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5-Amino-2-bromobenzoic acid

CAS No.
2840-02-0
Chemical Name:
5-Amino-2-bromobenzoic acid
Synonyms
5-AMINO-2-BROMOBENZOIC;4-Bromo-3-carboxyaniline;2-Bromo-5-aminobenzoic acid;5-Amino-2-bromobenzoic acid;Benzoic acid, 5-amino-2-bromo-;5-Amino-2-bromobenzoic acid 94%;5-AMINO-2-BROMOBENZOIC ACID USP/EP/BP
CBNumber:
CB0707330
Molecular Formula:
C7H6BrNO2
Molecular Weight:
216.03
MDL Number:
MFCD07368968
MOL File:
2840-02-0.mol
MSDS File:
SDS
Last updated:2026-09-12 18:48:28

5-Amino-2-bromobenzoic acid Properties

Melting point 171-179 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Brown
Water Solubility Slightly soluble in water.
Major Application peptide synthesis
InChI InChI=1S/C7H6BrNO2/c8-6-2-1-4(9)3-5(6)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey FEXDUVBQBNYSQV-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC(N)=CC=C1Br
CAS DataBase Reference 2840-02-0(CAS DataBase Reference)
UNSPSC Code 12352106
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Danger
Hazard statements  H301-H315-H319-H335
Precautionary statements  P301+P310+P330-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36/37
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
Hazard Note  Harmful
HazardClass  6.1
HS Code  2922498590
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Limited Quantities 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
2 0

5-Amino-2-bromobenzoic acid price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 668036 5-Amino-2-bromobenzoic acid 94% 2840-02-0 5g $84.3 2023-06-20 Buy
Sigma-Aldrich 668036 5-Amino-2-bromobenzoic acid 94% 2840-02-0 25g $359 2023-06-20 Buy
TRC TRC-A602490-5G 5-Amino-2-bromobenzoic Acid 2840-02-0 5g $65 2026-06-03 Buy
TRC TRC-A602490-10G 5-Amino-2-bromobenzoic Acid 2840-02-0 10g $103 2026-06-03 Buy
Biosynth FA70334 5-Amino-2-bromobenzoic acid 2840-02-0 0.1kg $150 2026-06-04 Buy
Product number Packaging Price Buy
668036 5g $84.3 Buy
668036 25g $359 Buy
TRC-A602490-5G 5g $65 Buy
TRC-A602490-10G 10g $103 Buy
FA70334 0.1kg $150 Buy

5-Amino-2-bromobenzoic acid Chemical Properties, Uses, Production

Chemical Properties

White crystalline solid

Uses

It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuffs and is also used in medicine.

Uses

5-Amino-2-bromobenzoic Acid can be used for FABP4 and FABP4 inhibitors to prevent or treat FABP 4/5 related diseases.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

3-Aminobenzoic acid

99-05-8

5-AMINO-2-BROMOBENZOIC ACID

2840-02-0

General procedure for the synthesis of 5-amino-2-bromobenzoic acid from 3-aminobenzoic acid: 3-aminobenzoic acid (3.00 g, 21.9 mmol) was dissolved in N,N-dimethylformamide (18.0 mL) and cooled to below 5 °C. In another vessel, a solution was prepared by mixing N,N-dimethylformamide (9.00 mL) with N-bromosuccinimide (4.09 g, 23.0 mmol). This solution was slowly added to the cooled 3-aminobenzoic acid solution, keeping the reaction temperature at 5 °C or lower. The reaction mixture was stirred at 5 °C for 1 h. After the reaction mixture was stirred for 1 h, water (60.0 mL) was added and the stirring was continued for 12 h at 5 °C. Upon completion of the reaction, the solid product was collected by filtration, and the filtrate was washed with water (5.00 mL) and dried to give 5-amino-2-bromobenzoic acid (3.68 g, 78% yield). The structure of the product was confirmed by 1H-NMR (400 MHz, DMSO-D6): δ 5.49 (s, 2H), 6.59 (dd, J = 8.5,2.9Hz, 1H), 6.93 (d, J = 2.9Hz, 1H), 7.25 (d, J = 8.5Hz, 1H), 13.04 (s, 1H).

Purification Methods

Crystallise the acid from H2O or *C6H6 (m 128o). The acetyl derivative crystallises from H2O (as monohydrate) or absolute EtOH with m 196-197o (anhydrous). [Koopal Rec Trav Chim, Pays Bas 34 148 1915, Bamberger Chem Ber 57 2090 1924, Beilstein 14 H 413, 14 II 245.]

References

[1] Patent: US2013/310576, 2013, A1. Location in patent: Paragraph 0151

5-Amino-2-bromobenzoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 173)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58

View Latest Price from 5-Amino-2-bromobenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-AMINO-2-BROMOBENZOIC ACID pictures 2025-06-27 5-AMINO-2-BROMOBENZOIC ACID
2840-02-0
1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
5-AMINO-2-BROMOBENZOIC ACID pictures 2025-06-20 5-AMINO-2-BROMOBENZOIC ACID
2840-02-0
$7.00-30.00 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
5-AMINO-2-BROMOBENZOIC ACID pictures 2021-08-12 5-AMINO-2-BROMOBENZOIC ACID
2840-02-0
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

5-Amino-2-bromobenzoic acid Spectrum

4-Bromo-3-carboxyaniline 5-AMINO-2-BROMOBENZOIC 2-Bromo-5-aminobenzoic acid 5-Amino-2-bromobenzoic acid 94% Benzoic acid, 5-amino-2-bromo- 5-AMINO-2-BROMOBENZOIC ACID USP/EP/BP 5-Amino-2-bromobenzoic acid 2840-02-0 Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Phenylacetic acid Aromatic Amino AcidsCarbonyl Compounds C7 Carboxylic Acids Peptide Synthesis Unnatural Amino Acid Derivatives