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Ticlopidine hydrochloride

Ticlopidine hydrochloride Structure
Ticlopidine hydrochloride structure
CAS No.
53885-35-1
Chemical Name:
Ticlopidine hydrochloride
Synonyms
TICLOPIDINE HCL;Soper;tiklid;53-32c;4-c-32;ticlid;Tiklyd;ticlodix;Iparazin;panaldine
CBNumber:
CB0674371
Molecular Formula:
C14H14ClNS.ClH
Molecular Weight:
300.25
MDL Number:
MFCD00079606
MOL File:
53885-35-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-17 09:03:53
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Ticlopidine hydrochloride Properties

Melting point 205°C
Density 1.37 g/cm3
storage temp. Inert atmosphere,Room Temperature
solubility Sparingly soluble in water and in anhydrous ethanol, very slightly soluble in ethyl acetate.
pka 7.64(at 25℃)
form Solid
color White
Water Solubility Soluble to 100 mM in water and to 100 mM in DMSO.
λmax 295nm(H2O)(lit.)
Merck 14,9421
Major Application forensics and toxicology
pharmaceutical (small molecule)
veterinary
InChI InChI=1S/C14H14ClNS.ClH/c15-13-4-2-1-3-11(13)9-16-7-5-14-12(10-16)6-8-17-14;/h1-4,6,8H,5,7,9-10H2;1H
InChIKey MTKNGOHFNXIVOS-UHFFFAOYSA-N
SMILES C12C=CSC=1CCN(CC1C=CC=CC=1Cl)C2.Cl
CAS DataBase Reference 53885-35-1(CAS DataBase Reference)
FDA UNII A1L4914FMF
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  36-37/39-26
WGK Germany  3
RTECS  XJ9089100
HS Code  2934990002
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Toxicity LD50 in mice (mg/kg/24 hrs): 55 i.v.; >300 orally (Castaigne)
NFPA 704
0
3 0

Ticlopidine hydrochloride price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T6654 Ticlopidine hydrochloride analytical standard, for drug analysis 53885-35-1 1g $42.1 2026-04-30 Buy
Sigma-Aldrich T1423000 Ticlopidine hydrochloride European Pharmacopoeia (EP) Reference Standard 53885-35-1 50 mg $127 2026-04-30 Buy
Sigma-Aldrich PHR3367 Ticlopidine hydrochloride certified reference material, pharmaceutical secondary standard 53885-35-1 300MG $242 2026-04-30 Buy
Sigma-Aldrich 1667144 Ticlopidine hydrochloride United States Pharmacopeia (USP) Reference Standard 53885-35-1 150mg $455 2026-04-30 Buy
TCI Chemical T3110 Ticlopidine Hydrochloride >98.0%(HPLC)(N) 53885-35-1 5g $55 2026-04-30 Buy
Product number Packaging Price Buy
T6654 1g $42.1 Buy
T1423000 50 mg $127 Buy
PHR3367 300MG $242 Buy
1667144 150mg $455 Buy
T3110 5g $55 Buy

Ticlopidine hydrochloride Chemical Properties, Uses, Production

Chemical Properties

White Solid

Originator

Ticlid,Millot,France,1978

Uses

Ticlopidine hydrochloride is a selective P2Y12 receptor antagonist. It inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo.

Uses

An antithrombotic. a platelet aggregation inhibitor

Uses

mucolytic, antibacterial, surface active agent

Manufacturing Process

A solution of thieno[3,2-c]pyridine (13.5 g; 0.1 mol) and 2-chlorobenzyl chloride (17.7 g) in acetonitrile (150 ml) is boiled during 4 hours. After evaporation of the solvent, the solid residue consists of 5-(2- chlorobenzyl)-thieno[3,2-c]pyridinium chloride which melts at 166°C (derivative n° 30). This compound is taken up into a solution comprising ethanol (300 ml) and water (100 ml). Sodium borohydride (NaBH4)(20 g) is added portionwise to the solution maintained at room temperature. The reaction medium is maintained under constant stirring during 12 hours and is then evaporated. The residue is taken up into water and made acidic with concentrated hydrochloric acid to destroy the excess reducing agent. The mixture is then made alkaline with ammonia and extracted with ether. The ether solution is washed with water, dried and evaporated. The oily residue is dissolved in isopropanol (50 ml) and hydrochloric acid in ethanol solution is then added thereto.
After filtration and recrystallization from ethanol, there are obtained 5-(2- chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride crystals (yield: 60%) having a melting point (Koefler block) of 190°C.

Therapeutic Function

Platelet aggregation inhibitor

Biological Activity

Selective P2Y 12 receptor antagonist. Inhibits ADP-induced platelet aggregation and displays antithrombotic activity following oral administration in vivo .

