2-Fluoro-5-hydroxybenzenecarbonitrile
- CAS No.
- 104798-53-0
- Chemical Name:
- 2-Fluoro-5-hydroxybenzenecarbonitrile
- Synonyms
- 2-Fluoro-5-hydroxybenzonitrile;3-Cyano-4-fluorophenol;2-Fluoro-5-hydroxybenzene;Fluoro-5-hydroxybenzonitrile;Benzonitrile, 2-fluoro-5-hydroxy-;2-Fluoro-5-hydroxybenzonitrile 98%;2-Fluoro-5-hydroxybenzenecarbonitrile
- CBNumber:
- CB02480914
- Molecular Formula:
- C7H4FNO
- Molecular Weight:
- 137.11
- MDL Number:
- MFCD11846514
- MOL File:
- 104798-53-0.mol
- MSDS File:
- SDS
| Melting point | 111-113° |
|---|---|
| Boiling point | 268℃ |
| Density | 1.34 |
| Flash point | 116℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| form | solid |
| pka | 8.59±0.18(Predicted) |
| color | White to off-white |
| InChI | InChI=1S/C7H4FNO/c8-7-2-1-6(10)3-5(7)4-9/h1-3,10H |
| InChIKey | HFLYBTRQFOKYHC-UHFFFAOYSA-N |
| SMILES | C(#N)C1=CC(O)=CC=C1F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311-H315-H319-H330-H335 |
| Precautionary statements | P280-P271-P260 |
| HazardClass | IRRITANT |
| HS Code | 2926907090 |
2-Fluoro-5-hydroxybenzenecarbonitrile price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC7202 | 2-Fluoro-5-hydroxybenzonitrile 98% | 104798-53-0 | 1g | $29 | 2026-06-04 | Buy |
| Apolloscientific | PC7202 | 2-Fluoro-5-hydroxybenzonitrile 98% | 104798-53-0 | 5g | $130 | 2026-06-04 | Buy |
| Activate Scientific | AS38759 | 2-Fluoro-5-hydroxybenzenecarbonitrile 97% | 104798-53-0 | 1g | $29 | 2026-06-04 | Buy |
| Activate Scientific | AS38759 | 2-Fluoro-5-hydroxybenzenecarbonitrile 97% | 104798-53-0 | 5g | $72 | 2026-06-04 | Buy |
| Activate Scientific | AS38759 | 2-Fluoro-5-hydroxybenzenecarbonitrile 97% | 104798-53-0 | 25g | $337 | 2026-06-04 | Buy |
2-Fluoro-5-hydroxybenzenecarbonitrile Chemical Properties, Uses, Production
Chemical Properties
off-white crytalline
Synthesis
127667-01-0
104798-53-0
Example 2 Steps for the synthesis of 2,4-diaminoquinazolin-6-yl-2,5-dimethoxybenzoate (Compound 32): Step I: 2-fluoro-5-methoxybenzonitrile (10 g, 0.066 mol) was dissolved in dry dichloromethane (DCM, 200 ml) and cooled to 0 °C. Boron tribromide (BBr3, 16 ml, 0.0092 mol) was slowly added under stirring, followed by warming the reaction mixture to room temperature and continuous stirring for 2 days. After completion of the reaction, the reaction was quenched with 10% sodium bicarbonate solution (50 ml). The aqueous layer was separated and extracted with dichloromethane (2 x 200 ml). The organic layers were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure to give the Step I product 2-fluoro-5-hydroxybenzonitrile (5.5 g, 61% yield). Thin layer chromatography (TLC) showed Rf = 0.4 (Expander: chloroform:methanol = 9:1).
References
[1] Patent: WO2008/152142, 2008, A1. Location in patent: Page/Page column 23
2-Fluoro-5-hydroxybenzenecarbonitrile Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai AQBioPharma Co., Ltd. | 13661411401 | yinglv.que@aqbiopharma.com.cn | China | 2976 | 58 |
| Shanghai AQ BioPharma Co., Ltd. | 13512160998; 13512160998 | sales@aqbiopharma.com.cn | China | 3007 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9388 | 66 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Sphchem Co., Ltd. | 021-56491756 13512199871 | 2819742715@qq.com | China | 3994 | 55 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Keepontech Co.,Ltd | 021-54849683 13601642561 | sales@keepontech.com | China | 991 | 59 |
View Latest Price from 2-Fluoro-5-hydroxybenzenecarbonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-10-20 | 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
|
100g | 97% | 500kg/M | Changsha YuTeng New Materials Co., Ltd. | ||
 |
2022-01-18 | 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
|
1KG | 97.2% | 100 tons | Honest Joy Holdings Limited | ||
 |
2019-07-06 | 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
|
$1.00 | 1kg | 98% | 1000kg | Career Henan Chemical Co |
-
- 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
- 97%
- Changsha YuTeng New Materials Co., Ltd.
-
- 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
- $0.00
- 97.2%
- Honest Joy Holdings Limited
-
- 2-Fluoro-5-hydroxybenzenecarbonitrile
104798-53-0
- $1.00
- 98%
- Career Henan Chemical Co
