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RO-31-8425

RO-31-8425 Structure
RO-31-8425 structure
CAS No.
131848-97-0
Chemical Name:
RO-31-8425
Synonyms
Ro 31-8245;RO-31-8425;RSYYBisindolylmaleimideXhydrochloride;Ro-31-8425 - CAS 131848-97-0 - Calbiochem;BisindolylMaleiMide X . hydrochloride [Ro 31-8425];3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-
CBNumber:
CB0353038
Molecular Formula:
C26H24N4O2
Molecular Weight:
424.49
MDL Number:
MFCD04972010
MOL File:
131848-97-0.mol
Last updated:2025-01-27 09:38:02
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RO-31-8425 Properties

Boiling point 736.1±60.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility DMSO: 10mg/mL
form Red to orange-red solid
pka 7.91±0.60(Predicted)
color red to orange-red
UNSPSC Code 12352200
NACRES NA.77

SAFETY

Risk and Safety Statements

HS Code  2925199590

RO-31-8425 price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 557514 Ro-31-8425 131848-97-0 1mg $163 2025-07-31 Buy
Iris Biotech GmbH LS-4080 BisindolylmaleimideX 131848-97-0 1mg $270 2021-12-16 Buy
American Custom Chemicals Corporation INB0009782 BISINDOLYLMALEIMIDE X 95.00% 131848-97-0 5MG $516 2021-12-16 Buy
Product number Packaging Price Buy
557514 1mg $163 Buy
LS-4080 1mg $270 Buy
INB0009782 5MG $516 Buy

RO-31-8425 Chemical Properties,Uses,Production

Uses

Bisindolylmaleimide X is a selective inhibitor of PKC, also inhibits Cdk2 and GSK-3β.

Biological Activity

Cell permeable: yes', 'Primary Target
PKC', 'Product competes with ATP.', 'Reversible: yes', 'Target IC50: 15 nM for r at brain PKC; 8 nM for PKCα, 8 nM for PKCβI, 14 nM for PKCβII, 13 nM for PKCγ, and 39 nM for PKCε

RO-31-8425 Preparation Products And Raw materials

Raw materials

Preparation Products

RO-31-8425 Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
TOSUN PHARM 020-61855200 13326451905 260366801@qq.com China 7903 58
Jinan Ruisi Pharmaceutical Technology Co., LTD 0531-69900633 18340090523 changyuan20@163.com China 2739 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44814 58
Adipogen Life Sciences 41-6192660-40 info@adipogen.com China 5293 58
Merck Millipore 1-400-889-1988 400-889-1988 bioscience@merckgroup.com China 6839 58
Merck KGaA 21-20338288 ordercn@merckgroup.com China 6394 58
Supplier Advantage
Aladdin Scientific 		58
TOSUN PHARM 58
Jinan Ruisi Pharmaceutical Technology Co., LTD 58
Energy Chemical 58
Adipogen Life Sciences 58
Merck Millipore 58
Merck KGaA 58

131848-97-0(RO-31-8425)Related Search:

RO-31-8425,RO 31-8425 HYDROCHLORIDE,RO 31 8425 HCL RO-32-0432 RO-31-8425
RO-31-8425 BisindolylMaleiMide X . hydrochloride [Ro 31-8425] 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Ro 31-8245 Ro-31-8425 - CAS 131848-97-0 - Calbiochem RSYYBisindolylmaleimideXhydrochloride 1H-Pyrrole-2,5-dione, 3-[8-(aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)- 131848-97-0 C26H24N4O2 C26H24N4O2HCl inhibitor