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(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium structure

CAS No.: 301224-40-8

Chemical Name:: (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium

Synonyms: HOVEYDA-GRUBBS;HOVEYDA-GRUBBS CATALYST;Hoveyda-Grubbs II;Hoveyda-Grubbs 2nd;Hoveyda-Grubbs Catalyst 2nd;Hoveyda-Grubbs Catalyst 2nd Generation;Hoveyda-Grubbs G2;Dichloro(1,3-diMesityl-2-iMidazolidinylidene)(2-isopropoxybenzylidene)rutheniuM;[1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(2-isopropoxyphenyl)methylene]ruthenium;(1,3-DiMesityliMidazolidin-2-ylidene)(2-isopropoxybenzylidene)rutheniuM(VI) chloride

CBNumber:: CB0667713

Molecular Formula:: C31H37Cl2N2ORu

Molecular Weight:: 625.62

MDL Number:: MFCD03701614

MOL File:: 301224-40-8.mol

MSDS File:: SDS

Last updated:2026-09-12 18:48:27

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(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium Properties

Melting point	216-220 °C(lit.)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
form	Solid
color	Green to Very Dark Green
Stability	Hygroscopic
InChIKey	ZRPFJAPZDXQHSM-UHFFFAOYSA-L
SMILES	[Cl-][Ru+6]1(=[C-2]2N(C3C(=CC(C)=CC=3C)C)CCN2C2C(=CC(C)=CC=2C)C)(=[C-2]C2=CC=CC=C2O1C(C)C)[Cl-]
CAS DataBase Reference	301224-40-8
FDA UNII	YFT5355ZK7
EPA Substance Registry System	Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-.kappa.O)phenyl]methylene-.kappa.C]-, (SP-5-41)- (301224-40-8)
UNSPSC Code	12161600
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS05
Signal word	Danger
Hazard statements	H314-H227
Precautionary statements	P501-P210-P264-P280-P370+P378-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P403+P235-P405
PPE	Eyeshields, Gloves, type N95 (US)
WGK Germany	3
TSCA	TSCA listed
Storage Class	11 - Combustible Solids

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium price More Price(51)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	569755	Hoveyda-Grubbs Catalyst 2nd Generation 97%	301224-40-8	2g	$293	2026-04-30	Buy
Sigma-Aldrich	569755	Hoveyda-Grubbs Catalyst 2nd Generation 97%	301224-40-8	25g	$1560	2026-04-30	Buy
TRC	TRC-B588655-500MG	[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] Dichloro(o-isopropoxyphenylmethylene)ruthenium	301224-40-8	500mg	$396	2026-06-03	Buy
TRC	TRC-B588655-100MG	[1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene] Dichloro(o-isopropoxyphenylmethylene)ruthenium	301224-40-8	100mg	$97	2026-06-03	Buy
AK Scientific	W5252	(1,3-Dimesitylimidazolidin-2-ylidene)(2-isopropoxybenzylidene)ruthenium(VI) chloride 98%	301224-40-8	100mg	$21	2026-06-04	Buy

Product number	Packaging	Price	Buy
569755	2g	$293	Buy
569755	25g	$1560	Buy
TRC-B588655-500MG	500mg	$396	Buy
TRC-B588655-100MG	100mg	$97	Buy
W5252	100mg	$21	Buy

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium Chemical Properties, Uses, Production

Chemical Properties

Bright green crystalline powder

Uses

It′s a phosphine free version of Grubbs 2^nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.
It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.

reaction suitability

core: ruthenium
reagent type: catalyst
reaction type: Ring-Opening Polymerization

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium synthesis

Synthesis of (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium from Grubbs catalyst 2nd generation and 1,2-Bis(diphenylphosphino)ethane

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium Preparation Products And Raw materials

Raw materials

1,2-Bis(diphenylphosphino)ethane Benzene, 1-ethenyl-2-(1-Methylethoxy)- Grubbs catalyst 2nd generation

Preparation Products

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium Suppliers

Global Suppliers ( 192)

Supplier	Tel	Email	Country	ProdList	Advantage
xinxiang runyu material co.,Ltd	03737759608 15690792173	sales@runvmat.com	China	300	58
Shanghai CoachChem Co., Ltd.	+86-21-67299971；+86-21-67290723 18117322963	marketing@coachchem.com	China	96	62
Shanghai Tube Pharmaceutical Co., Ltd.	021-54338626 18017892860	sales@tubepharm.com	China	2709	58
ChemicalRIM Co., Ltd	15184345951	chemicalRIM@gmail.com	China	46	58
Wuhan Huahan Dingcheng New Material Technology Co., Ltd	18963961905	huahandingcheng@sina.com	China	482	58
Sinocompound Catalysts Co., Ltd.	0512-67216630 67216634	sales@sinocompound.com	China	252	64
Wuhan phosphine biologic Pharmaceutical Co., LTD	15102702255	35729423@qq.com	China	247	58
Shanghai Pulikang Chemical Technology Co., Ltd	13105330140 13105330140	icyan@126.com	China	266	58
Shaanxi Rock New Materials Co., Ltd.	0917-15619726767 18691786767	gongyinchuan@bjrock.com	China	92	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62

