4-Bromo-3-fluorobenzaldehyde
- CAS No.
- 133059-43-5
- Chemical Name:
- 4-Bromo-3-fluorobenzaldehyde
- Synonyms
- CAS:133059-43-5;3-Fluoro-4-bromobenzaldehyde;4-BROMO-3-FLUOROBENZALDEHYDE;Benzaldehyde, 4-broMo-3-fluoro-;4-Bromo-3-fluorobenzaldehyde98%;4-Bromo-3-fluorobenzaldehyde 98%;4-Bromo-3-fluorobenzaldehyde >4-BroMo-3-fluorobenzaldehyde, 95+%;4 - broMine - 3 - fluoro benzaldehyde;4-Bromo-3-fluorobenzaldehyde ISO 9001：2015 REACH
- CBNumber:
- CB2459765
- Molecular Formula:
- C7H4BrFO
- Molecular Weight:
- 203.01
- MDL Number:
- MFCD03095000
- MOL File:
- 133059-43-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 55-59 °C |
|---|---|
| Boiling point | 240.2±25.0 °C(Predicted) |
| Density | 1.670±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| color | White to Light yellow |
| InChI | InChI=1S/C7H4BrFO/c8-6-2-1-5(4-10)3-7(6)9/h1-4H |
| InChIKey | SWHUROFMIMHWKS-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(Br)C(F)=C1 |
| CAS DataBase Reference | 133059-43-5(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H319 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P305+P351+P338-P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-36-22 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 29130000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 |
|||||||||
| REACH Registrations | Inactive | |||||||||
| NFPA 704 |
|
4-Bromo-3-fluorobenzaldehyde price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 706310 | 4-Bromo-3-fluorobenzaldehyde 97% | 133059-43-5 | 1g | $81.5 | 2023-06-20 | Buy |
| TCI Chemical | B4319 | 4-Bromo-3-fluorobenzaldehyde >98.0%(GC) | 133059-43-5 | 5g | $74 | 2026-04-30 | Buy |
| TCI Chemical | B4319 | 4-Bromo-3-fluorobenzaldehyde >98.0%(GC) | 133059-43-5 | 25g | $256 | 2026-04-30 | Buy |
| Usbiological | 267271 | 4-Bromo-3-fluorobenzaldehyde Asreported | 133059-43-5 | 10g | $362 | 2026-06-03 | Buy |
| Usbiological | 267271 | 4-Bromo-3-fluorobenzaldehyde Asreported | 133059-43-5 | 25g | $521 | 2026-06-03 | Buy |
4-Bromo-3-fluorobenzaldehyde Chemical Properties, Uses, Production
Chemical Properties
White powder
Uses
4-Bromo-3-fluorobenzaldehyde is used in preparation of the Deuterated Dihydropyrimidine compound and their application as anti-HBV agent.
Synthesis
222978-01-0
133059-43-5
General procedure for the synthesis of 3-fluoro-4-bromobenzaldehyde from 4-bromo-3-fluorobenzyl alcohol: Manganese dioxide (18.7 g, 210 mmol) was added to a solution of 4-bromo-3-fluorobenzyl alcohol (4.3 g, 21 mmol) in chloroform (50 mL), and the reaction mixture was stirred at 37 °C overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) until the raw material was completely consumed. Upon completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure to afford the target product 3-fluoro-4-bromobenzaldehyde (2.3 g, 55% yield).
References
[1] Patent: US2010/216806, 2010, A1. Location in patent: Page/Page column 103
[2] Patent: US6297239, 2001, B1
4-Bromo-3-fluorobenzaldehyde Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
View Latest Price from 4-Bromo-3-fluorobenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-03-20 | 4-Bromo-3-fluorobenzaldehyde
133059-43-5
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2019-07-06 | 4-Bromo-3-fluorobenzaldehyde
133059-43-5
|
$1.00 | 1KG | 99% | Career Henan Chemical Co |
-
- 4-Bromo-3-fluorobenzaldehyde
133059-43-5
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 4-Bromo-3-fluorobenzaldehyde
133059-43-5
- $1.00
- 99%
- Career Henan Chemical Co
