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DIETHYL 4-BROMOBENZYL PHOSPHONATE

CAS No.
38186-51-5
Chemical Name:
DIETHYL 4-BROMOBENZYL PHOSPHONATE
Synonyms
4-Bromobenzyl diethylphosphite;Diethy 4-Bromobenzyl Phosphonate;DIETHYL 4-BROMOBENZYL PHOSPHONATE;Diethyl(4-Bromobenzyl)phosphonate>4-BROMOBENZYL-PHOSPHONIC ACID DIETHYLESTER;Diethyl P-[(4-bromophenyl)methyl]phosphonate;Phosphonic acid, P-[(4-bromophenyl)methyl]-, diethyl ester
CBNumber:
CB0455086
Molecular Formula:
C11H16BrO3P
Molecular Weight:
307.12
MDL Number:
MFCD05663693
MOL File:
38186-51-5.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:42
Product description Number Pack Size Price
Diethyl (4-Bromobenzyl)phosphonate >98.0%(GC) D3688 5g $47
Diethyl (4-Bromobenzyl)phosphonate >98.0%(GC) D3688 25g $184
1-Bromo-4-(diethoxyphosphorylmethyl)benzene 206562 25.00g $307
Diethyl 4-bromobenzylphosphonate 95+% D54965 1g $17
Diethyl 4-bromobenzylphosphonate 95+% D54965 5g $20
More product size

DIETHYL 4-BROMOBENZYL PHOSPHONATE Properties

Boiling point 183 °C / 0.6mmHg
Density 1.37
refractive index 1.5230-1.5270
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Colorless to Almost colorless
CAS DataBase Reference 38186-51-5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338
HS Code  2931.90.6000
NFPA 704
0
2 0

DIETHYL 4-BROMOBENZYL PHOSPHONATE price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D3688 Diethyl (4-Bromobenzyl)phosphonate >98.0%(GC) 38186-51-5 5g $47 2026-04-30 Buy
TCI Chemical D3688 Diethyl (4-Bromobenzyl)phosphonate >98.0%(GC) 38186-51-5 25g $184 2026-04-30 Buy
Matrix Scientific 206562 1-Bromo-4-(diethoxyphosphorylmethyl)benzene 38186-51-5 25.00g $307 2026-05-18 Buy
Synthonix D54965 Diethyl 4-bromobenzylphosphonate 95+% 38186-51-5 1g $17 2026-05-06 Buy
Synthonix D54965 Diethyl 4-bromobenzylphosphonate 95+% 38186-51-5 5g $20 2026-05-06 Buy
Product number Packaging Price Buy
D3688 5g $47 Buy
D3688 25g $184 Buy
206562 25.00g $307 Buy
D54965 1g $17 Buy
D54965 5g $20 Buy

DIETHYL 4-BROMOBENZYL PHOSPHONATE Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid

Uses

Diethyl 4-Bromobenzylphosphonate can be used as a virucide.

Synthesis

4-Bromobenzyl bromide

589-15-1

Triethyl phosphite

122-52-1

DIETHYL 4-BROMOBENZYL PHOSPHONATE

38186-51-5

General procedure for the synthesis of diethyl 4-bromobenzylphosphonate (16) from p-bromobenzyl bromide and triethyl phosphite: 1-bromo-4-(bromomethyl)benzene (5.0 g, 20 mmol) and triethyl phosphite (51 mL, 300 mmol) were added to a round-bottomed flask, and the mixture was reacted by refluxing the reaction for 19 hours at 90 °C. Upon completion of the reaction, the excess triethyl phosphite was removed by distillation under reduced pressure. The crude product was purified by fast column chromatography (eluent ratio 1:1 hexane/ethyl acetate) to afford the target compound 16 in 98% yield. The product was a colorless liquid; 1H NMR (400 MHz, CDCl3) δ 7.30 (d, 2H, J = 7.5 Hz), 7.05 (d, 2H, J = 7.6 Hz), 3.99-3.88 (m, 4H), 2.99 (s, 1H), 2.94 (s, 1H), 1.12 (t, 6H, J = 6.9 Hz); 13C NMR ( 100 MHz, CDCl3) δ 131.7, 131.6, 131.5, 121.0, 62.3, 34.0, 32.0, 16.5; HRMS calculated value (C11H16BrO3P, [M + H]+) 307.0097, measured value 307.0093.

References

[1] Patent: US6689922, 2004, B1. Location in patent: Page column 23
[2] Chemistry - A European Journal, 2012, vol. 18, # 24, p. 7473 - 7485
[3] Synthetic Communications, 2011, vol. 41, # 2, p. 206 - 218
[4] Patent: US2013/41153, 2013, A1. Location in patent: Paragraph 0041; 0042; 0043; 0044
[5] ChemMedChem, 2010, vol. 5, # 1, p. 56 - 60

873-75-6
122-52-1
38186-51-5
Synthesis of DIETHYL 4-BROMOBENZYL PHOSPHONATE from 4-Bromobenzyl alcohol and Triethyl phosphite
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View Lastest Price from DIETHYL 4-BROMOBENZYL PHOSPHONATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DIETHYL 4-BROMOBENZYL PHOSPHONATE pictures 2020-01-01 DIETHYL 4-BROMOBENZYL PHOSPHONATE
38186-51-5
US $1.00 / KG 1KG 99% 200kg Career Henan Chemical Co

DIETHYL 4-BROMOBENZYL PHOSPHONATE Spectrum

DIETHYL 4-BROMOBENZYL PHOSPHONATE 4-BROMOBENZYL-PHOSPHONIC ACID DIETHYLESTER Diethy 4-Bromobenzyl Phosphonate Diethyl(4-Bromobenzyl)phosphonate> Phosphonic acid, P-[(4-bromophenyl)methyl]-, diethyl ester 4-Bromobenzyl diethylphosphite Diethyl P-[(4-bromophenyl)methyl]phosphonate 38186-51-5 C11H16BrO3P Piperidines ,Homopiperidines Horner-Emmons Reaction Synthetic Organic Chemistry Wittig & Horner-Emmons Reaction 1