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Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]-

Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- Structure
Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- structure
CAS No.
169521-68-0
Chemical Name:
Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]-
Synonyms
Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]-
CBNumber:
CB08382823
Molecular Formula:
C33H50N4O8
Molecular Weight:
630.78
MDL Number:
MOL File:
169521-68-0.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:31
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Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- Properties

Boiling point 819.7±65.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
pka 8.57±0.70(Predicted)

Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- Chemical Properties, Uses, Production

Uses

17-DMAP-GA, a Geldanamycin (HY-15230) analogue, is an inhibitor of HSP90. 17-DMAP-GA causes cell cycle abnormalities[1][2].

References

[1] Jurczyszyn A, et al. Geldanamycin and Its Derivatives Inhibit the Growth of Myeloma Cells and Reduce the Expression of the MET Receptor. J Cancer. 2014;5(6):480-490. Published 2014 May 31. DOI:10.7150/jca.8731
[2] Tian ZQ, et al. Synthesis and biological activities of novel 17-aminogeldanamycin derivatives. Bioorg Med Chem. 2004;12(20):5317-5329. DOI:10.1016/j.bmc.2004.07.053

Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- Suppliers

Global Suppliers ( 3)
Supplier Tel Email Country ProdList Advantage
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
RD International Technology Co., Limited 58
TargetMol Chemicals Inc. 58

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Geldanamycin, 17-demethoxy-17-[[3-(dimethylamino)propyl]amino]- 169521-68-0 C33H50N4O8