Ethyl L-valinate hydrochloride
- CAS No.
- 17609-47-1
- Chemical Name:
- Ethyl L-valinate hydrochloride
- Synonyms
- H-VAL-OET HCL;ine ethyL;H-VAL-OET·HCL;L-Val-OEt.HCL;VALINE-OET HCL;H-L-Val-OEt*HCl;Exemestane Impurity 48;H-VAL-OET HYDROCHLORIDE;L-VALINE ETHYL ESTER HCL;L-valinate hydrochloride
- CBNumber:
- CB0362847
- Molecular Formula:
- C7H16ClNO2
- Molecular Weight:
- 181.66
- MDL Number:
- MFCD00012511
- MOL File:
- 17609-47-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 102-105 °C(lit.) |
|---|---|
| alpha | 7 º (c=2, H2O) |
| storage temp. | Sealed in dry,Room Temperature |
| Water Solubility | Soluble in water |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | powder to crystal |
| color | White to Almost white |
| optical activity | [α]20/D +6.7°, c = 2 in H2O |
| Major Application | peptide synthesis |
| InChI | InChI=1/C7H15NO2.ClH/c1-4-10-7(9)6(8)5(2)3;/h5-6H,4,8H2,1-3H3;1H/t6-;/s3 |
| InChIKey | PQGVTLQEKCJXKF-RGMNGODLSA-N |
| SMILES | [C@H](N)(C(C)C)C(=O)OCC.Cl |&1:0,r| |
| CAS DataBase Reference | 17609-47-1(CAS DataBase Reference) |
| UNSPSC Code | 12352209 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H336 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P301+P312+P330-P304+P340+P312-P403+P233-P405 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | Xi | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29224999 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
Ethyl L-valinate hydrochloride price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 220698 | L-Valine ethyl ester hydrochloride 99% | 17609-47-1 | 5g | $77.9 | 2026-04-30 | Buy |
| TCI Chemical | V0142 | L-Valine Ethyl Ester Hydrochloride >98.0%(T) | 17609-47-1 | 5g | $23 | 2026-04-30 | Buy |
| TCI Chemical | V0142 | L-Valine Ethyl Ester Hydrochloride >98.0%(T) | 17609-47-1 | 25g | $53 | 2026-04-30 | Buy |
| Usbiological | V1020-30 | Valine Ethyl Ester, Hydrochloride | 17609-47-1 | 1g | $403 | 2026-06-04 | Buy |
| Usbiological | 291972 | L-Valine ethyl ester HCI Asreported | 17609-47-1 | 250g | $386 | 2026-06-03 | Buy |
Ethyl L-valinate hydrochloride Chemical Properties, Uses, Production
Chemical Properties
white crystalline powder
Uses
peptide synthesis
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
64-17-5
72-18-4
17609-47-1
The general procedure for the synthesis of L-valine ethyl ester hydrochloride from ethanol and L-valine is as follows: 5 kg (42.7 mol) of L-valine and 4 kg of anhydrous ethanol were added to a 50-liter glass reactor and stirred until complete dissolution. After cooling the reaction mixture to 0-10°C, 8.8 liters of thionyl chloride were added slowly and dropwise. After the dropwise addition was completed, the reaction mixture was gradually heated to reflux and the reaction was maintained for 18 hours. Upon completion of the reaction, the reaction solution was concentrated to dryness. Subsequently, 15 liters of isopropyl acetate was added to the dried residue at 15 to 20°C and stirred for 1 hour. Finally, the product was collected by diafiltration to give 6.1 kg of off-white solid, Intermediate 1 (where R1 is ethyl).
References
[1] Tetrahedron, 2005, vol. 61, # 35, p. 8423 - 8442
[2] Journal of the Indian Chemical Society, 2001, vol. 78, # 3, p. 137 - 141
[3] Journal of the American Chemical Society, 2018, vol. 140, # 22, p. 6818 - 6822
[4] Chemistry of Natural Compounds, 1994, vol. 30, # 2, p. 238 - 244
[5] Khimiya Prirodnykh Soedinenii, 1994, # 2, p. 261 - 268
Ethyl L-valinate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Yangzhou Xuda Biotechnology Co., Ltd | 15161820588; 15161820588 | xdchemical2024@163.com | China | 91 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
View Latest Price from Ethyl L-valinate hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Ethyl L-valinate hydrochloride
17609-47-1
|
1KG | 98%min | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-17 | H-L-Val-OEt·HCl
17609-47-1
|
1kg | 98% | 1T+ | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
 |
2026-03-20 | Ethyl L-valinate hydrochloride
17609-47-1
|
$9.90 | 1KG | 99% | 5tons | Hebei Chuanghai Biotechnology Co., Ltd |
-
- Ethyl L-valinate hydrochloride
17609-47-1
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- H-L-Val-OEt·HCl
17609-47-1
- 98%
- Sichuan HongRi Pharma-Tech Co.,Ltd
-
- Ethyl L-valinate hydrochloride
17609-47-1
- $9.90
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
