4,6-Dichloronicotinic acid
- CAS No.
- 73027-79-9
- Chemical Name:
- 4,6-Dichloronicotinic acid
- Synonyms
- 4,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID;4,6-DichloronicotinicAci;4,6-DICHLORONICOTINIC ACID;2,4-Dichloro-5-carboxypyridine;2,4-DICHLORO-5-CARBOXYLPYRIDINE;4,6-Dichloronicotinic acid ,97%;2,4-Dichloro-5-carboxylpyridine ,97%;4,6-Dichloronicotinic Acid(WX614282);4,6-Dichloropyridin-3-carboxylic acid;4,6-Dichloro-3-pyridinecarboxylic acid
- CBNumber:
- CB5449682
- Molecular Formula:
- C6H3Cl2NO2
- Molecular Weight:
- 192
- MDL Number:
- MFCD00234146
- MOL File:
- 73027-79-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4,6-Dichloronicotinic Acid >98.0%(T) | D5311 | 1g | $32 |
| 4,6-Dichloronicotinic Acid >98.0%(T) | D5311 | 5g | $126 |
| 4,6-Dichloronicotinic acid | TRC-D435638-500MG | 500mg | $97 |
| 4,6-Dichloronicotinic acid | TRC-D435638-250MG | 250mg | $84 |
| 4,6-Dichloronicotinic acid | TRC-D435638-100MG | 100mg | $72 |
| More product size | |||
| Melting point | 158-160 |
|---|---|
| Boiling point | 337.0±37.0 °C(Predicted) |
| Density | 1.612±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 1.87±0.25(Predicted) |
| form | Solid |
| color | White to Light yellow |
| Water Solubility | Slightly soluble in water. |
| Stability | Hygroscopic |
| InChI | InChI=1S/C6H3Cl2NO2/c7-4-1-5(8)9-2-3(4)6(10)11/h1-2H,(H,10,11) |
| InChIKey | ILMIEWNDXAKVNI-UHFFFAOYSA-N |
| SMILES | C1=NC(Cl)=CC(Cl)=C1C(O)=O |
| CAS DataBase Reference | 73027-79-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-20/21/22 | |||||||||
| Safety Statements | 24/25-36/37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| NFPA 704 |
|
4,6-Dichloronicotinic acid price More Price(85)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5311 | 4,6-Dichloronicotinic Acid >98.0%(T) | 73027-79-9 | 1g | $32 | 2026-04-30 | Buy |
| TCI Chemical | D5311 | 4,6-Dichloronicotinic Acid >98.0%(T) | 73027-79-9 | 5g | $126 | 2026-04-30 | Buy |
| TRC | TRC-D435638-500MG | 4,6-Dichloronicotinic acid | 73027-79-9 | 500mg | $97 | 2026-06-03 | Buy |
| TRC | TRC-D435638-250MG | 4,6-Dichloronicotinic acid | 73027-79-9 | 250mg | $84 | 2026-06-03 | Buy |
| TRC | TRC-D435638-100MG | 4,6-Dichloronicotinic acid | 73027-79-9 | 100mg | $72 | 2026-06-03 | Buy |
4,6-Dichloronicotinic acid Chemical Properties,Uses,Production
Chemical Properties
White solid
Uses
4,6-Dichloronicotinic acid is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.
Synthesis
40296-46-6
73027-79-9
General procedure for the synthesis of 4,6-dichloronicotinic acid from ethyl 4,6-dichloronicotinate: to a stirred solution of ethyl 4,6-dichloronicotinate (22) (25.95 g, 118 mmol) dissolved in 4:1:1 THF:MeOH:water (600 mL) was added sodium hydroxide solution (40 mL, 6.25 M). After 30 min of reaction, the reaction mixture was acidified to pH 2 with concentrated hydrochloric acid and subsequently diluted with 1:1 EtOAc:Et2O and washed sequentially with water and brine. The organic layer was dried over anhydrous sodium sulfate and concentrated. The resulting off-white solid was purified by concentrating twice from toluene to give the final target product 4,6-dichloronicotinic acid (23) as a white solid (21.73 g, 96% yield).
References
[1] Patent: US2005/49419, 2005, A1. Location in patent: Page/Page column 24
[2] Patent: US2005/54701, 2005, A1
[3] Tetrahedron Letters, 2011, vol. 52, # 4, p. 512 - 514
[4] Patent: WO2014/52365, 2014, A1. Location in patent: Page/Page column 229-230
[5] Patent: US2015/191464, 2015, A1. Location in patent: Paragraph 0611
4,6-Dichloronicotinic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16505 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17339 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| Chemsigma International Co., Ltd. | +86-2558742998 +86-19951791336 | info@chemsigma.com | China | 1824 | 58 |
View Lastest Price from 4,6-Dichloronicotinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-31 | 4,6-Dichloronicotinic acid
73027-79-9
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-25 | 4,6-Dichloronicotinic acid
73027-79-9
|
$3.00-9.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2026-08-20 | 4,6-Dichloronicotinic acid
73027-79-9
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 4,6-Dichloronicotinic acid
73027-79-9
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4,6-Dichloronicotinic acid
73027-79-9
- $3.00-9.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 4,6-Dichloronicotinic acid
73027-79-9
- $1.10
- 99.00%
- Dideu Industries Group Limited
