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(+)-MAGNOFLORINE IODIDE

CAS No.
2141-09-5
Chemical Name:
(+)-MAGNOFLORINE IODIDE
Synonyms
escholin;Esholine;escholine;THALICTRIN;Aids002649;Magflorine;THALICTRINE;Aids-002649;MAGNOFLORINE;(+)-Magnoflorine
CBNumber:
CB0350572
Molecular Formula:
C20H24INO4
Molecular Weight:
469.31
MDL Number:
MFCD03427294
MOL File:
2141-09-5.mol
MSDS File:
SDS
Last updated:2025-10-16 15:39:32
Product description Number Pack Size Price
Magnoflorine ≥98% (HPLC) SMB00377 10 mg $180
Magnoflorine ≥98% 25122 5mg $97
Magnoflorine ≥98% 25122 10mg $145
Magnoflorine ≥98% 25122 25mg $337
Magnoflorine ≥98% 25122 50mg $625
More product size

(+)-MAGNOFLORINE IODIDE Properties

Melting point 252℃
storage temp. 2-8°C(protect from light)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
FDA UNII NI8K6962K4

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H315-H319-H341
Precautionary statements  P501-P202-P201-P264-P280-P302+P352-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405
NFPA 704
0
2 0

(+)-MAGNOFLORINE IODIDE price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00377 Magnoflorine ≥98% (HPLC) 2141-09-5 10 mg $180 2025-07-31 Buy
Cayman Chemical 25122 Magnoflorine ≥98% 2141-09-5 5mg $97 2024-03-01 Buy
Cayman Chemical 25122 Magnoflorine ≥98% 2141-09-5 10mg $145 2024-03-01 Buy
Cayman Chemical 25122 Magnoflorine ≥98% 2141-09-5 25mg $337 2024-03-01 Buy
Cayman Chemical 25122 Magnoflorine ≥98% 2141-09-5 50mg $625 2024-03-01 Buy
Product number Packaging Price Buy
SMB00377 10 mg $180 Buy
25122 5mg $97 Buy
25122 10mg $145 Buy
25122 25mg $337 Buy
25122 50mg $625 Buy

(+)-MAGNOFLORINE IODIDE Chemical Properties,Uses,Production

Description

A wide variety of species contain this quaternary alkaloid which is widespread among the families, Aquilegia, Magnolia and Michelia. It has been isolated and characterized as the iodide, m.p. 248-9°C (dec.); [0:11>5 + 200.1° (MeOH). The optically inactive base also yields an iodide which crystallizes with 1.5 H20, m.p. 243°C (dec.).

Description

Magnoflorine is an alkaloid and a major constituent of S. acutum that has diverse biological activities. It reduces hemolysis induced by lysophosphatidylcholine (LPC), but not NaCl, in a rat erythrocyte suspension when used at concentrations ranging from 0.01 to 10 μM. Magnoflorine (10 μM) induces intracellular chloride influx in neuroblastoma cells, an effect that is reversed by the GABAA receptor antagonist bicuculline . It reduces TNF-α-induced NF-κB expression as well as production of IL-6 and IL-8 in BEAS-2B cells. In vivo, magnoflorine (20 mg/kg, i.p.) improves short- and long-term memory acquisition in a passive avoidance test in a mouse model of scopolamine-induced memory impairment.

Uses

Magnoflorine-d3 is the labelled analogue of Magnoflorine, an isoquinoline alkaloid from the Coptis japonica and it enhances the myoblast differentiation through activation of the p38 MAP kinase and Akt pathway.

Definition

ChEBI: (S)-magnoflorine is an aporphine alkaloid that is (S)-corytuberine in which the nitrogen has been quaternised by an additional methyl group. It has a role as a plant metabolite. It is an aporphine alkaloid and a quaternary ammonium ion. It is functionally related to a (S)-corytuberine.

References

Nakano., Chem. Pharm. Bull. (Tokyo), 2, 329 (1954) Tomita, Kikkawa.,J. Pharm. Soc., Japan, 77, 195 (1957) Gopinath et aI., J. Sci. Ind. Res., 18B, 444 (1959) Ishii, Harada.,J. Pharm. Soc., Japan, 81,238 (1961) Yang, Lu, Hsiao., ibid, 82,794,816 (1962) Yang, Lu, Hsiao., ibid, 83,216 (1963)

(+)-MAGNOFLORINE IODIDE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 189)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907 qinhe02@xaltbio.com China 997 58
ATK CHEMICAL COMPANY LIMITED
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Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
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Chengdu GLP biotechnology Co Ltd
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Chengdu Biopurify Phytochemicals Ltd.
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Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58

View Lastest Price from (+)-MAGNOFLORINE IODIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(+)-Magnoflorine pictures 2025-10-16 (+)-Magnoflorine
2141-09-5
US $290.00 / mg 99.70% 10g TargetMol Chemicals Inc.
magnoflorine pictures 2024-04-12 magnoflorine
2141-09-5
US $0.00 / kg 1kg 99% 2000ton Shaanxi Haibo Biotechnology Co., Ltd
Magnoflorine pictures 2023-02-24 Magnoflorine
2141-09-5
US $0.00 / mg 20mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • magnoflorine pictures
  • magnoflorine
    2141-09-5
  • US $0.00 / kg
  • 99%
  • Shaanxi Haibo Biotechnology Co., Ltd
  • Magnoflorine pictures
  • Magnoflorine
    2141-09-5
  • US $0.00 / mg
  • ≥98%(HPLC)
  • Shanghai Standard Technology Co., Ltd.
MAGNOFLORINE (+)-MAGNOFLORINE IODIDE MAGNOFLORINE IODIDE, (+)- 1,11-dihydroxy-2,10-dimethoxy-6-methyl-6a-alpha-aporphiniu escholin escholine g)quinolinium,5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-4h-dibenzo(d THALICTRIN THALICTRINE (6aS)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6aα,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium Corytuberine Methosalt Esholine (6aS)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium [6aS,(+)]-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium 5,6,6A(S),7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,G]quinolinium chloride Aids002649 Aids-002649 Aporphine alkaloid Magflorine alpha-Magnoflorine (+)-Magnoflorine (6aS)-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-6-ium-1,11-diol (S)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-6-ium (+)-Magnoflorine, 10 mM in DMSO (+)-MAGNOFLORINE IODIDE 2141-09-5 2041-09-5 C33H45NO11I C20H24NO4X C16H24NO4 C20H24INO4 Alkaloids