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Mal-Amido-PEG4-acid

Mal-Amido-PEG4-acid structure

CAS No.: 1263045-16-4

Chemical Name:: Mal-Amido-PEG4-acid

Synonyms: 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic acid;BMPA-PEG4-Acid;Mal-NH-PEG4-COOH;Mal-NH-PEG4-acid;MAL-amido-PEG4-PA;Mal-Amido-PEG4-acid;MAL-AMIDO-PEG4-COOH;Amido Mal-PEG4-Acid;Mal-dPEG4-CH2CH2COOH;Mal-NH-PEG4-CH2CH2COOH

CBNumber:: CB03062522

Molecular Formula:: C18H28N2O9

Molecular Weight:: 416.42

MDL Number:: MFCD13184954

MOL File:: 1263045-16-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid >95.0%(HPLC)	M2666	25mg	$44
19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid >95.0%(HPLC)	M2666	100mg	$123
MAL-dPEG®4-Acid	DPG-6205	100mg	$165
MAL-dPEG®4-Acid	DPG-6205	1000mg	$210
m-dPEG®2-NHS Ester	DPG-6124	100mg	$165
More product size

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Mal-Amido-PEG4-acid Properties

Boiling point	659.1±55.0 °C(Predicted)
Density	1.270±0.06 g/cm3(Predicted)
storage temp.	-20°C, protect from light
solubility	Soluble in Water, DMSO, DMF, DCM
form	powder to crystal
pka	4.28±0.10(Predicted)
color	White to Gray to Brown
InChI	InChI=1S/C18H28N2O9/c21-15(3-6-20-16(22)1-2-17(20)23)19-5-8-27-10-12-29-14-13-28-11-9-26-7-4-18(24)25/h1-2H,3-14H2,(H,19,21)(H,24,25)
InChIKey	IAJVEYLYYHOZEY-UHFFFAOYSA-N
SMILES	C(O)(=O)CCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O
CAS DataBase Reference	1263045-16-4

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P280-P302+P352-P362+P364

HS Code

3822000000

NFPA 704

	0
2		0

Mal-Amido-PEG4-acid price More Price(45)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	M2666	19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid >95.0%(HPLC)	1263045-16-4	25mg	$44	2026-04-30	Buy
TCI Chemical	M2666	19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid >95.0%(HPLC)	1263045-16-4	100mg	$123	2026-04-30	Buy
Biosynth	DPG-6205	MAL-dPEG®4-Acid	1263045-16-4	100mg	$165	2026-06-04	Buy
Biosynth	DPG-6205	MAL-dPEG®4-Acid	1263045-16-4	1000mg	$210	2026-06-04	Buy
Biosynth	DPG-6124	m-dPEG®2-NHS Ester	1263045-16-4	100mg	$165	2026-06-04	Buy

Product number	Packaging	Price	Buy
M2666	25mg	$44	Buy
M2666	100mg	$123	Buy
DPG-6205	100mg	$165	Buy
DPG-6205	1000mg	$210	Buy
DPG-6124	100mg	$165	Buy

Mal-Amido-PEG4-acid Chemical Properties,Uses,Production

Description

Mal-amido-PEG4-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-amido-PEG4-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Mal-Amido-PEG4-acid synthesis

Synthesis of Mal-Amido-PEG4-acid from N-Succinimidyl 3-maleimidopropionate and 15-(Boc-amino)-4,7,10,13-tetraoxapentadecanoic acid

Mal-Amido-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Maleimide-PEG4-NHS Ester

Mal-Amido-PEG4-acid Suppliers

Global( 100)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
LAURENT	+86-18100176782	sun@laurentpeg.com	China	365	58
9i LLC	+18039569191	MWan@NiNeiLab.com	United States	418	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413	contact@trustwe.com	China	5742	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 15616186207	changaiwei@sinopeg.com	China	1133	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19904	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Jilin Chinese Academy of Sciences-yanshen Technology	18143011203	info@chemextension.com	China	42052	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068	1924344760@confluore.cn	China	2996	58

Supplier	Advantage
LAURENT	58
9i LLC	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
Nextpeptide Inc	58
TargetMol Chemicals Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Xian confluore Biological Technology Co., Ltd.	58

View Lastest Price from Mal-Amido-PEG4-acid manufacturers

Update time	Product	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Mal-amido-PEG4-acid 1263045-16-4			10g	TargetMol Chemicals Inc.
2026-01-28	Mal-NH-PEG4-CH2CH2COOH 1263045-16-4	1g	98%	300kg	LAURENT
2025-06-07	Mal-amido-PEG4-acid 1263045-16-4	1g	>98.00%	1g	Xian confluore Biological Technology Co., Ltd.

Mal-amido-PEG4-acid
1263045-16-4
$0.00
TargetMol Chemicals Inc.

Mal-NH-PEG4-CH2CH2COOH
1263045-16-4
98%
LAURENT

Mal-amido-PEG4-acid
1263045-16-4
$0.00
>98.00%
Xian confluore Biological Technology Co., Ltd.

Mal-Amido-PEG4-acid Spectrum

Mal-Amido-PEG4-acid(1263045-16-4)¹HNMR Mal-Amido-PEG4-acid(1263045-16-4)¹HNMR Mal-Amido-PEG4-acid(1263045-16-4)¹³CNMR

1263045-16-4(Mal-Amido-PEG4-acid)Related Search:

alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol) alpha-MaleiMidopropionyl-oMega-succiniMidyl-6(ethylene glycol) Mal-PEG2-amine Mal-PEG3-NHS ester Mal-PEG6-COOH

N-Succinimidyl 3-maleimidopropionate Mal-PEG4-NHS ester 3,4-Dibromo-Mal-PEG2-Amine Maleimido-Tri(Ethylene Glycol)-Propionic Acid Mal-PEG2-COOH

N-[4-(-Carboxycyclohexylmethyl)]maleimide Mal-PEG4-Acid Mal-PEG2-NHS ester Bis-Mal-Lysine-PEG4-TFP ester Maleimide-PEG4-NHS Ester

Maleimide-PEG2-NHS Ester 3-Maleimidopropionic acid Mal-PEG2-acid

1of4

Mal-CH2CH2CONH-PEG4-CH2CH2COOH 1-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oic acid 19-Maleimido-17-oxo-4,7,10,13-tetraoxa-16-azanonadecanoic Acid Maleimide-NH-PEG4-CH2CH2COOH Maleimide-PEG4-propionic acid MAL-AMIDO-PEG4-COOH Mal-NH-PEG4-COOH Mal-Amido-PEG4-acid Mal-NH-PEG4-acid 4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo- Mal-amido-PEG4-propionic acid 1-Maleimido-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic Acid BMPA-PEG4-Acid Mal-CH2CH2CONH-PEG4-CH2CH2COOH/4,7,10,13-Tetraoxa-16-azanonadecanoic acid, 19-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-17-oxo- 3-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid Mal-dPEG4-CH2CH2COOH MAL-dPEG??-acid (QBD-10338) 3-Amino(peg4)propionic acid 3-maleimidopropionamide Mal-NH-PEG4-CH2CH2COOH MAL-amido-PEG4-PA Amido Mal-PEG4-Acid 1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16-tetraoxa-4-azanonadecan-19-oic acid 1263045-16-4 C18H28N2O9 peg