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N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE structure

CAS No.: 5472-49-1

Chemical Name:: N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE

Synonyms: PIPERIDINOPROPYL CHLORIDE HCL;N-(3-CHLOROPROPYL)PIPERIDINE HCL;1-(3-CHLOROPROPYL)PIPERIDINE HCL 98%;piperidinopropylchloride,hydrochloride;1-(3-CHLOROPROPYL) PIPERIDINE HYDROCHLO&;1-(3-chloropropyl)-piperidinhydrochloride;3-Piperidinopropyl Chloride Hydrochloride;N-(3-CHLOROPROPYL)PIPERIDINE?HYDROCHLORID;1-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE;N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE

CBNumber:: CB0258362

Molecular Formula:: C8H17Cl2N

Molecular Weight:: 198.13

MDL Number:: MFCD00012838

MOL File:: 5472-49-1.mol

MSDS File:: SDS

Last updated:2026-01-13 11:13:02

Product description	Number	Pack Size	Price
1-(3-Chloropropyl)piperidine monohydrochloride 97%	596310	10g	$166
1-(3-Chloropropyl)piperidine Hydrochloride >98.0%(T)	C2922	1g	$36
1-(3-Chloropropyl)piperidine Hydrochloride >98.0%(T)	C2922	5g	$130
1-(3-Chloropropyl)piperidine Hydrochloride	C429300	2.5g	$60
1-(3-Chloropropyl)piperidine Hydrochloride 98%	JK305007	5g	$84
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N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE Properties

Melting point	219-223 °C(lit.)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility	Soluble in water
form	Powder or Crystalline Powder
color	White to yellow
InChI	InChI=1S/C8H16ClN.ClH/c9-5-4-8-10-6-2-1-3-7-10;/h1-8H2;1H
InChIKey	OBOBUDMMFXRNDO-UHFFFAOYSA-N
SMILES	N1(CCCCl)CCCCC1.Cl
CAS DataBase Reference	5472-49-1
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36

WGK Germany

RTECS

TM6498600

HS Code

29333990

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	0
1		0

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	596310	1-(3-Chloropropyl)piperidine monohydrochloride 97%	5472-49-1	10g	$166	2023-06-20	Buy
TCI Chemical	C2922	1-(3-Chloropropyl)piperidine Hydrochloride >98.0%(T)	5472-49-1	1g	$36	2025-07-31	Buy
TCI Chemical	C2922	1-(3-Chloropropyl)piperidine Hydrochloride >98.0%(T)	5472-49-1	5g	$130	2025-07-31	Buy
TRC	C429300	1-(3-Chloropropyl)piperidine Hydrochloride	5472-49-1	2.5g	$60	2021-12-16	Buy
Frontier Specialty Chemicals	JK305007	1-(3-Chloropropyl)piperidine Hydrochloride 98%	5472-49-1	5g	$84	2021-12-16	Buy

Product number	Packaging	Price	Buy
596310	10g	$166	Buy
C2922	1g	$36	Buy
C2922	5g	$130	Buy
C429300	2.5g	$60	Buy
JK305007	5g	$84	Buy

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

1-(3-Chloropropyl)piperidine Hydrochloride is used in preparation of Triazolotriazine derivatives as A2A receptor antagonists.

Synthesis

110-89-4

109-70-6

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE

5472-49-1

Hexahydropyridine (piperidine, 0.45 g, 5.3 mmol) and 1-bromo-3-chloropropane (5.2 g, 33 mmol) were dissolved in toluene (17.5 mL) and then tetra-n-ammonium hydrogensulfate (ammonium hydrogensulfate, 0.51 g, 1.5 mmol) and 25% aqueous sodium hydroxide solution (10 mL) were added. The reaction mixture was stirred at 40 °C for 3 hours. After completion of the reaction, the mixture was cooled to room temperature, the toluene layer was separated, washed with saturated aqueous sodium chloride solution and dried over anhydrous sodium sulfate. After removal of sodium sulfate by filtration, hydrochloric acid/methanol solution (2 mL) was added to the filtrate and the mixture was subsequently concentrated. The resulting crude product was purified by recrystallization from methanol/ether to give N-(3-chloropropyl)piperidine hydrochloride (0.96 g, 91% yield) as white crystals.

References

[1] Patent: US6642228, 2003, B1. Location in patent: Page/Page column 76-77

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Piperidine 1-Bromo-3-chloropropane 3-Chloro-1-propanol Hydrochloric acid Tetrabutylammonium hydrogen sulfate

Methanol Toluene Sodium hydroxide

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Preparation Products

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE Suppliers

Global( 124)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou uniringchem Co., Ltd.	+undefined13585446801	sales@uniringchem.com	China	69	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29831	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 +86-17392581500	1015@dideu.com	China	3986	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Jinjiangchem Corporation	512-50133713	sales@jinjiangchem.com	CHINA	1072	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52746	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9653	58
GIHI CHEMICALS CO.,LIMITED	+86-571-86217390; +8618058761490	info@gihichemicals.com	China	49964	58

Supplier	Advantage
Changzhou uniringchem Co., Ltd.	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Jinjiangchem Corporation	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
changzhou huayang technology co., ltd	58
GIHI CHEMICALS CO.,LIMITED	58

View Lastest Price from N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-08-02	N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE 5472-49-1	US $1.00 / KG	1KG	95-99%	500kg/month	Career Henan Chemical Co

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE
5472-49-1
US $1.00 / KG
95-99%
Career Henan Chemical Co

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE Spectrum

N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)MS N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)¹HNMR N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)¹³CNMR N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)IR1 N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)IR2 N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE(5472-49-1)Raman

5472-49-1(N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE)Related Search:

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3-Chloro-1-(N,N-dimethyl)propylamine 3-DIETHYLAMINOPROPYL CHLORIDE ETHYL 1-(3-CHLOROPROPYL)-4-PHENYLPIPERIDINE-4-CARBOXYLATE HYDROCHLORIDE 3-DIETHYLAMINOPROPYL CHLORIDE HYDROCHLORIDE 1-(3-Chloropropyl)piperidine HCl

N-METHYL-3-CHLOROPROPYLAMINE HYDROCHLORIDE

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N-(3-CHLOROPROPYL)PIPERIDINE HCL N-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE PIPERIDINOPROPYL CHLORIDE HCL 1-(3-CHLOROPROPYL)PIPERIDINE HYDROCHLORIDE 1-(3-chloropropyl)-piperidinhydrochloride piperidinopropylchloride,hydrochloride N-(3-Chloropropyl)piperidine hydrochloride,97% 1-(3-CHLOROPROPYL) PIPERIDINE HYDROCHLO& 1-(3-chloropropyl)piperidine monohydrochloride 1-(3-CHLOROPROPYL)PIPERIDINE HCL 98% 1-(3-Chloropropyl)piperidine monohydrochloride 97% 1-(3-Chloropropyl)piperidine Hydrochloride > Piperidine,1-(3-chloropropyl)-,hydrochloride(1:1) 3-Piperidinopropyl Chloride Hydrochloride 1-(3-Chloropropyl)piperidine hydrochloride (1:1) N-(3-CHLOROPROPYL)PIPERIDINE?HYDROCHLORID 5472-49-1 Piperidines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Building Blocks C5 to C9 C8 Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks Piperidines PiperidinesHeterocyclic Building Blocks