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2-Amino-3,5-dibromobenzaldehyde

2-Amino-3,5-dibromobenzaldehyde Structure
2-Amino-3,5-dibromobenzaldehyde structure
CAS No.
50910-55-9
Chemical Name:
2-Amino-3,5-dibromobenzaldehyde
Synonyms
3,5-DIBROMOANTHRALDEHYDE;Ambroxol EP Impurity E;BroMhexine EP IMpurity B;2-AMino-3;Ambroxol-5;5-dibroMobenzaldehyde;BroMhexine IMpurity B;Bromhexine Impurity Ⅱ;3,5-DIBROMANTHRANILALDEHYD;3,5-DIBROMOANTHRANILALDEHYDE
CBNumber:
CB0689243
Molecular Formula:
C7H5Br2NO
Molecular Weight:
278.93
MDL Number:
MFCD00671100
MOL File:
50910-55-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 22:50:57
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2-Amino-3,5-dibromobenzaldehyde Properties

Melting point 130-135 °C (lit.)
Boiling point 319.9±42.0 °C(Predicted)
Density 2.0123 (rough estimate)
refractive index 1.6400 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka -2.29±0.10(Predicted)
color Yellow
Sensitive Air Sensitive
InChI InChI=1S/C7H5Br2NO/c8-5-1-4(3-11)7(10)6(9)2-5/h1-3H,10H2
InChIKey RCPAZWISSAVDEA-UHFFFAOYSA-N
SMILES C(=O)C1=CC(Br)=CC(Br)=C1N
CAS DataBase Reference 50910-55-9(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38-36
Safety Statements  37/39-26-36
WGK Germany  3
HS Code  29223990
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
REACH Registrations Active
NFPA 704
1
2 0

2-Amino-3,5-dibromobenzaldehyde price More Price(66)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 463469 2-Amino-3,5-dibromobenzaldehyde 97% 50910-55-9 5g $90 2026-04-30 Buy
Sigma-Aldrich 463469 2-Amino-3,5-dibromobenzaldehyde 97% 50910-55-9 25g $150 2023-06-20 Buy
TCI Chemical D2625 3,5-Dibromoanthranilaldehyde >98.0%(GC) 50910-55-9 5g $18 2026-04-30 Buy
TCI Chemical D2625 3,5-Dibromoanthranilaldehyde >98.0%(GC) 50910-55-9 25g $36 2026-04-30 Buy
Usbiological 258583 2-Amino-3,5-Dibromobenzaldehyde Asreported 50910-55-9 5g $389 2026-06-03 Buy
Product number Packaging Price Buy
463469 5g $90 Buy
463469 25g $150 Buy
D2625 5g $18 Buy
D2625 25g $36 Buy
258583 5g $389 Buy

2-Amino-3,5-dibromobenzaldehyde Chemical Properties, Uses, Production

Chemical Properties

Yellow crystalline powder

Uses

2-Amino-3,5-dibromobenzaldehyde is a reagent used in the preparation of Ambroxol and Bromhexine (B678600) metabolites.

Uses

2-Amino-3,5-dibromobenzaldehyde may be employed in the preparation of tetradentate Schiff base ligands, via condensation with aliphatic diamines. These ligands forms nickel (II) and oxovanadium(IV) complexes.

General Description

2-Amino-3,5-dibromobenzaldehyde has been identified as one of the oxidation product of bromhexine by controlled potential electrolysis followed by HPLC-UV and GC-MS. It participates in the Friedlnder condensation of C-βglycosylic ketones to form 2-substituted quinoline derivatives.

Synthesis

2-Aminobenzaldehyde

529-23-7

2-Amino-3,5-dibromobenzaldehyde

50910-55-9

(1) Mix ethanol, water and o-aminobenzaldehyde with stirring at a molar ratio of 4:1:0.2. Elevate the temperature until the solid o-aminobenzaldehyde was completely dissolved; (2) add reduced iron powder, add 3 to 5 drops of hydrochloric acid, stir thoroughly, continue to elevate the temperature until the reaction system reached the reflux temperature, keep stirring the reaction, and monitor the progress of the reaction using high-performance liquid chromatography (HPLC); (3) after completion of the reaction, the reaction solution was filtered, and a mixture of bromine, potassium bromide, and water was added slowly to the filtrate by dropwise addition, and after completion of the dropwise addition, the Maintain the temperature and continue to stir the reaction; (4) add an excess of saturated sodium bicarbonate solution to the reaction mixture, stir well, precipitate a solid, and filter to obtain 2-amino-3,5-dibromobenzaldehyde. In this embodiment, the molar ratio of o-aminobenzaldehyde, bromine and potassium bromide was 1:1.93:9.5. The yield of 2-amino-3,5-dibromobenzaldehyde was 91.1% and the purity was 99.4%.

