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LIDOFLAZINE, 98.5%

LIDOFLAZINE, 98.5% structure

CAS No.: 3416-26-0

Chemical Name:: LIDOFLAZINE, 98.5%

Synonyms: R-7904;clinium;klinium;corflazine;mcn-jr7904;lidoflazin;ordiflazine;lidoflazina;lidoflazinum;LIDOFLAZINE, 98.5%

CBNumber:: CB0501936

Molecular Formula:: C30H35F2N3O

Molecular Weight:: 491.62

MDL Number:: MFCD00057353

MOL File:: 3416-26-0.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-21 10:31:43

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LIDOFLAZINE, 98.5% Properties

Melting point	159-161°
Boiling point	632.6±55.0 °C(Predicted)
Density	1.1322 (estimate)
storage temp.	2-8°C
solubility	DMSO: ≥10mg/mL
pka	14.62±0.70(Predicted)
form	powder
color	white
InChIKey	ZBIAKUMOEKILTF-UHFFFAOYSA-N
SMILES	Cc1cccc(C)c1NC(=O)CN2CCN(CCCC(c3ccc(F)cc3)c4ccc(F)cc4)CC2
CAS DataBase Reference	3416-26-0
FDA UNII	J4ZHN3HBTE
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

PPE	dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes	Xn
Risk Statements	22
Safety Statements	36
WGK Germany	3
RTECS	TK7910000
Storage Class	11 - Combustible Solids

LIDOFLAZINE, 98.5% price More Price(13)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	L9668	Lidoflazine ≥98% (HPLC), powder	3416-26-0	5mg	$176	2026-04-30	Buy
Sigma-Aldrich	L9668	Lidoflazine ≥98% (HPLC), powder	3416-26-0	25mg	$774	2026-04-30	Buy
Usbiological	453738	Lidoflazine	3416-26-0	5mg	$502	2026-06-03	Buy
ChemScene	CS-0043285	Lidoflazine	3416-26-0	1mg	$233	2026-06-04	Buy
ChemScene	CS-0043285	Lidoflazine	3416-26-0	5mg	$582	2026-06-04	Buy

Product number	Packaging	Price	Buy
L9668	5mg	$176	Buy
L9668	25mg	$774	Buy
453738	5mg	$502	Buy
CS-0043285	1mg	$233	Buy
CS-0043285	5mg	$582	Buy

LIDOFLAZINE, 98.5% Chemical Properties, Uses, Production

Chemical Properties

WHITE TO ALMOST WHITE POWDER

Originator

Clinium,Janssen,W. Germany,1969

Uses

Coronary vasodilatator;Ca++ channel activator

Uses

Lidoflazine is a L-type Ca2+ channel antagonist.Also, it is derived from 1,1''-(4-Chlorobutylidene)bis(4-fluorobenzene) (C364775), which is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.

Definition

ChEBI: 2-[4-[4,4-bis(4-fluorophenyl)butyl]-1-piperazinyl]-N-(2,6-dimethylphenyl)acetamide is a diarylmethane.

Manufacturing Process

A mixture of 6.6 parts 1-[4,4-di-(4-fluoro-phenyl)butyl]-piperazine, 4.33 parts N-(2-chloro-acetyl)-2,6-dimethyl-aniline, 3.2 parts sodium carbonate, a few crystals of potassium iodide in 200 parts 4-methyl-2-pentanone is stirred and refluxed for 70 hours. After cooling there are added 70 parts water. The organic layer is separated, dried over potassium carbonate, filtered and evaporated. The oily residue is dissolved in 80 parts diisopropylether and the solution is filtered hot. After cooling the filtrate at 0°C. the formed solid is filtered off and recystallired from 80 parts ether, yielding 1-[4,4-di-(4-fluorophenyl)butyl]-4-[(2,6-dimethylanilino-carbonyl)-methyl]-piperazine; MP 159°C to 161°C.

brand name

Angex (Janssen); Clinium (Ortho-McNeil).

Therapeutic Function

Coronary vasodilator

Biological Activity

Lidoflazine is an antianginal calcium channel blocker th at carries a significant risk of QT interval prolongation and ventricular arrhythmia. It prolongs QT interval by blocking HERG channel. IC50 < 0.1 μM

LIDOFLAZINE, 98.5% Preparation Products And Raw materials

Raw materials

4-Bromo-2,6-dimethylaniline

Preparation Products

LIDOFLAZINE, 98.5% Suppliers

Global Suppliers ( 38)

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
Beijing HuaMeiHuLiBiological Chemical	010-56205725	waley188@sohu.com	China	12323	58
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8039	58
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9781	50
Alta Scientific Co., Ltd.	022-6537-8550 15522853686	sales@altasci.com.cn	China	4508	55
Alfa Chemistry	1-516-6625404	support@alfa-chemistry.com	United States	9170	60
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
AFINE CHEMICALS LIMITED	+86-571-85134551 +86-18958018566	info@afinechem.com	China	15030	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81139210 +86-17392587031	1059@dideu.com	China	9983	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44871	58

Supplier	Advantage
BOC Sciences	65
Beijing HuaMeiHuLiBiological Chemical	58
Shanghai TaoSu Biochemical Technology Co., Ltd.	58
Shanghai HuanChuan Industry Co.,Ltd.	50
Alta Scientific Co., Ltd.	55
Alfa Chemistry	60
TargetMol Chemicals Inc.	58
AFINE CHEMICALS LIMITED	58
Shaanxi Dideu Medichem Co. Ltd	58
Energy Chemical	58

View Latest Price from LIDOFLAZINE, 98.5% manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-14	Lidoflazine 3416-26-0		1kg	98% up by HPLC	20tons	Sinoway Industrial co., ltd.
2026-04-20	Lidoflazine 3416-26-0	$1410.00-2500.00			10g	TargetMol Chemicals Inc.
2020-05-12	Lidoflazine 3416-26-0		1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd

Lidoflazine
3416-26-0
98% up by HPLC
Sinoway Industrial co., ltd.

Lidoflazine
3416-26-0
$1410.00-2500.00
TargetMol Chemicals Inc.

Lidoflazine
3416-26-0
99.0%
Shaanxi Dideu Medichem Co. Ltd

3416-26-0 (LIDOFLAZINE, 98.5%) Related Search:

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6’-xylidide,4-(4,4-bis(p-fluorophenyl)butyl)-1-piperazineaceto-2 clinium corflazine klinium lidoflazin lidoflazina lidoflazinum mcn-jr7904 ordiflazine LIDOFLAZINE, 98.5% 4-[4,4-Bis(4-fluorophenyl)butyl]-N-(2,6-dimethylphenyl)-1-piperazineacetamide R-7904 Lidoflazine Solution, 1000ppm Lidoflazine Solution, 100ppm 1-(4,4-bis(4-fluorofenil)butil)-4-((2,6-dimetilanilinocarbonil)metil)piperaz 1-piperazineacetamide,4-(4,4-bis(4-fluorophenyl)butyl)-n-(2,6-dimethylphenyl 4-(4,4-bis(p-fluorophenyl)butyl)-1-piperazineaceto-2’,6’-xylidide Lidoflazine >=98% (HPLC), powder LIDOFLAZINE, 98.5% USP/EP/BP 3416-26-0 C30H35F2N3O