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2-(3-Bromopropoxy)tetrahydro-2H-pyran

2-(3-Bromopropoxy)tetrahydro-2H-pyran structure

CAS No.: 33821-94-2

Chemical Name:: 2-(3-Bromopropoxy)tetrahydro-2H-pyran

Synonyms: AURORA KA-6729;2-(3-Bomopropoxy)oxane;2-(3-broMopropoxy)oxane;2-(3-Bromopropoxy)Tetrahydro-2;2-(3-bromopropoxy)tetrahydropyran;3-broMopropyltetrahydropyranylether;2-(Bromopropoxy)tetrahydro-2H-pyran;3-Bromo-O-tetrahydropyranyl-propanol;2-(3-BROMOPROPOXY)TETRAHYDRO-2H-PYRAN;2-(3-bromopropoxy)tetrahydro-1H-pyran

CBNumber:: CB0779744

Molecular Formula:: C8H15BrO2

Molecular Weight:: 223.11

MDL Number:: MFCD00058593

MOL File:: 33821-94-2.mol

MSDS File:: SDS

Last updated:2026-05-27 22:51:45

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2-(3-Bromopropoxy)tetrahydro-2H-pyran Properties

Boiling point	64.5 °C/0.8 mmHg (lit.)
Density	1.317 g/mL at 25 °C (lit.)
refractive index	n20/D 1.478(lit.)
Flash point	222 °F
storage temp.	-20°C
form	liquid
Appearance	Colorless to light yellow Liquid
BRN	106236
InChI	InChI=1S/C8H15BrO2/c9-5-3-7-11-8-4-1-2-6-10-8/h8H,1-7H2
InChIKey	HJNHUFQGDJLQRS-UHFFFAOYSA-N
SMILES	C1(OCCCBr)OCCCC1
CAS DataBase Reference	33821-94-2(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H332-H335
Precautionary statements	P261-P280-P305+P351+P338
PPE	Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Hazard Codes	Xi
Safety Statements	23-24/25
WGK Germany	3
F	8-10
Hazard Note	Irritant
HS Code	29329900
Storage Class	10 - Combustible liquids

2-(3-Bromopropoxy)tetrahydro-2H-pyran price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	415979	2-(3-Bromopropoxy)tetrahydro-2H-pyran 98%	33821-94-2	5g	$209	2026-04-30	Buy
TCI Chemical	B3187	2-(3-Bromopropoxy)tetrahydro-2H-pyran (stabilized with K2CO3) min. 95.0 %	33821-94-2	1G	$70	2026-04-30	Buy
TCI Chemical	B3187	2-(3-Bromopropoxy)tetrahydro-2H-pyran (stabilized with K2CO3) min. 95.0 %	33821-94-2	5G	$210	2026-04-30	Buy
Apolloscientific	OR24692	2-(3-Bromopropoxy)tetrahydro-2H-pyran ≥95%	33821-94-2	250mg	$21	2026-06-04	Buy
Synthonix	B47142	2-(3-Bromopropoxy)tetrahydro-2H-pyran 95%	33821-94-2	1g	$23	2026-05-06	Buy

Product number	Packaging	Price	Buy
415979	5g	$209	Buy
B3187	1G	$70	Buy
B3187	5G	$210	Buy
OR24692	250mg	$21	Buy
B47142	1g	$23	Buy

2-(3-Bromopropoxy)tetrahydro-2H-pyran Chemical Properties, Uses, Production

Chemical Properties

Clear colorless to yellow liquid

Uses

2-(3-Bromopropoxy)tetrahydro-2H-pyran may be used in organic synthesis studies.

General Description

The latent alcohol functionality of this bifunctional building block can be generated using aqueous acid.

Synthesis

110-87-2

627-18-9

33821-94-2

GENERAL STEPS: The synthesis of the compound was reported in the literature (Pinchuk, A.N. et al. J. Med. Chem. 2006, 49, 2155-2165). A solution of 3-bromo-1-propanol (6.95 g, 50 mmol, 1 eq.) in DCM (25 mL) was added to a 125 mL round-bottomed flask, and 3,4-dihydro-2H-pyran (5.93 mL, 65 mmol, 1.3 eq.) was added slowly with stirring. The reaction mixture was stirred at room temperature overnight and the progress of the reaction was monitored by TLC (Spreader: 20% EtOAc in hexane solution, Color Developer: KMnO4) to confirm complete consumption of 3-bromo-1-propanol. After completion of the reaction, the solvent was evaporated under reduced pressure, and the resulting crude product was purified by rapid column chromatography on silica gel (silica gel dosage: 20 g, column diameter: 1.5 cm, eluent: 10% EtOAc/hexane, 100 mL) to afford 2-(3-bromopropoxy)tetrahydro-2H-pyran as a colorless, transparent oil in 86.4% yield (9.637 g). The product was detected by TLC (20% EtOAc in hexane solution) with Rf = 0.85. The NMR data were as follows: 1H NMR (400 MHz, CDCl3) δ: 4.59 (t, 1H, J = 3.52 Hz, H-7), 3.90-3.81 (m, 2H, H-6), 3.55-3.47 (m, 4H, H-4 + H-5), 2.16-2.08 (m, 2H, H-3), 1.90-1.64 (m, 2H, H-2), 1.57-1.50 (m, 4H, H-1); 13C NMR (100 MHz, CDCl3) δ: 98.90 (C-7), 64.88 (C-6), 62.26 (C-5), 32.90 (C-3), 30.59 (d, 2J-3) 30.59 (d, 2J = 6.04 Hz, C-4), 25.41 (C-2), 19.48 (C-1).

