4-Bromo-2,6-dimethylaniline
- CAS No.
- 24596-19-8
- Chemical Name:
- 4-Bromo-2,6-dimethylaniline
- Synonyms
- 4-BROMO-2,6-XYLIDINE;2,6-Dimethyl-4-bromoaniline;6-diMethylaniline;TIMTEC-BB SBB002410;4-Bromo-2,6-dimethyl;2,6-Xylidine, 4-bromo-;LABOTEST-BB LT01143222;4-BROMO-2,6-DIMETHYLANILINE;4-broMo-2,6-deMethylaniline;6-dimethylaniline4-Bromo-2,
- CBNumber:
- CB0250184
- Molecular Formula:
- C8H10BrN
- Molecular Weight:
- 200.08
- MDL Number:
- MFCD00007826
- MOL File:
- 24596-19-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Bromo-2,6-dimethylaniline 98% | 192376 | 25g | $104 |
| 4-Bromo-2,6-dimethylaniline 98% | 192376 | 100g | $267 |
| 4-Bromo-2,6-dimethylaniline >98.0%(GC)(T) | B1909 | 25g | $66 |
| 4-Bromo-2,6-dimethylaniline >98.0%(GC)(T) | B1909 | 100g | $258 |
| 4-Bromo-2,6-xylidine | B689225 | 25g | $150 |
| More product size | |||
| Melting point | 48-51 °C (lit.) |
|---|---|
| Boiling point | 120°C 0,2mm |
| Density | 1.4423 (rough estimate) |
| refractive index | 1.5748 (estimate) |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform, Methanol |
| pka | 3.60±0.10(Predicted) |
| form | Liquid |
| color | Clear yellow to orange to amber |
| BRN | 1936300 |
| InChI | InChI=1S/C8H10BrN/c1-5-3-7(9)4-6(2)8(5)10/h3-4H,10H2,1-2H3 |
| InChIKey | QGLAYJCJLHNIGJ-UHFFFAOYSA-N |
| SMILES | C1(N)=C(C)C=C(Br)C=C1C |
| CAS DataBase Reference | 24596-19-8(CAS DataBase Reference) |
| FDA UNII | 9W5K8J5F6B |
| NIST Chemistry Reference | Benzenamine, 4-bromo-2,6-dimethyl-(24596-19-8) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS06,GHS08,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H311+H331-H315-H335-H351-H410 | |||||||||
| Precautionary statements | P273-P280-P301+P312-P302+P352+P312-P304+P340+P311-P308+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 38-43-36/37/38-20/21/22 | |||||||||
| Safety Statements | 36/37-36/37/39-26 | |||||||||
| RIDADR | UN2811/6.1/III | |||||||||
| WGK Germany | 3 | |||||||||
| F | 8-10-23 | |||||||||
| Hazard Note | Harmful | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29214990 | |||||||||
| NFPA 704 |
|
4-Bromo-2,6-dimethylaniline price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 192376 | 4-Bromo-2,6-dimethylaniline 98% | 24596-19-8 | 25g | $104 | 2025-07-31 | Buy |
| Sigma-Aldrich | 192376 | 4-Bromo-2,6-dimethylaniline 98% | 24596-19-8 | 100g | $267 | 2025-07-31 | Buy |
| TCI Chemical | B1909 | 4-Bromo-2,6-dimethylaniline >98.0%(GC)(T) | 24596-19-8 | 25g | $66 | 2025-07-31 | Buy |
| TCI Chemical | B1909 | 4-Bromo-2,6-dimethylaniline >98.0%(GC)(T) | 24596-19-8 | 100g | $258 | 2025-07-31 | Buy |
| TRC | B689225 | 4-Bromo-2,6-xylidine | 24596-19-8 | 25g | $150 | 2021-12-16 | Buy |
4-Bromo-2,6-dimethylaniline Chemical Properties,Uses,Production
Chemical Properties
brown crystals
Uses
4-Bromo-2,6-dimethylaniline has been used in the preparation of:
- 4-bromo-N-(1-(6-(1-isopropyl-1H-benzo[d]imidazol-2-yl)pyridin-2-yl)ethylidene)-2,6-dimethylbenzenamine
- N-(4-Bromo-2,6-dimethylphenyl)-5-trimethylammoniumsalicylaldimine chloride
- ethynyl-functionalized persistent perylene diimide-multichromophore
Reactions
4-Bromo-2,6-dimethylaniline has been shown to react with acid solutions to form hydrogen bromide gas and ammonium chloride crystals.
Synthesis
87-62-7
24596-19-8
The general procedure for the synthesis of 4-bromo-2,6-dimethylaniline from 2,6-dimethylaniline was as follows: 1-methoxy-3,5-dimethylbenzene (100 mg, 0.73 mmol), N-bromosuccinimide (NBS, 260 mg, 1.46 mmol), and a stainless steel ball (5 mm in diameter) were placed in a 10 mL stainless steel grinding jar. The ball milling reaction was carried out and the reaction process was monitored by thin layer chromatography (TLC) and proton nuclear magnetic resonance (1H NMR). Upon completion of the reaction, the reaction mixture was transferred to 30 mL of ethyl acetate and cooled at 0°C. The filtrate (containing product) and precipitate (spent succinimide) were obtained by filtration through filter paper and separated. The filtrate was concentrated under vacuum to give 250 mg (85% yield) of 4-bromo-2,6-dimethylaniline (2b) as a colorless powder. To test the efficiency of the large-scale reaction, monobromination was carried out under the same conditions using 1.3 g of 1-methoxy-3,5-dimethylbenzene for 1 h. The product was isolated in 87% yield. During the reaction, the grinding equipment was suspended and a small amount of sample was removed from the reaction tank for TLC and 1H NMR analysis, after which the reaction was continued, and the time of this operation was not included in the total reaction time.
References
[1] Tetrahedron Letters, 2005, vol. 46, # 51, p. 8959 - 8963
[2] Tetrahedron Letters, 2009, vol. 50, # 9, p. 1007 - 1009
[3] Synthetic Communications, 2010, vol. 40, # 5, p. 647 - 653
[4] Synthetic Communications, 2009, vol. 39, # 23, p. 4212 - 4220
[5] Journal fuer Praktische Chemie (Leipzig), 1988, vol. 330, # 2, p. 161 - 174
4-Bromo-2,6-dimethylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +1-5184799099 | lbaochemicals@gmail.com | China | 317 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8772 | 58 |
| Sichuan Zhuoyu Yantang Technology Co., Ltd. | +8613288715578 | sales@sichuanzyyt.com | China | 12247 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20175 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | stella@zetchem.com | China | 2161 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
View Lastest Price from 4-Bromo-2,6-dimethylaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-10-16 | 4-bromo-2,6-dimethylaniline
24596-19-8
|
US $0.00-0.00 / kg | 25kg | 98% | Customise | Hefei Lbao Physical & Chemical Science Co.,Ltd | |
 |
2025-10-11 | 4-Bromo-2,6-dimethylaniline
24596-19-8
|
US $10.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-09-25 | 4-bromo-2,6-xylidine
24596-19-8
|
US $50.00-1.00 / KG | 1KG | 99 | g-kg-tons,free sample is available | Henan Fengda Chemical Co., Ltd |
-
- 4-bromo-2,6-dimethylaniline
24596-19-8
- US $0.00-0.00 / kg
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 4-Bromo-2,6-dimethylaniline
24596-19-8
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-bromo-2,6-xylidine
24596-19-8
- US $50.00-1.00 / KG
- 99
- Henan Fengda Chemical Co., Ltd
