5-Phenyl-isoxazole-3-carboxylic acid methyl ester
- CAS No.
- 51677-09-9
- Chemical Name:
- 5-Phenyl-isoxazole-3-carboxylic acid methyl ester
- Synonyms
- AKOS B024670;AKOS BBS-00002559;ART-CHEM-BB B024670;TIMTEC-BB SBB009684;5-phenylisoxazole-3-carboxylate;3-(Methoxycarbonyl)-5-phenylisoxazole;METHYL 5-PHENYL-3-ISOXAZOLECARBOXYLATE;METHYL 5-PHENYLISOXAZOLE-3-CARBOXYLATE;Methyl 5-phenyl-1,2-oxazole-3-carboxylate;5-Phenyl-3-isoxazolecarboxylic acid methyl ester
- CBNumber:
- CB0350037
- Molecular Formula:
- C11H9NO3
- Molecular Weight:
- 203.19
- MDL Number:
- MFCD02159553
- MOL File:
- 51677-09-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 81°C |
|---|---|
| Boiling point | 370.2±30.0 °C(Predicted) |
| Density | 1.204±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | solid |
| pka | -6.43±0.28(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C11H9NO3/c1-14-11(13)9-7-10(15-12-9)8-5-3-2-4-6-8/h2-7H,1H3 |
| InChIKey | XMPLCJOQBDGMKT-UHFFFAOYSA-N |
| SMILES | COC(=O)c1cc(on1)-c2ccccc2 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Hazard Codes | Xi |
|---|---|
| HazardClass | IRRITANT |
| HS Code | 2934999090 |
| Storage Class | 11 - Combustible Solids |
5-Phenyl-isoxazole-3-carboxylic acid methyl ester price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | JRD0175 | Methyl 5-phenylisoxazole-3-carboxylate Aldrich | 51677-09-9 | 1g | $197 | 2026-04-30 | Buy |
| Apolloscientific | OR15349 | Methyl 5-phenylisoxazole-3-carboxylate >98% | 51677-09-9 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR15349 | Methyl 5-phenylisoxazole-3-carboxylate >98% | 51677-09-9 | 1g | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR15349 | Methyl 5-phenylisoxazole-3-carboxylate >98% | 51677-09-9 | 5g | $128 | 2026-06-04 | Buy |
| Apolloscientific | OR15349 | Methyl 5-phenylisoxazole-3-carboxylate >98% | 51677-09-9 | 25g | $634 | 2026-06-04 | Buy |
5-Phenyl-isoxazole-3-carboxylic acid methyl ester Chemical Properties,Uses,Production
Uses
Methyl 5-Phenylisoxazole-3-carboxylate is a useful reagent for reactions with isoxazoles.
Synthesis
![3-Butynoic acid, 4-phenyl-2-[(phenylmethoxy)imino]-, methyl ester, (2E)-](/CAS/20210305/GIF/1313396-20-1.gif)
1313396-20-1
51677-09-9
GENERAL METHODS: Alkyne oxime ether 1 (0.15 mmol) was dissolved in THF (5 mL) and phenol (28 mg, 0.3 mmol) and AgBF4 (5.8 mg, 0.03 mmol) were added sequentially. The reaction system was equipped with a drying tube (filled with silica gel) and heated to reflux at 50 °C in an oil bath. The reaction process was monitored by TLC with continuous stirring for 1-12 hours. After completion of the reaction, the reaction mixture was concentrated under reduced pressure. The residue was purified by preparative thin layer chromatography (unfolding reagent: hexane/ethyl acetate = 3-10:1) to afford the target product methyl 5-phenylisoxazole-3-carboxylate (3a and 3j). The physical properties and spectral data of the obtained compounds were in agreement with those reported in the literature.
References
[1] Tetrahedron, 2011, vol. 67, # 25, p. 4612 - 4615
5-Phenyl-isoxazole-3-carboxylic acid methyl ester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Runpharm Technology Limited | 18171398856 2968382473 | service@runpharm.com | China | 716 | 55 |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Shanghai ChriChem Co., Ltd. | 021-54880687 | China | 510 | 55 |
View Lastest Price from 5-Phenyl-isoxazole-3-carboxylic acid methyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 5-PHENYL-ISOXAZOLE-3-CARBOXYLIC ACID METHYL ESTER
51677-09-9
|
1KG | 98%; 99% | 500g； 1kg; 25kg | Career Henan Chemical Co | ||
 |
2020-01-05 | 5-PHENYL-ISOXAZOLE-3-CARBOXYLIC ACID METHYL ESTER
51677-09-9
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 5-PHENYL-ISOXAZOLE-3-CARBOXYLIC ACID METHYL ESTER
51677-09-9
- $0.01
- 98%; 99%
- Career Henan Chemical Co
-
- 5-PHENYL-ISOXAZOLE-3-CARBOXYLIC ACID METHYL ESTER
51677-09-9
- $1.00
- 99%
- Career Henan Chemical Co
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