References

[1] Patent: CN107488121, 2017, A. Location in patent: Paragraph 0017; 0018; 0019; 0020-0023; 0025-0030; 0032-0037
[2] Patent: CN107488124, 2017, A. Location in patent: Paragraph 0018; 0019; 0020; 0021; 0022; 0023; 0024-0038
[3] Australian Journal of Chemistry, 1980, vol. 33, # 1, p. 91 - 99
[4] Patent: CN107488126, 2017, A. Location in patent: Paragraph 0018-0024; 0027-0031; 0034-0038
[5] Chemische Berichte, 1901, vol. 34, p. 1338

2-Amino-3,5-dibromobenzaldehyde Preparation Products And Raw materials

Raw materials

Benzaldehyde, 3,5-dibromo-2-nitro- Bromhexine hydrochloride 2-Aminobenzaldehyde Water 2-(2-Nitrophenyl)-1,3-dioxolane
2-Amino-3,5-dibromobenzyl alcohol Potassium bromide 2-(1,3-Dioxolan-2-yl)aniline Ethanol 2-Nitrobenzaldehyde

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Preparation Products

Ethyl 6,8-dibromo-2-oxo-1,2-dihydro-3-quinolinecarboxylate Ambroxol hydrochloride

2-Amino-3,5-dibromobenzaldehyde Suppliers

Global Suppliers ( 638)
Supplier Tel Email Country ProdList Advantage
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Shanghai jing Hao pharmaceutical technology co., LTD 021-68900963 15618693615 sales@jinghaopharma.com China 300 58
Shanghai Witofly Chemical Co. ,Ltd. 02150630626 17717886015 sales@witofly.com China 1864 55
Jinan Dexinjia Bio&Tech Co., Ltd 0531-82375880 15098789112 3845379039@qq.com China 1458 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 0513-82104991 18862997351 sales11@btcpharm.com China 859 58
Jinan Haifang Biotechnology Co., Ltd. 18560075918 2339185092@qq.com China 9 58
SHANGHAI INSPO CHEMICAL CO.,LTD 18917565227 inspo@inspochem.com China 631 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
INTATRADE GmbH +49 3493/605464 sales@intatrade.de Germany 3563 66
Supplier Advantage
Shanghai Qiao Chemical Science Co., Ltd 65
Shanghai jing Hao pharmaceutical technology co., LTD 58
Shanghai Witofly Chemical Co. ,Ltd. 55
Jinan Dexinjia Bio&Tech Co., Ltd 58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd. 58
Jinan Haifang Biotechnology Co., Ltd. 58
SHANGHAI INSPO CHEMICAL CO.,LTD 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
INTATRADE GmbH 66

View Latest Price from 2-Amino-3,5-dibromobenzaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Amino-3,5-dibromobenzaldehyde pictures 2026-09-15 2-Amino-3,5-dibromobenzaldehyde
50910-55-9
 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
2-Amino-3,5-dibromobenzaldehyde pictures 2026-08-07 2-Amino-3,5-dibromobenzaldehyde
50910-55-9
 $1.00-4.00 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
2-Amino-3,5-dibromobenzaldehyde pictures 2026-06-30 2-Amino-3,5-dibromobenzaldehyde
50910-55-9
 1kg 98% 1000kg Shaanxi Dideu New Materials Co. Ltd

2-Amino-3,5-dibromobenzaldehyde Spectrum

2-Amino-3,5-dibromobenzaldehyde(50910-55-9)MS2-Amino-3,5-dibromobenzaldehyde(50910-55-9)1HNMR2-Amino-3,5-dibromobenzaldehyde(50910-55-9)13CNMR2-Amino-3,5-dibromobenzaldehyde(50910-55-9)IR12-Amino-3,5-dibromobenzaldehyde(50910-55-9)IR2

