DIFETHIALONE
- CAS No.
- 104653-34-1
- Chemical Name:
- DIFETHIALONE
- Synonyms
- LM2219;Baraki;RODILON;Hsdb 7119;GENERATION;Difethiarol;ifethialone;DIFETHIALONE;Difethialone-13C6;Difethialone [iso]
- CBNumber:
- CB0304070
- Molecular Formula:
- C31H23BrO2S
- Molecular Weight:
- 539.48
- MDL Number:
- MFCD01663605
- MOL File:
- 104653-34-1.mol
- MSDS File:
- SDS
| Melting point | 203-227° |
|---|---|
| Boiling point | 658.3±55.0 °C(Predicted) |
| Density | 1.3614 g/cm3(Temp: 25 °C) |
| solubility | Chloroform: slightly soluble; Methanol: slightly soluble |
| form | A solid |
| pka | 4.50±1.00(Predicted) |
| Henry's Law Constant | 9.9×100 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| FDA UNII | KOL4VXI5O0 |
| Pesticides Freedom of Information Act (FOIA) | Difethialone |
| EPA Substance Registry System | Difethialone (104653-34-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS08,GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300-H310-H330-H360D-H372-H410 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501-P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P260-P264-P270-P314-P501-P273-P391-P501 | |||||||||
| RIDADR | UN2588 (Pesticide, solid, poi- sonous, n.o.s.); UN2902 (Pesticide, liquid, poisonous, n.o.s.) | |||||||||
| HS Code | 29349990 | |||||||||
| Hazardous Substances Data | 104653-34-1(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 orally in male, female rats, mice (mg/kg): 0.62, 0.42, 0.52, 0.43 (non-resistant); 0.27, 0.39, 0.46, 0.52 (warfarin resistant); LD50 in hare: 0.75 mg/kg; LC50 in mallard duck, bobwhite quail (ppm): 1.94, 0.56; LD50 at 48 hrs in daphnia magna, bluegill sunfish, rainbow trout (mg/l): 4.4, 110, 67 (Lechevin) | |||||||||
| NFPA 704 |
|
DIFETHIALONE price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 36225 | Difethialone ≥98% | 104653-34-1 | 1mg | $439 | 2026-04-30 | Buy |
| TRC | TRC-D445450-1MG | Difethialone >95%(HPLC) | 104653-34-1 | 1mg | $341 | 2026-06-03 | Buy |
| TRC | TRC-D445450-10MG | Difethialone >95%(HPLC) | 104653-34-1 | 10mg | $2645 | 2026-06-03 | Buy |
| Biosynth | FD21844 | Difethialone | 104653-34-1 | 1mg | $623.39 | 2026-06-04 | Buy |
| Biosynth | FD21844 | Difethialone | 104653-34-1 | 2mg | $1187.4 | 2026-06-04 | Buy |
DIFETHIALONE Chemical Properties, Uses, Production
Description
Difethialone[104653-34-1], 3-[(1RS,3RS; 1RS,3SR)-3- (4 -bromobiphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl]- 4-hydroxy-1-benzothiin-2-one, C31H23BrO2S, MW 539.5, mp 233–236 C, is a slightly yellowish powder which is practically insoluble in water, moderately soluble in ethanol, methanol, hexane, acetone, readily soluble in chloroform, dimethylformamide [9, p. 393].
Uses
Difethialone is an anticoagulant rodenticide widely used to control rodent infestations.
Uses
Pesticide.
Preparation
Difethialone is made by condensation of 4-hydroxy-2H- 1-benzothiapyran-2-one with 3-(4 -bromo-4-biphenyl)-1,2, 3,4-tetrahydro-1-naphthol in acetic acid containing concentrated sulfuric acid (62).
Definition
ChEBI: Difethialone is a member of benzenes, a member of naphthalenes and a ring assembly.
Agricultural Uses
Rodenticide, Pesticide: Introduced in 1986, this second-generation anticoagulant rodenticide (member of the hydroxy-4-benzothiopyranone family) is used to control mice and rats, including those resistant to first-generation anticoagulants. Not approved for use in most EU countries. Approved for use in the U.S.
Trade name
LM-2219®; PROTECTA RAT BAIT STATION®; VETERAN PELLET®; VETERAN WAX BLOCK®
Mechanism of action
Difethialone is an anticoagulant rodenticide that disrupts the normal blood clotting mechanisms in its target species. It works by inhibiting the enzyme Vitamin K epoxide reductase (VKORC1), which is crucial for the synthesis of blood clotting factors resulting in an increased bleeding tendency and eventually death.
Pesticide Type
Rodenticide
DIFETHIALONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15350 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4508 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shandong Xiya Chemical Co., Ltd. | 4009903999 13395398332 | sales@xiyashiji.com | China | 20788 | 60 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9609 | 60 |
| Shandong Ono Chemical Co., Ltd. | 0539-6362799 20） | China | 9998 | 58 | |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| Shanghai Youde Chemical Technology Co., Ltd. | 021-37910267 15821801668 | sales@udchem.com | China | 1216 | 58 |
View Latest Price from DIFETHIALONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | DIFETHIALONE
104653-34-1
|
1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd |
-
- DIFETHIALONE
104653-34-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
