1-Boc-5-hydroxyindole
- CAS No.
- 434958-85-7
- Chemical Name:
- 1-Boc-5-hydroxyindole
- Synonyms
- 1-Boc-1H-indol-5-ol;5-AMINOPHTHALIC ACID;1-BOC-5-HYDROXYINDOLE;N-BOC-5-HYDROXYINDOLE;5-hydroxy-1-indolecarboxylate;5-hydroxy-1H-indole-1-carboxylate;tert-butyl 5-hydroxyindole-1-carboxylate;tert-butyl 5-hydroxy-1H-indole-1-carboxylate;1H-Indole-1-carboxylic acid, 5-hydroxy-,1,1-diMethylethyl ester
- CBNumber:
- CB0275347
- Molecular Formula:
- C13H15NO3
- Molecular Weight:
- 233.26
- MDL Number:
- MFCD08272246
- MOL File:
- 434958-85-7.mol
- MSDS File:
- SDS
| Boiling point | 374.5±34.0 °C(Predicted) |
|---|---|
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 9.55±0.40(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 434958-85-7(CAS DataBase Reference) |
1-Boc-5-hydroxyindole price More Price(26)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B656693 | N-Boc-5-Hydroxyindole | 434958-85-7 | 500mg | $130 | 2021-12-16 | Buy |
| Matrix Scientific | 072860 | N-Boc-5-Hydroxyindole 95+% | 434958-85-7 | 1g | $163 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140244 | tert-Butyl 5-hydroxy-1H-indole-1-carboxylate | 434958-85-7 | 5G | $363 | 2021-12-16 | Buy |
| AK Scientific | W6280 | N-Boc-5-Hydroxyindole | 434958-85-7 | 10g | $537 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140244 | tert-Butyl 5-hydroxy-1H-indole-1-carboxylate | 434958-85-7 | 10g | $631.3 | 2021-12-16 | Buy |
1-Boc-5-hydroxyindole Chemical Properties,Uses,Production
Synthesis
170147-29-2
434958-85-7
General procedure for the synthesis of N-Boc-5-hydroxyindole from tert-butyl 5-(benzyloxy)-1H-indole-1-carboxylate: the product of Example 93A (680 mg, 2.103 mmol) was dissolved in ethanol (20 mL) under nitrogen protection, and 10% palladium carbon (68 mg) and ammonium formate (265 mg, 4.205 mmol) were added. After stirring the reaction for 1 h at room temperature, the reaction mixture was filtered through a 0.45 μm PTFE membrane and the catalyst was washed with methanol. The filtrate was concentrated by rotary evaporator and the resulting residue was dissolved in ethyl acetate (50 mL) and washed sequentially with water (2 × 25 mL) and saturated saline (25 mL). The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum to give N-Boc-5-hydroxyindole (475 mg, 96% yield) as a white solid.
References
[1] Patent: WO2007/76034, 2007, A2. Location in patent: Page/Page column 127
[2] Patent: WO2005/51957, 2005, A1. Location in patent: Page/Page column 57
1-Boc-5-hydroxyindole Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29852 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8826 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49977 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8467 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +8613523716970 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
View Lastest Price from 1-Boc-5-hydroxyindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-08-12 | 1-Boc-5-hydroxyindole
434958-85-7
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | 1-Boc-5-hydroxyindole
434958-85-7
|
US $1.00 / KG | 1KG | 95% | 500kg | Career Henan Chemical Co |
-
- 1-Boc-5-hydroxyindole
434958-85-7
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 1-Boc-5-hydroxyindole
434958-85-7
- US $1.00 / KG
- 95%
- Career Henan Chemical Co
