6-NITRO-5-METHYL (1H)INDAZOLE
- CAS No.
- 72521-00-7
- Chemical Name:
- 6-NITRO-5-METHYL (1H)INDAZOLE
- Synonyms
- 5-Methyl-6-nitroindazole;5-methyl-6-nitro-1H-indazole;6-NITRO-5-METHYL (1H)INDAZOLE;1H-Indazole, 5-methyl-6-nitro-
- CBNumber:
- CB0789747
- Molecular Formula:
- C8H7N3O2
- Molecular Weight:
- 177.16
- MDL Number:
- MFCD09026996
- MOL File:
- 72521-00-7.mol
- MSDS File:
- SDS
| Boiling point | 379.7±22.0 °C(Predicted) |
|---|---|
| Density | 1.437 |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 11.30±0.40(Predicted) |
| Appearance | Light yellow to yellow Solid |
| InChI | InChI=1S/C8H7N3O2/c1-5-2-6-4-9-10-7(6)3-8(5)11(12)13/h2-4H,1H3,(H,9,10) |
| InChIKey | AZWAXIMNWVYSMP-UHFFFAOYSA-N |
| SMILES | N1C2=C(C=C(C)C([N+]([O-])=O)=C2)C=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
6-NITRO-5-METHYL (1H)INDAZOLE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M339443 | 5-Methyl-6-nitro-1H-indazole | 72521-00-7 | 10mg | $45 | 2021-12-16 | Buy |
| Apolloscientific | OR948085 | 5-Methyl-6-nitro-1H-indazole 95% | 72521-00-7 | 1g | $115 | 2021-12-16 | Buy |
| AK Scientific | Y9920 | 5-Methyl-6-nitro-1H-indazole | 72521-00-7 | 10g | $197 | 2021-12-16 | Buy |
| Apolloscientific | OR948085 | 5-Methyl-6-nitro-1H-indazole 95% | 72521-00-7 | 5g | $240 | 2021-12-16 | Buy |
| Apolloscientific | OR948085 | 5-Methyl-6-nitro-1H-indazole 95% | 72521-00-7 | 10g | $385 | 2021-12-16 | Buy |
6-NITRO-5-METHYL (1H)INDAZOLE Chemical Properties,Uses,Production
Synthesis
2124-47-2
72521-00-7
The general procedure for the synthesis of 5-methyl-6-nitroindazole from 2,4-dimethyl-5-nitroaniline is as follows: 1. 2,4-dimethyl-5-nitroaniline (1.662 g, 10.00 mmol) was dissolved in glacial acetic acid (100 ml) and the mixture was cooled to 0°C. 2. Sodium nitrite solution (1 equiv, 690 mg dissolved in 2 ml of water) was slowly added while keeping the reaction temperature below 25 °C. 3. Stirring of the reaction mixture was continued for 3 hours, followed by filtration. 4. The filtrate was allowed to stand at room temperature for 3 days and then concentrated under reduced pressure. 5. The concentrated residue was diluted with water and the resulting mixture was vigorously stirred. 6. The solid product was collected by filtration, washed thoroughly with cold water and dried. 7. 7. Finally, the product was purified by fast chromatography (dichloromethane/methanol with an eluent ratio of 99:1) to give 1.030 g (58.1% yield) of 5-methyl-6-nitro-1H-indazole in solid form.
References
[1] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 3, p. 403 - 427
[2] Patent: US2010/160373, 2010, A1. Location in patent: Page/Page column 28-29
[3] Patent: US2011/71143, 2011, A1. Location in patent: Page/Page column 37
[4] Journal of Medicinal Chemistry, 2015, vol. 58, # 21, p. 8413 - 8426
[5] Patent: WO2007/95124, 2007, A2. Location in patent: Page/Page column 89-90
6-NITRO-5-METHYL (1H)INDAZOLE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29800 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| KARMEL TECHNOLOGY (HK) CO.,LIMITED | +8618795957998 | karmelhk@126.com | CHINA | 2886 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5661 | 58 |
View Lastest Price from 6-NITRO-5-METHYL (1H)INDAZOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-13 | 6-NITRO-5-METHYL (1H)INDAZOLE
72521-00-7
|
US $1.00 / KG | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 6-NITRO-5-METHYL (1H)INDAZOLE
72521-00-7
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
