Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>VU 0409106

VU 0409106

VU 0409106 Structure
VU 0409106 structure
CAS No.
1276617-62-9
Chemical Name:
VU 0409106
Synonyms
VU 0409106;3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide;3-Fluoro-N-(4-methylthiazol-2-yl)-5-(pyrimidin-5-yloxy)benzamide;Benzamide, 3-fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)-
CBNumber:
CB04726384
Molecular Formula:
C15H11FN4O2S
Molecular Weight:
330.34
MDL Number:
MOL File:
1276617-62-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
Request For Quotation

VU 0409106 Properties

Density 1.445±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 6.61±0.50(Predicted)
color White to off-white
FDA UNII J65UDU5WEA

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319
Precautionary statements  P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

VU 0409106 price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0033044 VU0409106 99.76% 1276617-62-9 5mg $92 2026-06-04 Buy
ChemScene CS-0033044 VU0409106 99.76% 1276617-62-9 10mg $146 2026-06-04 Buy
ChemScene CS-0033044 VU0409106 99.76% 1276617-62-9 25mg $292 2026-06-04 Buy
ChemScene CS-0033044 VU0409106 99.76% 1276617-62-9 50mg $471 2026-06-04 Buy
ChemScene CS-0033044 VU0409106 99.76% 1276617-62-9 100mg $753 2026-06-04 Buy
Product number Packaging Price Buy
CS-0033044 5mg $92 Buy
CS-0033044 10mg $146 Buy
CS-0033044 25mg $292 Buy
CS-0033044 50mg $471 Buy
CS-0033044 100mg $753 Buy

VU 0409106 Chemical Properties,Uses,Production

Uses

VU 0409106 is a novel negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5). VU0409106 also was effective in a mouse marble burying anxiety behaviour.

in vivo

VU0409106 (10 mg/kg; i.p.; once) penetrates the blood-brain barrier (BBB) and demonstrates good brain to plasma ratio that near unity[1].

Animal Model:CD-1 mice[1]
Dosage:10 mg/kg (10% Tween 80 formulation)
Administration:Intraperitoneal injection.
Result:1.19Pharmacokinetic Parameters of VU0409106 in CD-1 mice[1].
IP (10 mg/kg)
Plasma Tmax (h)0.25
Plasma Cmax (ng/mL)1450
Brain Tmax (h)0.25
Brain Cmax (ng/mL)1350
AUCplasma (ng/mLh)702
AUCbrain (ng/mLh)696
B/P ratio0.99

IC 50

mGlu5: 24 nM (IC50)

VU 0409106 Preparation Products And Raw materials

Raw materials

Preparation Products

VU 0409106 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465 sales@zehanbiopharma.com China 989 55
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
Shanghaizehan biopharma technology co., Ltd. 55
Shanghai Chaolan Chemical Technology Center 58
Shanghai Hongye Biotechnology Co. Ltd 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Lastest Price from VU 0409106 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
VU0409106 pictures 2026-07-14 VU0409106
1276617-62-9
 $222.00-575.00 99.89% 10g TargetMol Chemicals Inc.
  • VU0409106 pictures
  • VU0409106
    1276617-62-9
  • $222.00-575.00
  • 99.89%
  • TargetMol Chemicals Inc.

1276617-62-9(VU 0409106)Related Search:

VU 0357017 hydrochloride (1R,2R)-N-([S]-1-{4-[5-broMo-2-oxo-2,3-dihydro-1H-benzo(d)iMidazol-1-yl]piperidin-1-yl}propan-2-yl)-2-phenylcyclopropanecarboxaMide VU 0360172 VU 0365114 VU 0357121
VU 0364439 VU 0285683

1of2

VU 0409106 3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide Benzamide, 3-fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)- 3-Fluoro-N-(4-methylthiazol-2-yl)-5-(pyrimidin-5-yloxy)benzamide 1276617-62-9