Ethyl 2-aminopyridine-3-carboxylate
- CAS No.
- 13362-26-0
- Chemical Name:
- Ethyl 2-aminopyridine-3-carboxylate
- Synonyms
- ETHYL 2-AMINONICOTINATE;AKOS 90517;BUTTPARK 23\07-65;RARECHEM AL BI 1234;Nicorandil Impurity 47;Ethyl2-Aminonicotinate>Nicotinic Acid Impurity 12;Nicotinic acid Impurity 10;Ethyl 2-aMinonicotinic acid;Ethyl 2-aminonicotinate ,97%
- CBNumber:
- CB0352475
- Molecular Formula:
- C8H10N2O2
- Molecular Weight:
- 166.18
- MDL Number:
- MFCD01569452
- MOL File:
- 13362-26-0.mol
- MSDS File:
- SDS
| Melting point | 96-98°C |
|---|---|
| Boiling point | 133°C/12mmHg(lit.) |
| Density | 1.192±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO, Methanol |
| pka | 4.84±0.36(Predicted) |
| form | Solid |
| color | Yellow |
| InChI | InChI=1S/C8H10N2O2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3,(H2,9,10) |
| InChIKey | KIAGEDYOPMHRRB-UHFFFAOYSA-N |
| SMILES | C1(N)=NC=CC=C1C(OCC)=O |
| CAS DataBase Reference | 13362-26-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
Ethyl 2-aminopyridine-3-carboxylate price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | E1146 | Ethyl 2-Aminonicotinate >98.0%(GC)(T) | 13362-26-0 | 1g | $34 | 2026-04-30 | Buy |
| TCI Chemical | E1146 | Ethyl 2-Aminonicotinate >98.0%(GC)(T) | 13362-26-0 | 5g | $136 | 2026-04-30 | Buy |
| AstaTech | CL0048 | ETHYL2-AMINONICOTINATE 97% | 13362-26-0 | 5G | $15 | 2026-04-30 | Buy |
| Apolloscientific | OR15285 | Ethyl 2-aminonicotinate 98% | 13362-26-0 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR15285 | Ethyl 2-aminonicotinate 98% | 13362-26-0 | 25g | $69 | 2026-06-04 | Buy |
Ethyl 2-aminopyridine-3-carboxylate Chemical Properties, Uses, Production
Chemical Properties
Yellow Solid
Uses
A pyrimidine derivative with diuretic activity.
Synthesis
5345-47-1
64-17-5
13362-26-0
2-Aminonicotinic acid (1) (5 g, 36 mmol) and ethanol (100 mL) were used as feedstock to which concentrated sulfuric acid (10 mL) was added. The reaction mixture was heated to reflux for 16 hours and subsequently cooled to room temperature. The completion of the reaction was confirmed by LC-MS analysis. The volatiles were removed under vacuum, water was added, and the crude product was alkalized with 1N NaOH solution to pH 8.0. The product was extracted twice with ethyl acetate, and the organic phases were combined, dried over magnesium sulfate, and then concentrated to afford ethyl (2) 2-aminonicotinate (6.0 g, 100% yield) as a white crystalline solid. hplc-ms analysis results: retention time t R = 0.41 min (UV 254 nm); mass calculated value C8H10N2O2 166.1, measured value LCMS m/z 167.1 (M + H).
References
[1] Patent: WO2008/82490, 2008, A2. Location in patent: Page/Page column 70
[2] Patent: TWI525093, 2016, B. Location in patent: Page/Page column 101;
[3] Patent: WO2007/67416, 2007, A2. Location in patent: Page/Page column 64; 134
[4] Patent: WO2007/86080, 2007, A2. Location in patent: Page/Page column 37
[5] Heterocycles, 1993, vol. 36, # 11, p. 2513 - 2522
Ethyl 2-aminopyridine-3-carboxylate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shijiazhuang Coshine Chemical Co.,Ltd | 18633820607 18633820607 | 377964081@qq.com | China | 94 | 58 |
| Shijiazhuang C-element Biotech Co.,Ltd | +86-18033710157 18033710157 | Lisa@C-elementBiotech.com | China | 234 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from Ethyl 2-aminopyridine-3-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Ethyl 2-aminopyridine-3-carboxylate
13362-26-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2026-07-01 | Ethyl 2-aminopyridine-3-carboxylate
13362-26-0
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2026-07-01 | Ethyl 2-aminonicotinate
13362-26-0
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd |
-
- Ethyl 2-aminopyridine-3-carboxylate
13362-26-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Ethyl 2-aminopyridine-3-carboxylate
13362-26-0
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- Ethyl 2-aminonicotinate
13362-26-0
- 98%
- Shaanxi Dideu New Materials Co. Ltd
