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dBET23

dBET23 structure

CAS No.: 1957234-83-1

Chemical Name:: dBET23

Synonyms: dBET23;Methyl (6S)-4-(4-chlorophenyl)-2-[[[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]amino]carbonyl]-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2-[[[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]amino]carbonyl]-3,9-dimethyl-, methyl ester, (6S)-

CBNumber:: CB04844693

Molecular Formula:: C43H45ClN8O9S

Molecular Weight:: 885.38

MDL Number:

MOL File:: 1957234-83-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:25

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dBET23 Properties

Density	1.50±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C, sealed storage, away from moisture and light
solubility	DMSO : 170 mg/mL (192.01 mM; Need ultrasonic)
pka	10.68±0.40(Predicted)
form	Solid
color	Off-white to brown

dBET23 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-0087444	dBET23 95.83%	1957234-83-1	1mg	$422	2026-06-04	Buy
ChemScene	CS-0087444	dBET23 95.83%	1957234-83-1	5mg	$1246	2026-06-04	Buy
ChemScene	CS-0087444	dBET23 95.83%	1957234-83-1	10mg	$1950	2026-06-04	Buy
ChemScene	CS-0087444	dBET23 95.83%	1957234-83-1	25mg	$3900	2026-06-04	Buy
ChemScene	CS-0087444	dBET23 95.83%	1957234-83-1	50mg	$6283	2026-06-04	Buy

Product number	Packaging	Price	Buy
CS-0087444	1mg	$422	Buy
CS-0087444	5mg	$1246	Buy
CS-0087444	10mg	$1950	Buy
CS-0087444	25mg	$3900	Buy
CS-0087444	50mg	$6283	Buy

dBET23 Chemical Properties, Uses, Production

Uses

dBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein[1].

References

[1] Nowak RP, et al. Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 2018;14(7):706-714. DOI:10.1038/s41589-018-0055-y

dBET23 Preparation Products And Raw materials

Raw materials

Preparation Products

dBET23 Suppliers

Global Suppliers ( 5)

Supplier	Tel	Email	Country	ProdList	Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6288	58
Guangzhou Younan Technology Co., Ltd	020-82000279 18988941452	YN_research@163.com	China	2984	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	11975	58
Aladdin Scientific		tp@aladdinsci.com	United States	50089	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58

Supplier	Advantage
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Guangzhou Younan Technology Co., Ltd	58
Nanjing Shizhou Biology Technology Co.,Ltd	58
Aladdin Scientific	58
TargetMol Chemicals Inc.	58

1957234-83-1 (dBET23) Related Search:

NA dBET23 ARV-825 ZXH-3-26 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[4-[(1E)-2-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-4-yl]diazenyl]-2,6-dimethoxyphenoxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-

dBET1

1of2

dBET23 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2-[[[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]amino]carbonyl]-3,9-dimethyl-, methyl ester, (6S)- Methyl (6S)-4-(4-chlorophenyl)-2-[[[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]amino]carbonyl]-3,9-dimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetate 1957234-83-1 C43H45ClN8O9S