1-PYRIDIN-4-YLPIPERIDIN-4-ONE
- CAS No.
- 126832-81-3
- Chemical Name:
- 1-PYRIDIN-4-YLPIPERIDIN-4-ONE
- Synonyms
- 1-pyridin-4-yl-4-piperidinone;1-PYRIDIN-4-YLPIPERIDIN-4-ONE;1-(4-Pyridinyl)-4-piperidinone;4-Piperidinone, 1-(4-pyridinyl)-;2,3,5,6-TETRAHYDRO-[1,4']BIPYRIDINYL-4-ONE
- CBNumber:
- CB0795898
- Molecular Formula:
- C10H12N2O
- Molecular Weight:
- 176.22
- MDL Number:
- MFCD09030756
- MOL File:
- 126832-81-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Pyridin-4-ylpiperidin-4-one 97% | OR907054 | 100mg | $36 |
| 1-Pyridin-4-ylpiperidin-4-one 97% | OR907054 | 250mg | $43 |
| 1-Pyridin-4-ylpiperidin-4-one 97% | OR907054 | 1g | $69 |
| 1-Pyridin-4-ylpiperidin-4-one 97% | OR907054 | 5g | $240 |
| 1-Pyridin-4-ylpiperidin-4-one 97% | AS34012 | 1g | $105 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| HS Code | 2933399990 |
1-PYRIDIN-4-YLPIPERIDIN-4-ONE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR907054 | 1-Pyridin-4-ylpiperidin-4-one 97% | 126832-81-3 | 100mg | $36 | 2026-06-04 | Buy |
| Apolloscientific | OR907054 | 1-Pyridin-4-ylpiperidin-4-one 97% | 126832-81-3 | 250mg | $43 | 2026-06-04 | Buy |
| Apolloscientific | OR907054 | 1-Pyridin-4-ylpiperidin-4-one 97% | 126832-81-3 | 1g | $69 | 2026-06-04 | Buy |
| Apolloscientific | OR907054 | 1-Pyridin-4-ylpiperidin-4-one 97% | 126832-81-3 | 5g | $240 | 2026-06-04 | Buy |
| Activate Scientific | AS34012 | 1-Pyridin-4-ylpiperidin-4-one 97% | 126832-81-3 | 1g | $105 | 2026-06-04 | Buy |
1-PYRIDIN-4-YLPIPERIDIN-4-ONE Chemical Properties,Uses,Production
Synthesis
![8-(pyridin-4-yl)-1,4-dioxa-8-azaspiro[4.5]decane](/CAS/20180703/GIF/166954-75-2.gif)
166954-75-2
126832-81-3
The general procedure for the synthesis of 1-(4-pyridyl)-piperidin-4-one from the compound (CAS:166954-75-2) was as follows: 79.7 g of the aforementioned ketone was dissolved in 2 L of tetrahydrofuran, followed by the addition of 1000 mL of 6 N hydrochloric acid solution. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the solvent was removed by evaporation and concentration, and the pH was adjusted to alkaline with semi-concentrated ammonia. Extraction was carried out using dichloromethane and the combined organic phases were concentrated by evaporation to give 64.2 g (quantitative yield) of 2,3,5,6-tetrahydro-[1,4']bipyridin-4-one, which has a melting point of 102 °C.
References
[1] Patent: US2003/236266, 2003, A1. Location in patent: Page 7
[2] European Journal of Medicinal Chemistry, 2017, vol. 139, p. 128 - 152
[3] Patent: WO2010/81851, 2010, A1. Location in patent: Page/Page column 17
[4] Patent: US2012/71461, 2012, A1. Location in patent: Page/Page column 147
[5] Tetrahedron Letters, 2007, vol. 48, # 14, p. 2519 - 2525
1-PYRIDIN-4-YLPIPERIDIN-4-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32998 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; +86-85511178 | peter68@ptchemgroup.com | China | 35405 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49860 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57473 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai GaoDao Pharmaceutical Co., Ltd. | 021-15001867143 15001867143 | 1095570358@qq.com | China | 912 | 55 |
