Tetrahydro-2H-pyran-4-carbonyl chloride
- CAS No.
- 40191-32-0
- Chemical Name:
- Tetrahydro-2H-pyran-4-carbonyl chloride
- Synonyms
- Tetrahydro-2H-Pyran-4-Carbonyl;Trahydr-opyran-4-carbonyl chloride;4-(Chlorocarbonyl)tetrahydro-2H-pyran;Tetrahydro-pyran-4-carbonyl chloride;Tetrahydro-2H-pyran-4-carbonyl chlorid;Tetrahydro-2H-pyrane-4-carbonylchloride;TETRAHYDRO-2H-PYRAN-4-CARBONYL CHLORIDE;2H-Pyran-4-carbonyl chloride, tetrahydro-;Tetrahydro-2H-pyran-4-carbonyl chloride 97%;tetrahydro-2H-pyran-4-carbonyl chloride
- CBNumber:
- CB0411990
- Molecular Formula:
- C6H9ClO2
- Molecular Weight:
- 148.59
- MDL Number:
- MFCD06200863
- MOL File:
- 40191-32-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 50 °C |
|---|---|
| Density | 1.201±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | clear liquid |
| color | Colorless to Almost colorless |
| InChI | 1S/C6H9ClO2/c7-6(8)5-1-3-9-4-2-5/h5H,1-4H2 |
| InChIKey | RYGUCYSSMOFTSH-UHFFFAOYSA-N |
| SMILES | ClC(=O)C1CCOCC1 |
| CAS DataBase Reference | 40191-32-0 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi,C | |||||||||
| Risk Statements | 14-20/21/22-29-34-36-52/53 | |||||||||
| Safety Statements | 23-24/25-36/37/39-45-26-61 | |||||||||
| RIDADR | 3265 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
Tetrahydro-2H-pyran-4-carbonyl chloride price More Price(75)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SYX00374 | Tetrahydro-2H-pyran-4-carbonyl chloride | 40191-32-0 | 1g | $304 | 2026-04-30 | Buy |
| TCI Chemical | T3890 | Tetrahydro-2H-pyran-4-carbonyl Chloride | 40191-32-0 | 1G | $41 | 2026-04-30 | Buy |
| TCI Chemical | T3890 | Tetrahydro-2H-pyran-4-carbonyl Chloride | 40191-32-0 | 5G | $141 | 2026-04-30 | Buy |
| Usbiological | 291404 | Tetrahydro-2H-pyran-4-carbonyl chloride Asreported | 40191-32-0 | 500mg | $340 | 2026-06-03 | Buy |
| Usbiological | 291404 | Tetrahydro-2H-pyran-4-carbonyl chloride Asreported | 40191-32-0 | 1g | $579 | 2026-06-03 | Buy |
Tetrahydro-2H-pyran-4-carbonyl chloride Chemical Properties, Uses, Production
Chemical Properties
Colorless to light yellow liquid
Synthesis
5337-03-1
40191-32-0
In a 50 mL three-necked round-bottomed flask, 6.85 g (52.6 mmol) of tetrahydropyran-4-carboxylic acid, 9.79 g (82.3 mmol) of thionyl chloride, and 10 mL of toluene were sequentially added, and a stirrer, thermometer, and reflux condenser were assembled. The reaction system was placed in an oil bath at 80 °C and the reaction was continuously stirred for 1.5 hours. At the end of the reaction, the solvent and excess thionyl chloride were removed by distillation under reduced pressure to afford 7.81 g (100% yield) of tetrahydropyran-4-carbonyl chloride as a light brown liquid. The product was characterized as follows: 1H-NMR (CDCl3, δ/ppm): 1.79-1.93 (2H, m), 1.99-2.06 (2H, m), 2.91-3.00 (1H, m), 3.40-3.49 (2H, m), 3.97-4.03 (2H, m); CI-MS (m/z): 131 [M+1]+.
References
[1] Patent: US2008/306287, 2008, A1. Location in patent: Page/Page column 6
[2] Patent: WO2008/71948, 2008, A2. Location in patent: Page/Page column 11-12
[3] Helvetica Chimica Acta, 1997, vol. 80, # 5, p. 1528 - 1551
[4] Journal of the Chemical Society, 1930, p. 2525,2529
[5] Chemical and Pharmaceutical Bulletin, 1987, vol. 35, # 6, p. 2426 - 2436
Tetrahydro-2H-pyran-4-carbonyl chloride Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Shanghai Jin Yi Fine Chemical Co.,LTD | 021-52801082 13918092929 | jinyi_service@jyfinechem.com | China | 42 | 57 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4368 | 65 |
View Latest Price from Tetrahydro-2H-pyran-4-carbonyl chloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | Tetrahydro-2H-pyran-4-carbonyl chloride
40191-32-0
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2019-07-10 | Tetrahydro-2H-pyran-4-carbonyl chloride
40191-32-0
|
$1.00 | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- Tetrahydro-2H-pyran-4-carbonyl chloride
40191-32-0
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Tetrahydro-2H-pyran-4-carbonyl chloride
40191-32-0
- $1.00
- 99%
- Career Henan Chemical Co