50910-55-9 (2-Amino-3,5-dibromobenzaldehyde) Related Search:

3-Aminophenol 2-Nitrobenzaldehyde 3-(Trifluoromethyl)benzaldehyde 4-Hydroxybenzaldehyde Benzaldehyde
6-Aminocaproic acid 2,3-Dibromopropionic acid p-Anisaldehyde 2-Aminobenzaldehyde 4-Dimethylaminobenzaldehyde
Bromhexine Hydrochloride Impurity I Tris(hydroxymethyl)aminomethane Glycine Aminoethoxyvinyl glycine hydrochloride 3-(Methoxymethoxy)benzaldehyde
2-Amino-3,5-dibromobenzyl alcohol 1-Amino-2,4-dibromoanthraquinone Vat Blue 4B

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3,5-DIBROMOANTHRALDEHYDE 3,5-DIBROMOANTHRANILALDEHYDE 3,5-DIBROMANTHRANILALDEHYD 2-AMINO-3,5-DIBROMOBENZALDEHYDE 3,5-Dibromo-2-aminobenzaldehyde 2-AMINO-3,5-DIBROMOBENZALDEHYDE 98+% 2-Amino-3,5-Bromo Benzaldehyde 2-AMINO-3,5-DIBROMOBENZALDEHYDE=3,5-DIBROMOANTHRANILALDEHYDE Benzaldehyde, 2-amino-3,5-dibromo- 2-Amino-3,5-dibromobenzaldehyde,97% 3,5-Dibromobenzaldehyde-2-Amino 3,5-Dibromo-O-Aminobenzaldehyde Bromhexine Impurity 2（EP Impurity B） Ambroxol-5 Ambroxol Impurity 2（Ambroxol EP Impurity E） 2-AMino-3 5-dibroMobenzaldehyde 2-AMino-3,5-dibroMobenzaldehyde, 97% 5GR BroMhexine IMpurity B 3,5-DibroMoanthranilaldehyde, 98.0%(GC) Ambroxol impurity EP impurity E 2-amio-3,5-dibromobenzaldehyde Bromhexine Impurity Ⅱ Dibromoanthranilaldehyde Dibromoanthranilaldehyde Ambroxol EP Impurity E (Bromhexine EP Impurity B) 3,5-Dibromoanthranilaldehyde> Ambroxol hydrochloride Imp. E (Bromhexine EP Impurity B) 2-AMINO-3,5-DIBROMO BENZALDEHYDE (ADBA) 2-Amino-3,5-dibrombenzaldehyd Bromhexine EP Impurity B (Ambroxol EP Impurity E) Bromhexine Impurity 2（Bromhexine EP Impurity B） 2-Amino-3,5-dibromobenzaldehyde (Ambroxol Impurity) Ambroxol EP Impurity EQ: What is Ambroxol EP Impurity E Q: What is the CAS Number of Ambroxol EP Impurity E Q: What is the storage condition of Ambroxol EP Impurity E Q: What are the applications of Ambroxol EP Impurity E 3-methyl-1-(2,6,6-trimethylcyclohex-1-en-1-yl)penta-1,4 Ambroxol Hydrochloride EP Impurity E Bromhexine Hydrochloride EP Impurity B 3,5-Dibromo-2-aminobenChemicalbookzaldehyde 2-Amino-3,5-dirbomobenzaldehyde Ambroxol EP Impurity E/Bromhexine hydrochloride EP impurity B 2-Amino-3,5-dibomobenzaldehyde (ADBA) 2 mino-3,5-dibromobenzaldehyde BroMhexine IMpurity B, 10 mM in DMSO Ambroxol Hydrochloride Impurity 2 (Ambroxol Hydrochloride EP Impurity E) Ambroxol EP Impurity E BroMhexine EP IMpurity B 50910-55-9 84477-98-7 C7H5Br2NO4 C7H5NOBr2 H2NC6H2Br2CHO Organic Building Blocks Carbonyl Compounds C7 Aldehydes Building Blocks Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals Aromatics Intermediates & Fine Chemicals