5-Phenylisoxazole-3-carboxylic acid
- CAS No.
- 14441-90-8
- Chemical Name:
- 5-Phenylisoxazole-3-carboxylic acid
- Synonyms
- AIDS343235;AIDS-343235;AKOS B019304;AKOS PAO-1380;CHEMBRDG-BB 4401205;ART-CHEM-BB B019304;SALOR-INT L482528-1EA;5-Phenylisoxazole-3-carboxylic;5-phenyl-3-isoxazolecarboxylate;5-PHENYL-3-ISOXAZOLECARBOXYLIC ACID
- CBNumber:
- CB3449446
- Molecular Formula:
- C10H7NO3
- Molecular Weight:
- 189.17
- MDL Number:
- MFCD00464221
- MOL File:
- 14441-90-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 160-164 °C(lit.) |
|---|---|
| Boiling point | 434.7±33.0 °C(Predicted) |
| Density | 1.320 |
| storage temp. | 2-8°C |
| solubility | soluble in Methanol |
| pka | 3.33±0.10(Predicted) |
| form | Crystalline |
| color | White |
| InChI | InChI=1S/C10H7NO3/c12-10(13)8-6-9(14-11-8)7-4-2-1-3-5-7/h1-6H,(H,12,13) |
| InChIKey | XJYOBHXWBRKOQO-UHFFFAOYSA-N |
| SMILES | O1C(C2=CC=CC=C2)=CC(C(O)=O)=N1 |
| CAS DataBase Reference | 14441-90-8(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H317-H319-H334-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-42/43 | |||||||||
| Safety Statements | 26-36-45 | |||||||||
| WGK Germany | 2 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2934999090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Resp. Sens. 1 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
|||||||||
| NFPA 704 |
|
5-Phenylisoxazole-3-carboxylic acid price More Price(74)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 645087 | 5-Phenylisoxazole-3-carboxylic acid 97% | 14441-90-8 | 5g | $227 | 2026-04-30 | Buy |
| Sigma-Aldrich | 645087 | 5-Phenylisoxazole-3-carboxylic acid 97% | 14441-90-8 | 1g | $59.4 | 2023-06-20 | Buy |
| TCI Chemical | P2020 | 5-Phenylisoxazole-3-carboxylic Acid >98.0%(HPLC)(T) | 14441-90-8 | 1g | $91 | 2026-04-30 | Buy |
| TCI Chemical | P2020 | 5-Phenylisoxazole-3-carboxylic Acid >98.0%(HPLC)(T) | 14441-90-8 | 5g | $272 | 2026-04-30 | Buy |
| Usbiological | 288327 | 5-Phenylisoxazole-3-carboxylic acid Asreported | 14441-90-8 | 2g | $375 | 2026-06-03 | Buy |
5-Phenylisoxazole-3-carboxylic acid Chemical Properties,Uses,Production
Synthesis
The target compound 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID was prepared by hydrolysis using 5-phenyl-3-isoxazole carboxylic acid ester as the starting material [1]. The synthetic reaction formula is shown in the figure below:
Uses
5-Phenylacetic acid is a carboxylic acid derivative that can be used as an intermediate in organic synthesis.
Description
5-Phenylisoxazole-3-carboxylic acid is a phenoxy compound, can be used in pharmaceutical research.
Biological Activity
5-phenylisoxazole-3-carboxylic acid and derivatives have the ability to inhibit xanthine oxidase (XO). XO is a key enzyme in the last two steps of purine metabolic pathway, catalyzing the oxidation of hypoxanthine to xanthine, and then to urid acid, which associated with gout and hyperuricemia.
Safety
5-Phenylisoxazole-3-carboxylic acid is a compound that is irritating to humans. It is acutely toxic if ingested. Skin contact causes skin irritation and may also trigger allergic skin reactions. Accidental contact with the eyes may cause severe eye irritation. Inhalation may cause allergic reactions, asthma symptoms or breathing difficulties.
5-Phenylisoxazole-3-carboxylic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
5-Phenylisoxazole-3-carboxylic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Wuhan Topule | +86-02787215551 19945035818 | 2936752263@qq.com | China | 7985 | 58 |
| Jinan Guangchen Pharmaceutical Technology Co., Ltd | 18563726319 | 2845578351@qq.com | China | 7026 | 58 |
| Shanghai Hebiceng Pharmaceutical Technology Co., Ltd | 19564164886 13701791899 | 28533917@qq.com | China | 234 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 |
View Lastest Price from 5-Phenylisoxazole-3-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID
14441-90-8
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 5-PHENYLISOXAZOLE-3-CARBOXYLIC ACID
14441-90-8
- $1.00
- 99%
- Career Henan Chemical Co
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