ChemicalBook >> CAS DataBase List >>Rodatristat)
Rodatristat)
- CAS No.
- 1673571-51-1
- Chemical Name:
- Rodatristat)
- Synonyms
- Rodatristat ethyl;Rodatristat);KAR-5585 (KAR5585;2,8-Diazaspiro[4.5]decane-3-carboxylic acid, 8-[2-amino-6-[(1R)-1-(5-chloro[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-, ethyl ester, (3S)-
- CBNumber:
- CB04844956
- Molecular Formula:
- C29H31ClF3N5O3
- Molecular Weight:
- 590.04
- MDL Number:
- MFCD32215291
- MOL File:
- 1673571-51-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:17
| storage temp. | Store at -20°C |
|---|---|
| form | Solid |
| color | White to off-white |
| FDA UNII | 507FY6OL37 |
Rodatristat) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0020885 | Rodatristat ethyl 99.82% | 1673571-51-1 | 1mg | $399 | 2026-06-04 | Buy |
| ChemScene | CS-0020885 | Rodatristat ethyl 99.82% | 1673571-51-1 | 5mg | $997 | 2026-06-04 | Buy |
| ChemScene | CS-0020885 | Rodatristat ethyl 99.82% | 1673571-51-1 | 10mg | $1571 | 2026-06-04 | Buy |
| ChemScene | CS-0020885 | Rodatristat ethyl 99.82% | 1673571-51-1 | 25mg | $2817 | 2026-06-04 | Buy |
| ChemScene | CS-0020885 | Rodatristat ethyl 99.82% | 1673571-51-1 | 50mg | $4225 | 2026-06-04 | Buy |
Rodatristat) Chemical Properties, Uses, Production
Uses
Rodatristat is used in the method for treating interstitial lung disease using a tryptophan hydroxylase inhibitor.
in vivo
Rodatristat ethyl (100 or 200 mg/kg; oral administration; once daily; for 28 days; male Sprague-Dawley rats) treatment decreases erum, gut and lung 5-HT levels in a dose-dependent manner and significantly reduces pulmonary arterial pressure, and pulmonary vessel wall thickness and occlusion in male rats with monocrotaline (MCT)[1].
| Animal Model: | Male Sprague-Dawley rats (175-200 g)[1] |
| Dosage: | 100 mg/kg or 200 mg/kg |
| Administration: | Oral administration; once daily; for 28 days |
| Result: | Decreased serum, gut and lung 5-HT levels in a dose-dependent manner and significantly reduced pulmonary arterial pressure, and pulmonary vessel wall thickness and occlusion in male rats. |
IC 50
5-HT1 Receptor; TPH1
Rodatristat) Preparation Products And Raw materials
Raw materials
Preparation Products
Rodatristat) Suppliers
Global Suppliers ( 16)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6288 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 10233 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Suzhou Haiben Pharmaceutical Co., Ltd | 19353112242 | 1816280386@qq.com | China | 8041 | 58 |
1673571-51-1 (Rodatristat)) Related Search:
KAR-5585
(KAR5585
Rodatristat)
2,8-Diazaspiro[4.5]decane-3-carboxylic acid, 8-[2-amino-6-[(1R)-1-(5-chloro[1,1'-biphenyl]-2-yl)-2,2,2-trifluoroethoxy]-4-pyrimidinyl]-, ethyl ester, (3S)-
Rodatristat ethyl
1673571-51-1
C29H31ClF3N5O3
