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ChemicalBook >> CAS DataBase List >>2-FLUORO-5-METHOXYBENZONITRILE

2-FLUORO-5-METHOXYBENZONITRILE

2-FLUORO-5-METHOXYBENZONITRILE Structure
2-FLUORO-5-METHOXYBENZONITRILE structure
CAS No.
127667-01-0
Chemical Name:
2-FLUORO-5-METHOXYBENZONITRILE
Synonyms
BUTTPARK 80\01-21;3-Cyano-4-fluoroanisole;6-Fluoro-m-anisonitrile;Fluoromethoxybenzonitrile;Fluoromethoxybenzonitrile2;2-fluoro-methoxybenzonitrile;2-FLUORO-5-METHOXYBENZONITRILE;2-Fluoro-5-methyloxybenzonitrile;Benzonitrile, 2-fluoro-5-methoxy-;2-Fluoro-5-methoxybenzonitrile98%
CBNumber:
CB4293044
Molecular Formula:
C8H6FNO
Molecular Weight:
151.14
MDL Number:
MFCD00142921
MOL File:
127667-01-0.mol
MSDS File:
SDS
Last updated:2025-09-26 17:40:57
Product description Number Pack Size Price
2-Fluoro-5-methoxybenzonitrile Aldrich MNO000003 1g $42.8
2-Fluoro-5-methoxybenzonitrile >98.0%(GC) F0642 1g $28
2-Fluoro-5-methoxybenzonitrile >98.0%(GC) F0642 5g $109
2-Fluoro-5-methoxybenzonitrile F599393 50mg $45
2-Fluoro-5-methoxybenzonitrile F599393 100mg $60
More product size
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2-FLUORO-5-METHOXYBENZONITRILE Properties

Melting point 77-80°C
Boiling point 232.7±25.0 °C(Predicted)
Density 1.18±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
color White to Almost white
CAS DataBase Reference 127667-01-0(CAS DataBase Reference)
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331-H315-H335
Precautionary statements  P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes  T
Risk Statements  20/21/22-36/37/38-36/38
Safety Statements  26-36/37/39-45-36/37
RIDADR  3439
WGK Germany  3
Hazard Note  Toxic
HazardClass  6.1
PackingGroup  III
HS Code  29269090
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
3 0

2-FLUORO-5-METHOXYBENZONITRILE price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich MNO000003 2-Fluoro-5-methoxybenzonitrile Aldrich 127667-01-0 1g $42.8 2025-07-31 Buy
TCI Chemical F0642 2-Fluoro-5-methoxybenzonitrile >98.0%(GC) 127667-01-0 1g $28 2025-07-31 Buy
TCI Chemical F0642 2-Fluoro-5-methoxybenzonitrile >98.0%(GC) 127667-01-0 5g $109 2025-07-31 Buy
TRC F599393 2-Fluoro-5-methoxybenzonitrile 127667-01-0 50mg $45 2021-12-16 Buy
TRC F599393 2-Fluoro-5-methoxybenzonitrile 127667-01-0 100mg $60 2021-12-16 Buy
Product number Packaging Price Buy
MNO000003 1g $42.8 Buy
F0642 1g $28 Buy
F0642 5g $109 Buy
F599393 50mg $45 Buy
F599393 100mg $60 Buy

2-FLUORO-5-METHOXYBENZONITRILE Chemical Properties,Uses,Production

Synthesis

Benzaldehyde, 2-fluoro-5-methoxy-, oxime

796120-91-7

2-FLUORO-5-METHOXYBENZONITRILE

127667-01-0

The general procedure for the synthesis of 2-fluoro-5-methoxybenzonitrile from the compound (CAS: 796120-91-7) was as follows: 15 g of 2-fluoro-5-methoxybenzaldehyde oxime was dissolved in 150 mL of tetrahydrofuran, followed by the addition of 40 g of trifluoroacetic anhydride. 20 mL of triethylamine was slowly added under stirring. Upon completion of the reaction, the reaction mixture was concentrated to remove the solvent. Water was added to the concentrate and extracted with ethyl acetate. The organic phase was separated, dried with anhydrous sodium sulfate, and then concentrated to obtain the crude product. The crude product was purified by silica gel column chromatography to give 11 g of 2-fluoro-5-methoxybenzonitrile.

