DSP-2230
- CAS No.
- 1233231-30-5
- Chemical Name:
- DSP-2230
- Synonyms
- DSP-2230;DSP-2230, 10 mM in DMSO;DSP2230; DSP 2230; DSP-2230;Inhibitor,inhibit,Na+ channels,Sodium Channel,DSP 2230,Na channels,DSP2230,DSP-2230;(2S)-2-({[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl}amino)propanamide;Propanamide, 2-[[[3-cyclobutyl-5-(3,4,5-trifluorophenoxy)-3H-imidazo[4,5-b]pyridin-2-yl]methyl]amino]-, (2S)-
- CBNumber:
- CB05417694
- Molecular Formula:
- C20H20F3N5O2
- Molecular Weight:
- 419.4
- MDL Number:
- MFCD32174279
- MOL File:
- 1233231-30-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 607.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.53±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:125.0(Max Conc. mg/mL);298.04(Max Conc. mM) |
| pka | 15.94±0.50(Predicted) |
| form | Solid |
| color | White to off-white |
| InChIKey | HHXCJIMPEJSJTG-JTQLQIEISA-N |
| SMILES | C(N)(=O)[C@@H](NCC1=NC2=CC=C(OC3=CC(F)=C(F)C(F)=C3)N=C2N1C1CCC1)C |
| FDA UNII | LSY2D22FBK |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 |
DSP-2230 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | IZB23130 | DSP-2230 | 1233231-30-5 | 25mg | $982.75 | 2026-06-04 | Buy |
| Biosynth | IZB23130 | DSP-2230 | 1233231-30-5 | 50mg | $1367.5 | 2026-06-04 | Buy |
| Biosynth | IZB23130 | DSP-2230 | 1233231-30-5 | 100mg | $2188 | 2026-06-04 | Buy |
| ChemScene | CS-0089255 | DSP-2230 98.33% | 1233231-30-5 | 5mg | $87 | 2026-06-04 | Buy |
| ChemScene | CS-0089255 | DSP-2230 98.33% | 1233231-30-5 | 10mg | $141 | 2026-06-04 | Buy |
DSP-2230 Chemical Properties, Uses, Production
Uses
DSP-2230 is a selective Nav1.7/Nav1.8 blocker, can be used to improve neuropathic pain[1][2][3].
IC 50
Nav1.7; Nav1.8
References
[1] Bagal SK, et al. Voltage gated sodium channels as drug discovery targets. Channels (Austin). 2015;9(6):360-6. DOI:10.1080/19336950.2015.1079674
[2] Sara Sabina Hadida-Ruah, et al. Sulfonamides as modulators of sodium channels.
[3] Matthew Alsaloum, et al. Status of peripheral sodium channel blockers for non-addictive pain treatment. Nat Rev Neurol. 2020 Dec;16(12):689-705. DOI:10.1038/s41582-020-00415-2
DSP-2230 Preparation Products And Raw materials
Raw materials
Preparation Products
DSP-2230 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fujian boshi pharmaceutical technology co. LTD | 0595-22008920; 18120708884 | 393612455@qq.com | China | 257 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4858 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9718 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Shanghai Dongyang Biotechnology Co., Ltd. | 0512-13601744364 13601744364 | chemsharker@126.com | China | 1162 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
