1-Boc-5-hydroxyindole
- CAS No.
- 434958-85-7
- Chemical Name:
- 1-Boc-5-hydroxyindole
- Synonyms
- 1-Boc-1H-indol-5-ol;5-AMINOPHTHALIC ACID;1-BOC-5-HYDROXYINDOLE;N-BOC-5-HYDROXYINDOLE;5-hydroxy-1-indolecarboxylate;5-hydroxy-1H-indole-1-carboxylate;tert-butyl 5-hydroxyindole-1-carboxylate;tert-butyl 5-hydroxy-1H-indole-1-carboxylate;1H-Indole-1-carboxylic acid, 5-hydroxy-,1,1-diMethylethyl ester
- CBNumber:
- CB0275347
- Molecular Formula:
- C13H15NO3
- Molecular Weight:
- 233.26
- MDL Number:
- MFCD08272246
- MOL File:
- 434958-85-7.mol
- MSDS File:
- SDS
| Boiling point | 374.5±34.0 °C(Predicted) |
|---|---|
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 9.55±0.40(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 434958-85-7(CAS DataBase Reference) |
1-Boc-5-hydroxyindole price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR305227 | tert-Butyl 5-hydroxy-1H-indole-1-carboxylate 95% | 434958-85-7 | 250mg | $66 | 2026-06-04 | Buy |
| Apolloscientific | OR305227 | tert-Butyl 5-hydroxy-1H-indole-1-carboxylate 95% | 434958-85-7 | 1g | $96 | 2026-06-04 | Buy |
| Synthonix | B56917 | N-Boc-5-Hydroxyindole 95+% | 434958-85-7 | 100mg | $35 | 2026-05-06 | Buy |
| Synthonix | B56917 | N-Boc-5-Hydroxyindole 95+% | 434958-85-7 | 250mg | $39 | 2026-05-06 | Buy |
| Synthonix | B56917 | N-Boc-5-Hydroxyindole 95+% | 434958-85-7 | 1g | $41 | 2026-05-06 | Buy |
1-Boc-5-hydroxyindole Chemical Properties, Uses, Production
Synthesis
170147-29-2
434958-85-7
General procedure for the synthesis of N-Boc-5-hydroxyindole from tert-butyl 5-(benzyloxy)-1H-indole-1-carboxylate: the product of Example 93A (680 mg, 2.103 mmol) was dissolved in ethanol (20 mL) under nitrogen protection, and 10% palladium carbon (68 mg) and ammonium formate (265 mg, 4.205 mmol) were added. After stirring the reaction for 1 h at room temperature, the reaction mixture was filtered through a 0.45 μm PTFE membrane and the catalyst was washed with methanol. The filtrate was concentrated by rotary evaporator and the resulting residue was dissolved in ethyl acetate (50 mL) and washed sequentially with water (2 × 25 mL) and saturated saline (25 mL). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give N-Boc-5-hydroxyindole (475 mg, 96% yield) as a white solid.
References
[1] Patent: WO2007/76034, 2007, A2. Location in patent: Page/Page column 127
[2] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 57
1-Boc-5-hydroxyindole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing XiZe Biotechnology CO., Ltd. | 025-66023220 15250997978 | 1511893459@qq.com | China | 4777 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
| Sphinx Scientific Laboratory (Tianjin) Co., Ltd. | 022-66211289-843 13672102692 | contact@sphinxpharm.com | China | 361 | 62 |
| ZhengZhou HuaWen Chemical Co.Ltd | 0370-2785118 17550508557 | 675141927@qq.com | China | 3201 | 55 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
View Latest Price from 1-Boc-5-hydroxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | 1-Boc-5-hydroxyindole
434958-85-7
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-07-06 | 1-Boc-5-hydroxyindole
434958-85-7
|
$1.00 | 1KG | 95% | 500kg | Career Henan Chemical Co |
-
- 1-Boc-5-hydroxyindole
434958-85-7
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-Boc-5-hydroxyindole
434958-85-7
- $1.00
- 95%
- Career Henan Chemical Co