References

[1] Patent: CN107778264, 2018, A. Location in patent: Paragraph 0029; 0030
[2] Patent: CN107698535, 2018, A. Location in patent: Paragraph 0029; 0030
[3] Patent: CN108129415, 2018, A. Location in patent: Paragraph 0029-0030

2-FLUORO-5-METHOXYBENZONITRILE synthesis

796120-91-7
127667-01-0
Synthesis of 2-FLUORO-5-METHOXYBENZONITRILE from Benzaldehyde, 2-fluoro-5-methoxy-, oxime

2-FLUORO-5-METHOXYBENZONITRILE Preparation Products And Raw materials

Raw materials

Benzaldehyde, 2-fluoro-5-methoxy-, oxime 3-CHLORO-4-FLUOROANISOLE 2-FLUORO-5-METHOXYBENZALDEHYDE 5-Bromo-2-fluorobenzonitrile Methanol
4-Fluoroanisole Triethylamine Copper(I) Cyanide Trifluoroacetic anhydride Tetrahydrofuran

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Preparation Products

2-Fluoro-5-hydroxybenzenecarbonitrile 2-FLUORO-5-HYDROXYBENZOIC ACID

2-FLUORO-5-METHOXYBENZONITRILE Suppliers

Global( 208)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8768 58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		+8613343047651 admin@zlchemi.com China 3692 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29847 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Nanjing Dolon Biotechnology Co.,Ltd. 		18905173768 52513593@qq.com CHINA 2972 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Fuxin Pharmaceutical 		+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 10035 58
Supplier Advantage
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co.,Ltd 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Nanjing Dolon Biotechnology Co.,Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Fuxin Pharmaceutical 		58

View Lastest Price from 2-FLUORO-5-METHOXYBENZONITRILE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-FLUORO-5-METHOXYBENZONITRILE pictures 2025-11-27 2-FLUORO-5-METHOXYBENZONITRILE
127667-01-0
 US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
2-FLUORO-5-METHOXYBENZONITRILE pictures 2025-04-15 2-FLUORO-5-METHOXYBENZONITRILE
127667-01-0
 US $10.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
2-FLUORO-5-METHOXYBENZONITRILE pictures 2019-07-14 2-FLUORO-5-METHOXYBENZONITRILE
127667-01-0
 US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co

2-FLUORO-5-METHOXYBENZONITRILE Spectrum

2-FLUORO-5-METHOXYBENZONITRILE(127667-01-0)1HNMR

127667-01-0(2-FLUORO-5-METHOXYBENZONITRILE)Related Search:

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2-FLUORO-5-(TRIFLUOROMETHOXY)BENZONITRILE 4-Fluoroanisole Anisonitrile

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2-FLUORO-5-METHOXYBENZONITRILE BUTTPARK 80\01-21 Fluoromethoxybenzonitrile2 2-Fluoro-5-methyloxybenzonitrile 2-Fluoro-5-methoxybenzonitrile98% 6-Fluoro-m-anisonitrile 3-Cyano-4-fluoroanisole Benzonitrile, 2-fluoro-5-methoxy- 2-fluoro-methoxybenzonitrile 3-Cyano-4-fluoroanisole, 6-Fluoro-m-anisonitrile 2-Fluoro-5-methoxybenzonitrile> Fluoromethoxybenzonitrile 127667-01-0 Fluorine series Nitrile Anisoles, Alkyloxy Compounds & Phenylacetates Fluorine Compounds Nitriles Aromatic Nitriles