CAY10397
- CAS No.
- 78028-01-0
- Chemical Name:
- CAY10397
- Synonyms
- CK47A;CAY10397;Ph CK 47A;CAY-10397,CAY10397;DPHOCQNZARWEHS-UHFFFAOYSA-N;5-[[4-(ETHOXYCARBONYL)PHENYL]AZO]-2-HYDROXY-BENZENEACETIC ACID;5-[2-[4-(Ethoxycarbonyl)phenyl]diazenyl]-2-hydroxybenzeneacetic acid;5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxybenzeneacetic acid, CK47A;Benzeneacetic acid, 5-[2-[4-(ethoxycarbonyl)phenyl]diazenyl]-2-hydroxy-
- CBNumber:
- CB0245681
- Molecular Formula:
- C17H16N2O5
- Molecular Weight:
- 328.32
- MDL Number:
- MFCD03412024
- MOL File:
- 78028-01-0.mol
CAY10397 price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C6734 | CAY10397 >98%, solid | 78028-01-0 | 1mg | $175 | 2025-07-31 | Buy |
| Cayman Chemical | 70130 | CAY10397 ≥98% | 78028-01-0 | 1mg | $59 | 2024-03-01 | Buy |
| Cayman Chemical | 70130 | CAY10397 ≥98% | 78028-01-0 | 5mg | $253 | 2024-03-01 | Buy |
| Cayman Chemical | 70130 | CAY10397 ≥98% | 78028-01-0 | 10mg | $448 | 2024-03-01 | Buy |
| Cayman Chemical | 70130 | CAY10397 ≥98% | 78028-01-0 | 25mg | $979 | 2024-03-01 | Buy |
CAY10397 Chemical Properties,Uses,Production
Uses
Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 μM. CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo.[Cayman Chemical]
Definition
ChEBI: CAY10397 is a member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 4 by an ethoxycarbonyl group, while the other is substituted by a carboxymethyl group at position 3 and a hydroxy group at position 4. It is a potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). It has a role as an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor. It is a dicarboxylic acid monoester, an ethyl ester, a member of azobenzenes and a member of phenols.
Biological Activity
Potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). Acts to prolong the lifetime and activity of endogenously produced prostaglandins both in vitro and in vivo.
CAY10397 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32431 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 12952 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4720 | 55 |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9923 | 65 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 4797 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24989 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
| Cayman Chemical Company | 800-364-9897 | sales@caymanchem.com | China | 6838 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Santa Cruz Biotechnology Inc | 021-60936350 | scbt@scbt.com | China | 6594 | 58 |
