AC-IETD-CHO
- CAS No.
- 191338-86-0
- Chemical Name:
- AC-IETD-CHO
- Synonyms
- AC-IETD-CHO;AC-IETD-ALDEHYDE;CASPASE 8 INHIBITOR 1;CASPASE-8 INHIBITOR I;AC-ILE-GLU-THR-ASP-CHO;GRANZYME B INHIBITOR II;IETD-CHO, CELL-PERMEABLE;AC-ILE-GLU-THR-ASP-ALDEHYDE;caspase-8 inhibitor inhibitor;AC-ILE-GLU-THR-ASP-H (ALDEHYDE)
- CBNumber:
- CB0372613
- Molecular Formula:
- C21H34N4O10
- Molecular Weight:
- 502.52
- MDL Number:
- MFCD01318858
- MOL File:
- 191338-86-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Caspase-8 Inhibitor I, Cell-Permeable The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications. | 218773 | 1MG | $335 |
| Ac-Ile-Glu-Thr-Asp-H (aldehyde) | ICA-3196-V | 5mg | $816.7 |
| Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | FA111074 | 10mg | $900 |
| Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | FA111074 | 5mg | $900 |
| Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | FA111074 | 2mg | $900 |
| More product size | |||
| Boiling point | 971.868±65.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.304±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | −20°C |
| solubility | H2O: 1 mg/mL |
| form | powder |
| pka | 4.190±0.10(predicted) |
| color | white |
| Sequence | Ac-Ile-Glu-Thr-Asp-CHO |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
AC-IETD-CHO price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 218773 | Caspase-8 Inhibitor I, Cell-Permeable The Caspase 8 Inhibitor I, Cell-Permeable controls the biological activity of Caspase-8. This small molecule/inhibitor is primarily used for Cancer applications. | 1MG | $335 | 2026-04-30 | Buy | |
| Biosynth | ICA-3196-V | Ac-Ile-Glu-Thr-Asp-H (aldehyde) | 191338-86-0 | 5mg | $816.7 | 2026-06-04 | Buy |
| Biosynth | FA111074 | Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | 191338-86-0 | 10mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA111074 | Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | 191338-86-0 | 5mg | $900 | 2026-06-04 | Buy |
| Biosynth | FA111074 | Ac-Ile-Glu-Thr-Asp-aldehyde (pseudo acid) | 191338-86-0 | 2mg | $900 | 2026-06-04 | Buy |
AC-IETD-CHO Chemical Properties,Uses,Production
Uses
Ac- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death[1][2].
Biological Activity
Cell permeable: yes', 'Primary Target
caspase-8', 'Product does not compete with ATP.', 'Reversible: yes
References
[1] Bajt ML, et al. Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8. Toxicol Sci. 2000 Nov;58(1):109-17. DOI:10.1093/toxsci/58.1.109
[2] Hayashida M, et al. Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells. Proc Soc Exp Biol Med. 2000 Nov;225(2):143-50. DOI:10.1046/j.1525-1373.2000.22518.x
AC-IETD-CHO Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11776 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29988 | 65 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7858 | 58 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
| Nanchang Tianzhen Biotechnology Co., Ltd | 13758194781 13173652190 | 522013271@qq.com | China | 2446 | 58 |
View Lastest Price from AC-IETD-CHO manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Ac-?IETD-?CHO
191338-86-0
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Ac-?IETD-?CHO
191338-86-0
- $1520.00-2500.00
- TargetMol Chemicals Inc.
