ChemicalBook >> CAS DataBase List >>Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI)

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI)

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) structure

CAS No.: 330638-43-2

Chemical Name:: Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI)

Synonyms: SHMT-IN-3;SHMT inhibitor Hit 1;Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI);4,4'-((Pyrimidine-2,4-diylbis(4,1-phenylene))bis(azanediyl))bis(4-oxobutanoic acid)

CBNumber:: CB08249351

Molecular Formula:: C24H22N4O6

Molecular Weight:: 462.45

MDL Number:

MOL File:: 330638-43-2.mol

MSDS File:: SDS

Last updated:2025-04-18 09:51:35

Request For Quotation

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) Properties

Boiling point	787.0±60.0 °C(Predicted)
Density	1.410±0.06 g/cm3(Predicted)
pka	4.50±0.10(Predicted)

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	FNA63843	4,4'-((Pyrimidine-2,4-diylbis(4,1-phenylene))bis(azanediyl))bis(4-oxobutanoic acid)	330638-43-2	50mg	$910.5	2026-06-04	Buy
Biosynth	FNA63843	4,4'-((Pyrimidine-2,4-diylbis(4,1-phenylene))bis(azanediyl))bis(4-oxobutanoic acid)	330638-43-2	100mg	$1458	2026-06-04	Buy
ChemScene	CS-0635887	SHMT-IN-3	330638-43-2	5mg	$271	2026-06-04	Buy
aablocks	AA01PQJX	Butanoic acid, 4,4′-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- 90%	330638-43-2	1mg	$88	2026-05-31	Buy

Product number	Packaging	Price	Buy
FNA63843	50mg	$910.5	Buy
FNA63843	100mg	$1458	Buy
CS-0635887	5mg	$271	Buy
AA01PQJX	1mg	$88	Buy

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) Chemical Properties, Uses, Production

Uses

SHMT-IN-3 (Hit 1) is a SHMT1 and SHMT2 inhibitor with an IC50 of 0.53μM for human SHMT1. SHMT-IN-3 exhibits noncompetitive inhibition against serine[1].

IC 50

Human SHMT1: 0.53 μM (IC₅₀)

References

[1] Hiroshi Nonaka, et al. Design strategy for serine hydroxymethyltransferase probes based on retro-aldol-type reaction. Nat Commun. 2019 Feb 20;10(1):876. DOI:10.1038/s41467-019-08833-7

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Shaoyuan Technology (Shanghai) Co., Ltd.	021-50795510 4000665055	marketing@accelachem.com	China	9721	58
TargetMol	400-821-0310 15002144251	xuexiang.shao@tsbiochem.com	China	29128	58

Supplier	Advantage
Shaoyuan Technology (Shanghai) Co., Ltd.	58
TargetMol	58

330638-43-2 (Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI)) Related Search:

L-Glutamic acid, N-[4-[4-(2-amino-3,4-dihydro-4-oxo-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-2-fluorobenzoyl]- SHMT-IN-2 SHMT-IN-1 SHMT-IN-4 Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-1,4-dihydro-4-[3-(hydroxymethyl)-5-(5-hydroxy-1-pentyn-1-yl)phenyl]-3-methyl-4-(1-methylethyl)-, (4R)-

Butanoic acid, 4,4'-[2,4-pyrimidinediylbis(4,1-phenyleneimino)]bis[4-oxo- (9CI) SHMT inhibitor Hit 1 4,4'-((Pyrimidine-2,4-diylbis(4,1-phenylene))bis(azanediyl))bis(4-oxobutanoic acid) SHMT-IN-3 330638-43-2