METHYL 5-BROMO-2-IODOBENZOATE
- CAS No.
- 181765-86-6
- Chemical Name:
- METHYL 5-BROMO-2-IODOBENZOATE
- Synonyms
- 5-Bromo-2-iodobenzoate;5-Bromo-2-iodo-benzoic acid methyl ester;QCF4;Methyl 2-Iodo-5-Bromobenzoate;5-bromo-2-iodobenzoate methyl;Benzoic acid,5-broMo-2-iodo-, Methyl ester;Methyl 5-
broMo- 2- iodobenzoate;METHYL 5-BROMMETHYL 5-BROMO-2-IODOBENZOATEO-2-IODOBENZOATE
- CBNumber:
- CB2972909
- Molecular Formula:
- C8H6BrIO2
- Molecular Weight:
- 340.94
- MDL Number:
- MFCD00144771
- MOL File:
- 181765-86-6.mol
| Product description | Number | Pack Size | Price |
| Methyl 5-bromo-2-iodobenzoate 97% | 652601 | 10g | $165 |
| Methyl 5-Bromo-2-iodobenzoate >95.0%(GC) | M3084 | 1g | $17 |
| Methyl 5-Bromo-2-iodobenzoate >95.0%(GC) | M3084 | 5g | $63 |
| Methyl 5-bromo-2-iodobenzoate | M220575 | 1g | $75 |
| Methyl 5-bromo-2-iodobenzoate 98% | 083254 | 5g | $78 |
| More product size | |||
| Melting point | 45-49 °C (lit.) |
|---|---|
| Boiling point | 134°C/1mmHg(lit.) |
| Density | 2.059±0.06 g/cm3(Predicted) |
| Flash point | 113℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| color | White to Orange to Green |
| InChIKey | CJRHLSZJEFJDLA-UHFFFAOYSA-N |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
METHYL 5-BROMO-2-IODOBENZOATE price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 652601 | Methyl 5-bromo-2-iodobenzoate 97% | 181765-86-6 | 10g | $165 | 2025-07-31 | Buy |
| TCI Chemical | M3084 | Methyl 5-Bromo-2-iodobenzoate >95.0%(GC) | 181765-86-6 | 1g | $17 | 2025-07-31 | Buy |
| TCI Chemical | M3084 | Methyl 5-Bromo-2-iodobenzoate >95.0%(GC) | 181765-86-6 | 5g | $63 | 2025-07-31 | Buy |
| TRC | M220575 | Methyl 5-bromo-2-iodobenzoate | 181765-86-6 | 1g | $75 | 2021-12-16 | Buy |
| Matrix Scientific | 083254 | Methyl 5-bromo-2-iodobenzoate 98% | 181765-86-6 | 5g | $78 | 2021-12-16 | Buy |
METHYL 5-BROMO-2-IODOBENZOATE Chemical Properties,Uses,Production
Chemical Properties
off-white powder
Synthesis
610-97-9
181765-86-6
Concentrated sulfuric acid (10 mL) was added dropwise to a stirred solution of methyl 2-iodobenzoate (5.0 g, 19.08 mmol, 1.0 eq.) and N-bromosuccinimide (NBS, 3.73 g, 20.99 mmol, 1.1 eq.) in acetic acid (10 mL), keeping the reaction temperature between 20-40 °C. The reaction mixture was stirred at room temperature for 88 hours and then warmed up to 50°C and continued stirring for 4 hours. Upon completion of the reaction, the mixture was cooled to 10 °C and the reaction was quenched with cold water (40 mL) and subsequently extracted with dichloromethane (DCM, 3 x 50 mL). The organic layers were combined and washed sequentially with 5% sodium bicarbonate solution (2 × 50 mL), 10% sodium sulfite solution (50 mL), and water (50 mL), then dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give the crude product methyl 5-bromo-2-iodobenzoate. The crude product was purified by rapid column chromatography on silica gel, the eluent being a hexane solution of 10% ethyl acetate. The pure grade was collected and the solvent was evaporated under reduced pressure to give methyl 5-bromo-2-iodobenzoate as an off-white solid (5 g, 77% yield). NMR hydrogen spectrum (400 MHz, CDCl3) δppm: 3.94 (s, 3H), 7.26-7.29 (m, 1H), 7.83 (d, J=8.4 Hz, 1H), 7.93 (d, J=8.8 Hz, 1H).
References
[1] Patent: WO2018/15879, 2018, A1. Location in patent: Page/Page column 81
[2] Patent: US2004/92521, 2004, A1. Location in patent: Page/Page column 16-20; 46
[3] Patent: US2005/256118, 2005, A1. Location in patent: Page/Page column 18-19
[4] Patent: US2005/256309, 2005, A1. Location in patent: Page/Page column 20-21; 36
[5] Patent: US2005/272728, 2005, A1. Location in patent: Page/Page column 19-20
METHYL 5-BROMO-2-IODOBENZOATE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29734 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13456 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| BAYNOE CHEM CO.,LTD | +86-21-34783353 +8615000719740 | baynoe@baynoe.com | CHINA | 934 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
View Lastest Price from METHYL 5-BROMO-2-IODOBENZOATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-08-25 | methyl 5-bromo-2-iodobenzoate
181765-86-6
|
US $0.00 / kg | 20kg | 99% | 20 tons | Qingdao RENAS Polymer Material Co., Ltd. | |
 |
2024-06-11 | METHYL 5-BROMO-2-IODOBENZOATE
181765-86-6
|
US $0.00-0.00 / G | 10G | 0.98 | 500kg | Kindchem(Nanjing)Co.,Ltd | |
 |
2020-01-01 | METHYL 5-BROMO-2-IODOBENZOATE
181765-86-6
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- methyl 5-bromo-2-iodobenzoate
181765-86-6
- US $0.00 / kg
- 99%
- Qingdao RENAS Polymer Material Co., Ltd.
-
- METHYL 5-BROMO-2-IODOBENZOATE
181765-86-6
- US $0.00-0.00 / G
- 0.98
- Kindchem(Nanjing)Co.,Ltd
-
- METHYL 5-BROMO-2-IODOBENZOATE
181765-86-6
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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