate/hexane) gave 2.1 g of light brown oily product in 83% yield. The product was identified by 1H-NMR (CDCl3, 300 MHz): δ 8.07 (s, 1H), 7.96 (s, 1H), 7.70 (s, 1H), 4.42 (s, 2H), 3.90 (s, 3H). Mass spectrometry analysis showed a molecular ion peak of 308.93 (MH)+.
References
[1] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 85
Methyl 3-bromo-5-(bromomethyl)benzoate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9513 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| Shanghai Leto Pharmatech Co.,Ltd. | 86-021-5821 5861; 18016401466 | sales@letopharm.com | China | 235 | 58 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14982 | 55 |
| Shanghai Mayzem Pharmtech Co., Ltd. | 18501708306; 18501708306 | sales@mayzem.com | China | 518 | 56 |
| Changzhou Anxuan Chemical, Co., Ltd. | 13912302692 | sales@anxuanchem.com | China | 4824 | 58 |
| Shanghai PharmaPartner Co., Ltd. | 19983777532 | pharmabridge@163.com | China | 500 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Aikon International Limited | 025-66061636 19370895928 | qqyang@aikonchem.com | China | 15810 | 58 |