References

[1] Synthetic Communications, 2007, vol. 37, # 12, p. 2031 - 2037
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 7, p. 2155 - 2165
[3] Organic Letters, 2014, vol. 16, # 11, p. 2818 - 2821
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 51, p. 15497 - 15500
[5] Angew. Chem., 2015, vol. 127, # 51, p. 15717 - 15720

2-(3-Bromopropoxy)tetrahydro-2H-pyran Preparation Products And Raw materials

Raw materials

3,4-Dihydro-2H-pyran 3-Bromo-1-propanol

Preparation Products

Benzeneacetonitrile, 3,4-dichloro-α-[3-[(tetrahydro-2H-pyran-2-yl)oxy]propyl]-

2-(3-Bromopropoxy)tetrahydro-2H-pyran Suppliers

Global Suppliers ( 174)

Supplier	Tel	Email	Country	ProdList	Advantage
ShldaTech. Co., Ltd.	18014808303	3674571109@qq.com	China	33	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Jia Xing Isenchem Co.,Ltd	0573-85285100 18627885956	isenchem@163.com	China	9389	66
Accela ChemBio Co.,Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	10972	64
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16306	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42917	64
Chengdu Ai Keda Chemical Technology Co., Ltd.	4008-755-333 18080918076	800078821@qq.com	China	9706	55
Shanghai Youd Chemical Technology Co., Ltd.	021-37910092 15821801668	cong44@126.com	China	286	58

Supplier	Advantage
ShldaTech. Co., Ltd.	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
Energy Chemical	61
Jia Xing Isenchem Co.,Ltd	66
Accela ChemBio Co.,Ltd.	64
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai Hanhong Scientific Co.,Ltd.	64
Chengdu Ai Keda Chemical Technology Co., Ltd.	55
Shanghai Youd Chemical Technology Co., Ltd.	58

View Latest Price from 2-(3-Bromopropoxy)tetrahydro-2H-pyran manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	2-(3-Bromopropoxy)tetrahydro-2H-pyran 33821-94-2	$1.10	1g	99.00%	100 Tons Min	Dideu Industries Group Limited
2021-08-12	2-(3-Bromopropoxy)tetrahydro-2H-pyran 33821-94-2	$10.00-15.00	1KG	99%+ HPLC		Zhuozhou Wenxi import and Export Co., Ltd
2019-07-10	2-(3-Bromopropoxy)tetrahydro-2H-pyran 33821-94-2	$1.00	1KG	99%	1ton	Career Henan Chemical Co

2-(3-Bromopropoxy)tetrahydro-2H-pyran
33821-94-2
$1.10
99.00%
Dideu Industries Group Limited

2-(3-Bromopropoxy)tetrahydro-2H-pyran
33821-94-2
$10.00-15.00
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

2-(3-Bromopropoxy)tetrahydro-2H-pyran
33821-94-2
$1.00
99%
Career Henan Chemical Co

2-(3-Bromopropoxy)tetrahydro-2H-pyran Spectrum

2-(3-Bromopropoxy)tetrahydro-2H-pyran(33821-94-2)¹HNMR 2-(3-Bromopropoxy)tetrahydro-2H-pyran(33821-94-2)FT-IR 2-(3-Bromopropoxy)tetrahydro-2H-pyran(33821-94-2)IR

33821-94-2 (2-(3-Bromopropoxy)tetrahydro-2H-pyran) Related Search:

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2-(3-Bromopropoxy)tetrahydro-2H-pyran,98%,stabilized with potassium carbonate 2-(3-Bromopropoxy)tetrahydro-2H-pyran,1-Bromo-3-(tetrahydropyranyloxy)propane 2-(3-Bromopropoxy)tetrahydro-2H-pyran, stabilized with potassium carbonate, 98% 3-Bromo-O-tetrahydropyranyl-propanol 2-(3-broMopropoxy)oxane 3-broMopropyltetrahydropyranylether 2-(3-Bromopropoxy)oxane, 1-Bromo-3-[(tetrahydro-2H-pyran-2-yl)oxy]propane 2-(3-BROMOPROPOXY)TETRAHYDRO-2H-PYRAN 1-BROMO-3-(TETRAHYDROPYRANYLOXY)PROPANE AURORA KA-6729 2-(3-Bomopropoxy)oxane 2-(3-Bromopropoxy)Tetrahydro-2 3-Bromo-O-tetrahydropyranyl-propanol, 95 % 2-(3-bromopropoxy)tetrahydropyran 2H-Pyran, 2-(3-bromopropoxy)tetrahydro- 2-(3-bromopropoxy)tetrahydro-1H-pyran 2-(3-Bromopropoxy)tetrahydro-2H-pyran ISO 9001：2015 REACH 2-(3-Bromopropoxy)tetrahydro-2H-pyran 2-(Bromopropoxy)tetrahydro-2H-pyran 3-bromopropyl tetrahydro-2H-pyran-2-yl ether BROMOPROPOXYTETRAHYDROPYRAN H232()---- 2-(3-Bromopropoxy)tetrahydro-2H-pyran , 2-(3-Bromopropoxy)tetrahydro-2H-pyran 33821-94-2 Halogenated Heterocycles Heterocyclic Building Blocks Pyrans HALOGEN Building Blocks Pyrans, Piperidines & Piperazines Pyrans, Piperidines &Piperazines