2-Amino-5-bromobenzoic acid
- CAS No.
- 5794-88-7
- Chemical Name:
- 2-Amino-5-bromobenzoic acid
- Synonyms
- 5-BROMOANTHRANILIC ACID;2-Amino-5-bromobenzoic;5-BROMO-2-AMINOBENZOIC ACID;BUTTPARK 89\07-49;RARECHEM AL BO 1183;5-bromo-anthranilicaci;5-Bromoantharanilic Acid;2-amino-5-bromo-benzoicaci;Anthranilic acid, 5-bromo-;2-AMINO-5-BROMOBENZOIC ACID
- CBNumber:
- CB7154465
- Molecular Formula:
- C7H6BrNO2
- Molecular Weight:
- 216.03
- MDL Number:
- MFCD00007823
- MOL File:
- 5794-88-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 213-215 °C (lit.) |
|---|---|
| Boiling point | 265.51°C (rough estimate) |
| Density | 1.6841 (rough estimate) |
| refractive index | 1.6120 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in methanol and dimethyl sulfoxide. |
| form | Powder |
| pka | 4.55±0.10(Predicted) |
| color | Beige |
| Sensitive | Light Sensitive |
| Merck | 14,1405 |
| BRN | 639028 |
| Major Application | peptide synthesis |
| InChI | InChI=1S/C7H6BrNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11) |
| InChIKey | CUKXRHLWPSBCTI-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(Br)=CC=C1N |
| CAS DataBase Reference | 5794-88-7(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | Q30190723F |
| NIST Chemistry Reference | 2-Amino-5-bromobenzoic acid(5794-88-7) |
| UNSPSC Code | 12352106 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37 | |||||||||
| Safety Statements | 26-38-36/37 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | CB2557670 | |||||||||
| Hazard Note | Harmful | |||||||||
| PackingGroup | 6.1/PG 3 | |||||||||
| HS Code | 29224999 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
2-Amino-5-bromobenzoic acid price More Price(84)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 260118 | 2-Amino-5-bromobenzoic acid 97% | 5794-88-7 | 5g | $64.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 260118 | 2-Amino-5-bromobenzoic acid 97% | 5794-88-7 | 25g | $65.8 | 2026-04-30 | Buy |
| TCI Chemical | A1254 | 5-Bromoanthranilic Acid >98.0%(HPLC)(T) | 5794-88-7 | 5g | $23 | 2026-04-30 | Buy |
| TCI Chemical | A1254 | 5-Bromoanthranilic Acid >98.0%(HPLC)(T) | 5794-88-7 | 25g | $57 | 2026-04-30 | Buy |
| Usbiological | 229810 | 2-Amino-5-bromobenzoic acid 98+% ≥98% | 25g | $163 | 2026-06-03 | Buy |
2-Amino-5-bromobenzoic acid Chemical Properties,Uses,Production
Synthesis
A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid at 15 °С and the mixture was stirred for 1 h at the same temperature. The product was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids containing mixture (0.5 g) was added to 10 mL of boiling water followed by the addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum. The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate. IR (suspension in nujol, cm−1 ): 3497, 3383, 1675, 1616, 1587, 1548, 1423, 1377, 1316, 1292, 1239, 1160, 1127, 812, 748, 691.
Chemical Properties
slight yellow to white powder
Physical properties
2-Amino-5-bromobenzoic acid has 17 atoms, meaning 45 vibrational modes in three main parts: Carboxyl group, amine group, and benzene. The molecule's most mechanically active parts are the carboxyl and amine groups. They exhibit rocking, swinging, and every kind of mechanical motion beside H immigrations between each other. For this reason, the molecule is not a simple carboxylic acid nor a primary amine[1].
Uses
2-Amino-5-bromobenzoic acid is a brominated derivative of Antharilinic Acid (A679222). 2-Amino-5-bromobenzoic acid displays plant growth-regulator activity. 2-Amino-5-bromobenzoic acid is used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors.
Uses
It is used in the preparation of hepatitis C virus NS5b RNA polymerase inhibitors. Also used in the determination of cobalt, copper, nickel, and zinc.
Preparation
2-Amino-5-bromobenzoic acid is synthesized from o-aminobenzoic acid by bromination.
Synthesis of 2-amino-5-bromobenzoic acid (4c, CAS: 5794-88-7) and 2-amino3,5-dibromobenzoic acid (4d, CAS: 609-85-8): A solution of bromine (7.2 g, 2 mL, 40 mmol) in 47 mL glacial acetic acid was added dropwise to sodium 2-aminobenzoate (6.4 g, 40 mmol) in 32 mL of glacial acetic acid at 15 °С and the mixture was stirred for 1 h at the same temperature. The product was filtered off, washed with benzene and dried in the dark. The bromobenzoic acids containing mixture (0.5 g) was added to 10 mL of boiling water followed by the addition of 1.3 mL of concentrated hydrochloric acid and hot filtration under vacuum. The insoluble material contained 2-amino-3,5-dibromobenzoic acid, whereas 2- amino-5-bromobenzoic acid precipitated upon cooling of the filtrate.
2-Amino-5-bromobenzoic acid (4c) IR (suspension in nujol, cm1 ): 3497, 3383, 1675, 1616, 1587, 1548, 1423, 1377, 1316, 1292, 1239, 1160, 1127, 812, 748, 691.
reaction suitability
reaction type: solution phase peptide synthesis
References
[1] Kunduracioglu, Ahmet . "Tautomeric Forms of 2–Amino–5–Bromobenzoic Acid: A DFT Study for Structural and Molecular Orbital Analysis." (2021).
2-Amino-5-bromobenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Inner Mongolia Yida Chemical Technology Co., Ltd. | 18967392038 | 67247734@qq.com | China | 75 | 58 |
| Dalian lichuang Chemical Co., Ltd | 0411-0411-00000000 13644282108 | 3500508746@qq.com | China | 2942 | 55 |
| Jinan Junhe Pharmaceutical Co., Ltd | 13475558980 13475558980 | 644535754@qq.com | China | 345 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Liaoning Tianhua Chemical Co., Ltd. | 0418-6530555 2855550 | China | 338 | 69 | |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
View Lastest Price from 2-Amino-5-bromobenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-02 | 2-Amino-5-bromobenzoic acid
5794-88-7
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2026-05-18 | 5-Bromoanthranilic acid
5794-88-7
|
1kg | 98% | Hefei Lbao Physical & Chemical Science Co.,Ltd | |||
 |
2025-05-23 | 2-Amino-5-bromobenzoic acid
5794-88-7
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-
- 2-Amino-5-bromobenzoic acid
5794-88-7
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 5-Bromoanthranilic acid
5794-88-7
- $0.00
- 98%
- Hefei Lbao Physical & Chemical Science Co.,Ltd
-
- 2-Amino-5-bromobenzoic acid
5794-88-7
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
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