(-)-[3R,4s]-chromanol 293b
![(-)-[3R,4s]-chromanol 293b Structure](CAS/GIF/163163-24-4.gif)
- CAS No.
- 163163-24-4
- Chemical Name:
- (-)-[3R,4s]-chromanol 293b
- Synonyms
- (-)-[3R;(-)-Chromanol 293B;4S]-Chromanol 293B;(-)-[3R,4S]-Chromano;(?)-[3R,4S]-Chromanol 293B;(-)-[3R,4s]-chromanol 293b;Chromanol 293B [3R,4S]-(-)-;( ) Chromanol 293B,()Chromanol 293B;N-((3R,4S)-6-Cyano-3-hydroxy-2,2-dimethylchroman-4-yl)-N-methylethanesulfonamide;N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methylethanesulfonamide
- CBNumber:
- CB0677882
- Molecular Formula:
- C15H20N2O4S
- Molecular Weight:
- 324.4
- MDL Number:
- MFCD06798368
- MOL File:
- 163163-24-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
(-)-[3R,4s]-chromanol 293b price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 254402 | (-)-[3R,4S]-Chromanol 293B Asreported | 163163-24-4 | 10mg | $480 | 2026-06-03 | Buy |
| Usbiological | 254402 | (-)-[3R,4S]-Chromanol 293B Asreported | 163163-24-4 | 50mg | $1409 | 2026-06-03 | Buy |
| ChemScene | CS-0032830 | (-)-Chromanol 293B | 163163-24-4 | 10mg | $652 | 2026-06-04 | Buy |
| ApexBio Technology | B6753 | (-)-[3R,4S]-Chromanol 293B | 163163-24-4 | 10mg | $515 | 2026-05-06 | Buy |
| ApexBio Technology | B6753 | (-)-[3R,4S]-Chromanol 293B | 163163-24-4 | 50mg | $1708 | 2026-05-06 | Buy |
(-)-[3R,4s]-chromanol 293b Chemical Properties,Uses,Production
Uses
(-)-Chromanol 293B is a potent and selective inhibitor of the slow component of delayed rectifier K+ current (IKs). (-)-Chromanol 293B can be used for the research of antiarrhythmic[1].
Definition
ChEBI: Chromanol 293B is a 1-benzopyran.
Biological Activity
Enantiomer that selectively inhibits the slow component of delayed rectifier K + current (I Ks ). Block is use-dependent and 7-fold more potent than the (+)-(3S,4R) enantiomer (IC 50 values are 1.36 and 9.6 μ M respectively). Has negligible inhibitory action at hERG channels (IC 50 > 30 μ M).
storage
Room temperature
References
[1] Yang IC, et al. Stereoselective interactions of the enantiomers of chromanol 293B with human voltage-gated potassium channels. J Pharmacol Exp Ther. 2000;294(3):955-962. PMID:10945846
(-)-[3R,4s]-chromanol 293b Preparation Products And Raw materials
Raw materials
Preparation Products
(-)-[3R,4s]-chromanol 293b Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8435 | 60 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8137 | 58 |
| Shanghai Universal Biotech Co.,Ltd | 15921930842 15921930842 | yh-wang@univ-bio.com | China | 25030 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5987 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50089 | 58 |