Supplier	Advantage
xinxiang runyu material co.,Ltd	58
Shanghai CoachChem Co., Ltd.	62
Shanghai Tube Pharmaceutical Co., Ltd.	58
ChemicalRIM Co., Ltd	58
Wuhan Huahan Dingcheng New Material Technology Co., Ltd	58
Sinocompound Catalysts Co., Ltd.	64
Wuhan phosphine biologic Pharmaceutical Co., LTD	58
Shanghai Pulikang Chemical Technology Co., Ltd	58
Shaanxi Rock New Materials Co., Ltd.	58
Meryer (Shanghai) Chemical Technology Co., Ltd.	62

View Latest Price from (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-25	Hoveyda-Grubbs II 301224-40-8	$2.00-5.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-12-23	Hoveyda-Grubbs catalyst 301224-40-8		1g	98%	100g	XINXIANG RUNYU MATERIAL CO., LTD.
2019-07-06	(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM 301224-40-8	$1.00	1KG	98%	1ton	Career Henan Chemical Co

Hoveyda-Grubbs II
301224-40-8
$2.00-5.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Hoveyda-Grubbs catalyst
301224-40-8
98%
XINXIANG RUNYU MATERIAL CO., LTD.

(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM
301224-40-8
$1.00
98%
Career Henan Chemical Co

(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium Spectrum

(1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM(301224-40-8)¹HNMR

301224-40-8 ((1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium) Related Search:

1,3-Bis(2,4,6-trimethylphenyl)-imidazolidinium-chloride Bis(triphenylphosphine)palladium(II) chloride Tetrakis(triphenylphosphine)palladium Dicyclopentadiene [1,1'-Bis(diphenylphosphino)ferrocene]dichloropalladium(II)

1,1'-Bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethane complex 1,1'-Bis (di-t-butylphosphino)ferrocene palladium dichloride, Ruthenium(III) chloride hydrate Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](benzylidene)bis(3-bromopyridine)ruthenium(II) Benzylidene-bis(tricyclohexylphosphine)dichlororuthenium

Grubbs catalyst 2nd generation Dichloro-[1,3-bis(diisopropylphenyl)imidazolylidene]-(3-chloropyridyl)palladium(II) Dichloro(o-isopropoxyphenylmethylene)(tricyclohexylphosphine)ruthenium(II) (1,5-Cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) hexafluorophosphate (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium

Ruthenium 1,3-Bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene[2-(i-propoxy)-5-(N,N-dimethylaminosulfonyl)phenyl]methyleneruthenium(II)dichloride Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro-[[2-isopropoxy-5-(N-resin-linked aminosulfonyl)phenyl]methylene]

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RUTHENIUM,[1,3-BIS(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE]DICHLORO[[2-(1-METHYLETHOXY)PHENYL]METHYLENE] [1,3-Bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(2-isopropoxyphenylmethylene)ruthenium Hoveyda-Grubbs Catalyst 2nd Generation,(1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium (1,3-Bis-(2,4,6-triMethylphenyl)-2-iMidazolidinylidene)dichloro (o-isopropylphenylMethylene)rutheniuM NH22260 Hoveyda-Grubbs Catalyst 2nd Generation,97% Hoveyda-Grubbs Catalyst 2nd Generation 97% eneration Hoveyda-g rubbs CataL yst 2nd g Hoveyda-Grubbs Catalyst(TM) 2nd Generation Hoveyda-Grubbs CataL yst 2nd Generation (1,3-BIS-(2,4,6-TRIMETHYLPHENYL)-2-IMIDAZOLIDINYLIDENE)DICHLORO(O-ISOPROPOXYPHENYLMETHYLENE)RUTHENIUM ISO 9001：2015 REACH [1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(2-isopropoxybenzylidene)ruthenium(II) Hoveyda-Grubbs Catalyst 3nd Generation Dichloro(1,3-Dimesityl-2-imidazolidinylidene)(o-isopropoxyphenylmethylene)ruthenium Hoveyda-Grubbs Catalyst^? M720 Hoveyda-Grubbs Catalyst?M720 [1,3-bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene]-dichloro-[(2-isopropoxyphenyl)methylene]ruthenium Hoveyda-Grubbs Catalyst 2nd Gen (1,3-DiMesityliMidazolidin-2-ylidene)(2-isopropoxybenzylidene)rutheniuM(VI) chloride Dichloro(1,3-diMesityl-2-iMidazolidinylidene)(2-isopropoxybenzylidene)rutheniuM Hoveyda-Grubbs Catalyst 2nd Hoveyda-Grubbs G2 Hoveyda-Grubbs II HOVEYDA-GRUBBS CATALYST Hoveyda-Grubbs Catalyst 2nd Generation Hoveyda-Grubbs 2nd HOVEYDA-GRUBBS (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium 301224-40-8 C31H38Cl2N2ORu Catalysis and Inorganic Chemistry Metathesis Catalysts Ru