References

[1] Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 8, p. 1676 - 1678
[2] Patent: CN105461735, 2016, A. Location in patent: Paragraph 0020; 0021
[3] Patent: CN105541862, 2016, A. Location in patent: Paragraph 0015; 0019

Ticlopidine hydrochloride Preparation Products And Raw materials

Raw materials

2-(2-Chlorophenyl)acetonitrile Sodium borohydride Thieno[3,2-d]pyrimidine-7-methanamine (9CI) 1H-Pyrrolo[3,2-c]pyridine, 6-methyl- Carbon
4,5,6,7-Tetrahydrothieno[3,2-c]pyridine 1,3-Dioxolane Diisopropyl ether N-(2-Chlorobenzyl)-2-(2-thienyl)ethylamine hydrochloride 2-Chlorobenzyl chloride

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Preparation Products

Ticlopidine

Ticlopidine hydrochloride Suppliers

Global Suppliers ( 338)
Supplier Tel Email Country ProdList Advantage
Suzhou Philip Johnson Pharmaceutical Co., Ltd -- wangchunhua@homesunpharm.com China 57 50
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Supplier Advantage
Suzhou Philip Johnson Pharmaceutical Co., Ltd 50
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chembest Research Laboratories Limited 61
TCI (Shanghai) Development Co., Ltd. 81
Beijing HwrkChemical Technology Co., Ltd 55
Pure Chemistry Scientific Inc. 62
Adamas Reagent, Ltd. 59
LGM Pharma 70
Chemsky（shanghai）International Co.,Ltd. 50

View Latest Price from Ticlopidine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ticlopidine hydrochloride pictures 2026-09-18 Ticlopidine hydrochloride
53885-35-1
 1KG 98%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
Ticlopidine hydrochloride pictures 2026-09-02 Ticlopidine hydrochloride
53885-35-1
 $6.00 1KG 99% Henan Fengda Chemical Co., Ltd
Ticlopidine hydrochloride USP/EP/BP pictures 2026-08-20 Ticlopidine hydrochloride USP/EP/BP
53885-35-1
 $1.10 1g 99.9% 100 Tons min Dideu Industries Group Limited

Ticlopidine hydrochloride Spectrum

Ticlopidine hydrochloride(53885-35-1)1HNMR

53885-35-1 (Ticlopidine hydrochloride) Related Search:

Pizotifen Diphenhydramine Hydrochloride Pyridine Cephaloridine Hydrochlorothiazide
Topotecan hydrochloride 1-AdaMantanethylaMine TICLOPIDINE IMPURITY F Ticlopidine IMpurity G Benzenemethanamine, 2-chloro-N-(phenylmethylene)-, (E)- (9CI)
4-Oxo Ticlopidine Ticlopidine IMpurity J 2-Chlorobenzylamine Ticlopidine IMpurity D 6.7-dihydrothieno[3.2.c]pyridin-4(5H)-one
Ticlopidine IMpurity E thieno[3,2-c]pyridine N-(2-Chlorobenzyl)-2-(2-thienyl)ethylamine hydrochloride

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4-c-32 53-32c panaldine ticlid ticlodix ticlodone 5-(o-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridinium chloride ticlodipine hydrochloride Anagregal, Caudaline, Panaldine, Ticlid, Ticlodix, 5-[(2-Chlorophenyl)-methyl]-4,5,6,7-tetrahydrothienol[3,2-C]pyridine 5-(o-Chlorbenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridiniumchlorid tiklid Tiklyd Ticlopidine Hydrochloride API Thieno[3,2-c]pyridine,5-[(2-chlorophenyl)Methyl]-4,5,6,7-tetrahydro-, hydrochloride (1:1) 5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydro-thieno[3,2-c]pyridine, hydrochloride (1:1) Ticlopidine hydrochloride, >=99% Ticlopidine hydrocahloride Dilpender Iparazin Soper 5-[(2-Chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridinehydrochloride Ticlopidine Hydrochloride (150 mg) 5-[(2-chlorophenyl)Methyl]-4H,5H,6H,7H-thieno[3,2-c]pyridine 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine hydrochloride 5-[O-CHLOROBENZYL]-4,5,6,7-TETRAHYDRO-THIENO[3,2-C]PYRIDINE HYDROCHLORIDE 5-[O-CHLOROBENZYL]-4,5,6,7-TETRAHYDROTHIENOL[3,2-C]PYRIDINE HYDROCHLORIDE TICLOPIDINE HYDROCHLORIDE 2-c)pyridine,4,5,6,7-tetrahydro-5-(o-chlorobenzyl)-thieno(hydrochloride 2-c)pyridine,5-((2-chlorophenyl)methyl)-4,5,6,7-tetrahydro-thieno(hydroc Ticlopidine HCl ( EDMF /COS) Ticlopidine Hydrochloride (Cos) Bp2007/Ep6 Ticlodipine HCl Ticlopidine hydrochloride USP/EP/BP 5 - (2-Chlorobenzyl) - 4,5,6,7-tetrahydropheno [3,2-c] pyridine hydrochloride Ticlopidine Deuterated Ticlopidine HydrochlorideQ: What is Ticlopidine Hydrochloride Q: What is the CAS Number of Ticlopidine Hydrochloride Q: What is the storage condition of Ticlopidine Hydrochloride Q: What are the applications of Ticlopidine Hydrochloride Ticlopidine Hydrochloride (1667144) Ticlopidine Hydrochloride, ≥ 98.0% Ticlopidine hydrochloride in methanol Ticlopidine hydrochloride, 10 mM in DMSO Ticlopidine HCl - Bio-X ? TICLOPIDINE HCL 53885-35-1 C14H15Cl2NS C14H14CINSHCI C14H14ClNSHCl TF - TO Alphabetic Analytical Chromatography Product Catalog Analytical Standards API THONZIDE Active Pharmaceutical Ingredients Heterocyclic Compounds Bases & Related Reagents Heterocycles Intermediates & Fine Chemicals Nucleotides