4,6-Dichloro-nicotinamide
- CAS No.
- 70593-57-6
- Chemical Name:
- 4,6-Dichloro-nicotinamide
- Synonyms
- Benzopyrene Impurity 6;4,6-Dichloro-nicotinamide;4,6-DICHLORONICOTINAMIDE >95%;4,6-Dichloropyridin-3-carboxamide;4,6-DICHLOROPYRIDINE-3-CARBOXAMIDE;3-Pyridinecarboxamide, 4,6-dichloro-;4,6-DICHLORO-NICOTINAMIDE ISO 9001：2015 REACH
- CBNumber:
- CB0423715
- Molecular Formula:
- C6H4Cl2N2O
- Molecular Weight:
- 191.01
- MDL Number:
- MFCD01646073
- MOL File:
- 70593-57-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
4,6-Dichloro-nicotinamide price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR303826 | 4,6-Dichloronicotinamide 95% | 70593-57-6 | 100mg | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR303826 | 4,6-Dichloronicotinamide 95% | 70593-57-6 | 250mg | $28 | 2026-06-04 | Buy |
| Apolloscientific | OR303826 | 4,6-Dichloronicotinamide 95% | 70593-57-6 | 500mg | $32 | 2026-06-04 | Buy |
| Apolloscientific | OR303826 | 4,6-Dichloronicotinamide 95% | 70593-57-6 | 1g | $36 | 2026-06-04 | Buy |
| Synthonix | D42133 | 4,6-Dichloronicotinamide 98% | 70593-57-6 | 250mg | $47 | 2026-05-06 | Buy |
4,6-Dichloro-nicotinamide Chemical Properties, Uses, Production
Uses
4,6-Dichloronicotinamide
Synthesis
73027-79-9
70593-57-6
General procedure for the synthesis of 4,6-dichloropyridine-3-amide from 4,6-dichloronicotinic acid: oxalyl chloride (7.70 mL, 88.3 mmol) was slowly added to a suspension of 4,6-dichloronicotinic acid (8.47 g, 44.1 mmol) in dimethylformamide (200 mL) over a period of 1 h. The reaction was carried out at room temperature. After addition, the reaction mixture was continued to be stirred at room temperature for 3 hours, followed by vacuum concentration. The residue was dissolved in dichloromethane (200 mL), followed by the slow dropwise addition of ammonia (8.3 mL, 130 mmol) over a period of 30 minutes [Note: the addition of ammonia triggers an exothermic reaction, and the rate of dropwise acceleration needs to be controlled to ensure that the reaction temperature does not exceed 25°C]. After dropwise addition, the reaction mixture was continued to be stirred at room temperature for 1 hour, after which it was diluted with water (600 mL) and extracted with ethyl acetate (4 x 600 mL). The organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated to afford 4,6-dichloropyridin-3-amide as a light brown solid (8.05 g, 95% yield). The product was used for subsequent reactions without further purification.1H NMR (400 MHz, d6-DMSO) δ 8.48 (s, 1H), 8.10 (br s, 1H), 7.87 (br s, 2H).
References
[1] Patent: US2015/291629, 2015, A1. Location in patent: Paragraph 1173-1174
[2] Patent: US2006/217417, 2006, A1. Location in patent: Page/Page column 12; 13
4,6-Dichloro-nicotinamide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Accela ChemBio Co.,Ltd. | 021-50795510 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Tongchuang Pharma(Suzhou). Co., Ltd. | 0512-63263366 18912765016 | tongtf110@sina.com | China | 984 | 62 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 |
View Latest Price from 4,6-Dichloro-nicotinamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | 4,6-DICHLORO-NICOTINAMIDE
70593-57-6
|
$1.10 | 1g | 99.00% | 100 Tons min | Dideu Industries Group Limited | |
 |
2020-01-09 | 4,6-DICHLORO-NICOTINAMIDE
70593-57-6
|
$1.00 | 1ASSAYS | 85.0-99.8% | 20tons | Career Henan Chemical Co |
-
- 4,6-DICHLORO-NICOTINAMIDE
70593-57-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- 4,6-DICHLORO-NICOTINAMIDE
70593-57-6
- $1.00
- 85.0-99.8%
- Career Henan Chemical Co
